| Phosphorothioate cap analogs stabilize mRNA and increase translational efficiency in mammalian cells E Grudzien-Nogalska, J Jemielity, J Kowalska, E Darzynkiewicz, ... Rna 13 (10), 1745-1755, 2007 | 221 | 2007 |
| Phosphorothioate cap analogs increase stability and translational efficiency of RNA vaccines in immature dendritic cells and induce superior immune responses in vivo AN Kuhn, M Diken, S Kreiter, A Selmi, J Kowalska, J Jemielity, ... Gene therapy 17 (8), 961-971, 2010 | 194 | 2010 |
| Synthesis and characterization of mRNA cap analogs containing phosphorothioate substitutions that bind tightly to eIF4E and are resistant to the decapping pyrophosphatase DcpS J Kowalska, M Lewdorowicz, J Zuberek, E Grudzien-Nogalska, ... Rna 14 (6), 1119-1131, 2008 | 113 | 2008 |
| Drosophila miR2 primarily targets the m7GpppN cap structure for translational repression A Zdanowicz, R Thermann, J Kowalska, J Jemielity, K Duncan, T Preiss, ... Molecular cell 35 (6), 881-888, 2009 | 95 | 2009 |
| Vaccine composition comprising 5′-cap modified RNA U Sahin, A Kuhn, E Darzynkiewicz, J Jemielity, J Kowalska US Patent 9,295,717, 2016 | 81 | 2016 |
| Synthetic mRNA cap analogs with a modified triphosphate bridge–synthesis, applications and prospects J Jemielity, J Kowalska, AM Rydzik, E Darzynkiewicz New Journal of Chemistry 34 (5), 829-844, 2010 | 75 | 2010 |
| Potential therapeutic applications of RNA cap analogs M Ziemniak, M Strenkowska, J Kowalska, J Jemielity Future medicinal chemistry 5 (10), 1141-1172, 2013 | 60 | 2013 |
| Synthesis, properties, and biological activity of boranophosphate analogs of the mRNA cap: versatile tools for manipulation of therapeutically relevant cap-dependent processes J Kowalska, A Wypijewska del Nogal, ZM Darzynkiewicz, J Buck, C Nicola, ... Nucleic acids research 42 (16), 10245-10264, 2014 | 57 | 2014 |
| Synthetic dinucleotide mRNA cap analogs with tetraphosphate 5′, 5′ bridge containing methylenebis (phosphonate) modification AM Rydzik, M Lukaszewicz, J Zuberek, J Kowalska, ZM Darzynkiewicz, ... Organic & Biomolecular Chemistry 7 (22), 4763-4776, 2009 | 54 | 2009 |
| Cap analogs modified with 1, 2-dithiodiphosphate moiety protect mRNA from decapping and enhance its translational potential M Strenkowska, R Grzela, M Majewski, K Wnek, J Kowalska, ... Nucleic acids research 44 (20), 9578-9590, 2016 | 50 | 2016 |
| Synthetic mRNAs with superior translation and stability properties E Grudzien-Nogalska, J Kowalska, W Su, AN Kuhn, SV Slepenkov, ... Synthetic messenger RNA and cell metabolism modulation, 55-72, 2013 | 50 | 2013 |
| Synthesis and properties of mRNA cap analogs containing imidodiphosphate moiety—fairly mimicking natural cap structure, yet resistant to enzymatic hydrolysis AM Rydzik, M Kulis, M Lukaszewicz, J Kowalska, J Zuberek, ... Bioorganic & medicinal chemistry 20 (5), 1699-1710, 2012 | 50 | 2012 |
| Preparation of synthetically challenging nucleotides using cyanoethyl P-imidazolides and microwaves M Strenkowska, P Wanat, M Ziemniak, J Jemielity, J Kowalska Organic letters 14 (18), 4782-4785, 2012 | 48 | 2012 |
| A simple and rapid synthesis of nucleotide analogues containing a phosphorothioate moiety at the terminal position of the phosphate chain J Kowalska, M Lewdorowicz, E Darzynkiewicz, J Jemielity Tetrahedron letters 48 (31), 5475-5479, 2007 | 48 | 2007 |
| mRNAs containing the histone 3′ stem–loop are degraded primarily by decapping mediated by oligouridylation of the 3′ end W Su, SV Slepenkov, MK Slevin, SM Lyons, M Ziemniak, J Kowalska, ... Rna 19 (1), 1-16, 2013 | 47 | 2013 |
| 5′-phosphorothiolate dinucleotide cap analogues: Reagents for messenger RNA modification and potent small-molecular inhibitors of decapping enzymes BA Wojtczak, PJ Sikorski, K Fac-Dabrowska, A Nowicka, M Warminski, ... Journal of the American Chemical Society 140 (18), 5987-5999, 2018 | 44 | 2018 |
| Virus-like particle-mediated intracellular delivery of mRNA cap analog with in vivo activity against hepatocellular carcinoma M Zochowska, AC Piguet, J Jemielity, J Kowalska, E Szolajska, JF Dufour, ... Nanomedicine: Nanotechnology, Biology and Medicine 11 (1), 67-76, 2015 | 43 | 2015 |
| Synthesis and use of anti-reverse phosphorothioate analogs of the messenger RNA cap J Jemielity, EM Grudzien-Nogalska, J Kowalska, E Darzynkiewicz, ... | 41 | 2008 |
| The identity and methylation status of the first transcribed nucleotide in eukaryotic mRNA 5′ cap modulates protein expression in living cells PJ Sikorski, M Warminski, D Kubacka, T Ratajczak, D Nowis, J Kowalska, ... Nucleic acids research 48 (4), 1607-1626, 2020 | 37 | 2020 |
| Applications of phosphate modification and labeling to study (m) RNA caps M Warminski, PJ Sikorski, J Kowalska, J Jemielity Phosphate Labeling and Sensing in Chemical Biology, 211-239, 2017 | 37 | 2017 |
Jacek JemielityCentre of New Technologies, University of WarsawZweryfikowany adres z biogeo.uw.edu.pl
