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Joanna Kowalska
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Phosphorothioate cap analogs stabilize mRNA and increase translational efficiency in mammalian cells
E Grudzien-Nogalska, J Jemielity, J Kowalska, E Darzynkiewicz, ...
Rna 13 (10), 1745-1755, 2007
2702007
Phosphorothioate cap analogs increase stability and translational efficiency of RNA vaccines in immature dendritic cells and induce superior immune responses in vivo
AN Kuhn, M Diken, S Kreiter, A Selmi, J Kowalska, J Jemielity, ...
Gene therapy 17 (8), 961-971, 2010
2502010
Synthesis and characterization of mRNA cap analogs containing phosphorothioate substitutions that bind tightly to eIF4E and are resistant to the decapping pyrophosphatase DcpS
J Kowalska, M Lewdorowicz, J Zuberek, E Grudzien-Nogalska, ...
Rna 14 (6), 1119-1131, 2008
1432008
Drosophila miR2 primarily targets the m7GpppN cap structure for translational repression
A Zdanowicz, R Thermann, J Kowalska, J Jemielity, K Duncan, T Preiss, ...
Molecular cell 35 (6), 881-888, 2009
1062009
Vaccine composition comprising 5′-cap modified RNA
U Sahin, A Kuhn, E Darzynkiewicz, J Jemielity, J Kowalska
US Patent 9,295,717, 2016
942016
Synthetic mRNA cap analogs with a modified triphosphate bridge–synthesis, applications and prospects
J Jemielity, J Kowalska, AM Rydzik, E Darzynkiewicz
New Journal of Chemistry 34 (5), 829-844, 2010
912010
The identity and methylation status of the first transcribed nucleotide in eukaryotic mRNA 5′ cap modulates protein expression in living cells
PJ Sikorski, M Warminski, D Kubacka, T Ratajczak, D Nowis, J Kowalska, ...
Nucleic Acids Research 48 (4), 1607-1626, 2020
882020
Potential therapeutic applications of RNA cap analogs
M Ziemniak, M Strenkowska, J Kowalska, J Jemielity
Future medicinal chemistry 5 (10), 1141-1172, 2013
752013
Cap analogs modified with 1, 2-dithiodiphosphate moiety protect mRNA from decapping and enhance its translational potential
M Strenkowska, R Grzela, M Majewski, K Wnek, J Kowalska, ...
Nucleic acids research 44 (20), 9578-9590, 2016
732016
5′-phosphorothiolate dinucleotide cap analogues: Reagents for messenger RNA modification and potent small-molecular inhibitors of decapping enzymes
BA Wojtczak, PJ Sikorski, K Fac-Dabrowska, A Nowicka, M Warminski, ...
Journal of the American Chemical Society 140 (18), 5987-5999, 2018
722018
Synthetic mRNAs with superior translation and stability properties
E Grudzien-Nogalska, J Kowalska, W Su, AN Kuhn, SV Slepenkov, ...
Synthetic Messenger RNA and Cell Metabolism Modulation: Methods and …, 2013
712013
Synthesis, properties, and biological activity of boranophosphate analogs of the mRNA cap: versatile tools for manipulation of therapeutically relevant cap-dependent processes
J Kowalska, A Wypijewska del Nogal, ZM Darzynkiewicz, J Buck, C Nicola, ...
Nucleic acids research 42 (16), 10245-10264, 2014
702014
Synthesis and use of anti-reverse phosphorothioate analogs of the messenger RNA cap
J Jemielity, EM Grudzien-Nogalska, J Kowalska, E Darzynkiewicz, ...
672008
Synthesis and properties of mRNA cap analogs containing imidodiphosphate moiety—fairly mimicking natural cap structure, yet resistant to enzymatic hydrolysis
AM Rydzik, M Kulis, M Lukaszewicz, J Kowalska, J Zuberek, ...
Bioorganic & medicinal chemistry 20 (5), 1699-1710, 2012
612012
Synthetic dinucleotide mRNA cap analogs with tetraphosphate 5′, 5′ bridge containing methylenebis (phosphonate) modification
AM Rydzik, M Lukaszewicz, J Zuberek, J Kowalska, ZM Darzynkiewicz, ...
Organic & Biomolecular Chemistry 7 (22), 4763-4776, 2009
612009
Biomolecular condensates amplify mRNA decapping by biasing enzyme conformation
RW Tibble, A Depaix, J Kowalska, J Jemielity, JD Gross
Nature chemical biology 17 (5), 615-623, 2021
552021
Preparation of synthetically challenging nucleotides using cyanoethyl P-imidazolides and microwaves
M Strenkowska, P Wanat, M Ziemniak, J Jemielity, J Kowalska
Organic letters 14 (18), 4782-4785, 2012
552012
Roquin targets mRNAs in a 3′-UTR-specific manner by different modes of regulation
K Essig, N Kronbeck, JC Guimaraes, C Lohs, A Schlundt, A Hoffmann, ...
Nature communications 9 (1), 3810, 2018
532018
Virus-like particle-mediated intracellular delivery of mRNA cap analog with in vivo activity against hepatocellular carcinoma
M Zochowska, AC Piguet, J Jemielity, J Kowalska, E Szolajska, JF Dufour, ...
Nanomedicine: Nanotechnology, Biology and Medicine 11 (1), 67-76, 2015
502015
A simple and rapid synthesis of nucleotide analogues containing a phosphorothioate moiety at the terminal position of the phosphate chain
J Kowalska, M Lewdorowicz, E Darzynkiewicz, J Jemielity
Tetrahedron letters 48 (31), 5475-5479, 2007
502007
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