FimH antagonists for the oral treatment of urinary tract infections: from design and synthesis to in vitro and in vivo evaluation T Klein, D Abgottspon, M Wittwer, S Rabbani, J Herold, X Jiang, S Kleeb, ... Journal of medicinal chemistry 53 (24), 8627-8641, 2010 | 262 | 2010 |
FimH antagonists: bioisosteres to improve the in vitro and in vivo PK/PD profile S Kleeb, L Pang, K Mayer, D Eris, A Sigl, RC Preston, P Zihlmann, ... American Chemical Society, 2015 | 104 | 2015 |
FimH Antagonists: Structure–Activity and Structure–Property Relationships for Biphenyl α‐D‐Mannopyranosides L Pang, S Kleeb, K Lemme, S Rabbani, M Scharenberg, A Zalewski, ... ChemMedChem 7 (8), 1404-1422, 2012 | 94 | 2012 |
Target‐directed Dynamic Combinatorial Chemistry: A Study on Potentials and Pitfalls as Exemplified on a Bacterial Target P Frei, L Pang, M Silbermann, D Eriº, T Mühlethaler, O Schwardt, B Ernst Chemistry–A European Journal 23 (48), 11570-11577, 2017 | 37 | 2017 |
Encapsulating An Immunosuppressant Enhances Tolerance Induction by Siglec Engaging Tolerogenic Liposomes L Pang, MS Macauley, BM Arlian, CM Nycholat, JC Paulson ChemBioChem 18 (13), 1226 – 1233, 2017 | 37 | 2017 |
Kinetic properties of carbohydrate–lectin interactions: FimH antagonists M Scharenberg, X Jiang, L Pang, G Navarra, S Rabbani, F Binder, ... ChemMedChem 9 (1), 78-83, 2014 | 37 | 2014 |
Synthesis of neamine-derived pseudodisaccharides by stereo-and regio-selective functional group transformations LJ Pang, D Wang, J Zhou, LH Zhang, XS Ye Organic & Biomolecular Chemistry 7 (20), 4252-4266, 2009 | 30 | 2009 |
KinITC—one method supports both thermodynamic and kinetic SARs as exemplified on FimH antagonists P Zihlmann, M Silbermann, T Sharpe, X Jiang, T Mühlethaler, RP Jakob, ... Chemistry–A European Journal 24 (49), 13049-13057, 2018 | 27 | 2018 |
The conformational variability of FimH: which conformation represents the therapeutic target? D Eris, RC Preston, M Scharenberg, F Hulliger, D Abgottspon, L Pang, ... ChemBioChem 17 (11), 1012-1020, 2016 | 23 | 2016 |
Tolerogenic nanoparticles impacting B and T lymphocyte responses delay autoimmune arthritis in K/BxN mice A Srivastava, BM Arlian, L Pang, TK Kishimoto, JC Paulson ACS chemical biology 16 (10), 1985-1993, 2021 | 19 | 2021 |
Poly‐l‐lysine Glycoconjugates Inhibit DC‐SIGN‐mediated Attachment of Pandemic Viruses J Cramer, B Aliu, X Jiang, T Sharpe, L Pang, A Hadorn, S Rabbani, ... ChemMedChem 16 (15), 2345-2353, 2021 | 18 | 2021 |
FimH antagonists–solubility vs. permeability L Pang, J Bezençon, S Kleeb, S Rabbani, A Sigl, M Smiesko, CP Sager, ... | 3 | 2016 |
High-Affinity Carbohydrate–Lectin Interactions: How Nature Makes it Possible P Zihlmann, X Jiang, CP Sager, B Fiege, RP Jakob, S Siegrist, A Zalewski, ... Kinetic and Thermodynamic Characterization of the Bacterial Lectin FimH, 193, 0 | 1 | |
Optimized synthesis, polymer conjugation, and proof‐of‐concept studies of the gd‐IgA1 epitope for antibody‐scavenging therapies in IgA nephropathy C Bechtler, O Barneoud‐Rousset, L Pang, K Martin, KF König, P Hänggi, ... Chemical Biology & Drug Design 102 (3), 580-586, 2023 | | 2023 |
Glycopolymer binds pathogenic IgM autoantibodies and pulls them into the mononuclear phagocyte system for degradation B Aliu, D Demeestere, L Pang, T Sharpe, W Heusermann, R Herrendorff, ... Development of therapeutic glycopolymers for the treatment of peripheral …, 2021 | | 2021 |
Development of an anti-GM1 antibody-specific therapy for the treatment of Guillain-Barré Syndrome and Multifocal Motor Neuropathy B Aliu, L Pang, H Bialic, R McGonigal, E Seydoux, D Demesteere, ... Development of therapeutic glycopolymers for the treatment of peripheral …, 2021 | | 2021 |
Development of an anti-GM1 antibody-specific therapy for Guillain-Barre syndrome and multifocal motor neuropathy B Aliu, L Pang, H Bialic, H Willison, J Boucraut, J Bos, L van der Pol, ... JOURNAL OF THE PERIPHERAL NERVOUS SYSTEM 25 (4), 445-445, 2020 | | 2020 |
How to remove disease-causing autoantibodies-precision treatment for anti-MAG neuropathy B Aliu, D Demesteere, L Pang, T Sharpe, W Heusermann, A Steck, ... EUROPEAN JOURNAL OF NEUROLOGY 26, 263-263, 2019 | | 2019 |
Exploiting siglecs to modulate immune responses J Paulson, B Arlian, S Duan, L Edgar, C Kikuchi, M Macauley, ... FEBS OPEN BIO 8, 46-46, 2018 | | 2018 |
Siglecs: Putting the brakes on the immune system J Paulson, B Arlian, S Duan, L Edgar, C Kikuchi, M Macauley, C Nycholat, ... ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 255, 2018 | | 2018 |