Joanna Kowalska
Tytuł
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Phosphorothioate cap analogs stabilize mRNA and increase translational efficiency in mammalian cells
E Grudzien-Nogalska, J Jemielity, J Kowalska, E Darzynkiewicz, ...
RNA 13 (10), 1745-1755, 2007
1762007
Phosphorothioate cap analogs increase stability and translational efficiency of RNA vaccines in immature dendritic cells and induce superior immune responses in vivo
AN Kuhn, M Diken, S Kreiter, A Selmi, J Kowalska, J Jemielity, ...
Gene therapy 17 (8), 961-971, 2010
1502010
Synthesis and characterization of mRNA cap analogs containing phosphorothioate substitutions that bind tightly to eIF4E and are resistant to the decapping pyrophosphatase DcpS
J Kowalska, M Lewdorowicz, J Zuberek, E Grudzien-Nogalska, ...
Rna 14 (6), 1119-1131, 2008
892008
Drosophila miR2 primarily targets the m7GpppN cap structure for translational repression
A Zdanowicz, R Thermann, J Kowalska, J Jemielity, K Duncan, T Preiss, ...
Molecular cell 35 (6), 881-888, 2009
872009
Vaccine composition comprising 5′-cap modified RNA
U Sahin, A Kuhn, E Darzynkiewicz, J Jemielity, J Kowalska
US Patent 9,295,717, 2016
692016
Synthetic mRNA cap analogs with a modified triphosphate bridge–synthesis, applications and prospects
J Jemielity, J Kowalska, AM Rydzik, E Darzynkiewicz
New Journal of Chemistry 34 (5), 829-844, 2010
642010
Potential therapeutic applications of RNA cap analogs
M Ziemniak, M Strenkowska, J Kowalska, J Jemielity
Future medicinal chemistry 5 (10), 1141-1172, 2013
492013
mRNAs containing the histone 3′ stem–loop are degraded primarily by decapping mediated by oligouridylation of the 3′ end
W Su, SV Slepenkov, MK Slevin, SM Lyons, M Ziemniak, J Kowalska, ...
Rna 19 (1), 1-16, 2013
472013
Synthetic dinucleotide mRNA cap analogs with tetraphosphate 5′, 5′ bridge containing methylenebis (phosphonate) modification
AM Rydzik, M Lukaszewicz, J Zuberek, J Kowalska, ZM Darzynkiewicz, ...
Organic & biomolecular chemistry 7 (22), 4763-4776, 2009
462009
A simple and rapid synthesis of nucleotide analogues containing a phosphorothioate moiety at the terminal position of the phosphate chain
J Kowalska, M Lewdorowicz, E Darzynkiewicz, J Jemielity
Tetrahedron letters 48 (31), 5475-5479, 2007
452007
Preparation of synthetically challenging nucleotides using cyanoethyl P-imidazolides and microwaves
M Strenkowska, P Wanat, M Ziemniak, J Jemielity, J Kowalska
Organic letters 14 (18), 4782-4785, 2012
422012
Synthesis, properties, and biological activity of boranophosphate analogs of the mRNA cap: versatile tools for manipulation of therapeutically relevant cap-dependent processes
J Kowalska, A Wypijewska del Nogal, ZM Darzynkiewicz, J Buck, C Nicola, ...
Nucleic acids research 42 (16), 10245-10264, 2014
412014
Synthesis and properties of mRNA cap analogs containing imidodiphosphate moiety—fairly mimicking natural cap structure, yet resistant to enzymatic hydrolysis
AM Rydzik, M Kulis, M Lukaszewicz, J Kowalska, J Zuberek, ...
Bioorganic & medicinal chemistry 20 (5), 1699-1710, 2012
412012
Synthetic mRNAs with superior translation and stability properties
E Grudzien-Nogalska, J Kowalska, W Su, AN Kuhn, SV Slepenkov, ...
Synthetic messenger RNA and cell metabolism modulation, 55-72, 2013
322013
Translation, stability, and resistance to decapping of mRNAs containing caps substituted in the triphosphate chain with BH3, Se, and NH
W Su, S Slepenkov, E Grudzien-Nogalska, J Kowalska, M Kulis, ...
RNA 17 (5), 978-988, 2011
322011
Cap analogs modified with 1, 2-dithiodiphosphate moiety protect mRNA from decapping and enhance its translational potential
M Strenkowska, R Grzela, M Majewski, K Wnek, J Kowalska, ...
Nucleic acids research 44 (20), 9578-9590, 2016
312016
Virus-like particle-mediated intracellular delivery of mRNA cap analog with in vivo activity against hepatocellular carcinoma
M Zochowska, AC Piguet, J Jemielity, J Kowalska, E Szolajska, JF Dufour, ...
Nanomedicine: Nanotechnology, Biology and Medicine 11 (1), 67-76, 2015
302015
Recognition of different nucleotidyl-derivatives as substrates of reactions catalyzed by various HIT-proteins
A Guranowski, AM Wojdyła, J Zimny, A Wypijewska, J Kowalska, ...
New Journal of Chemistry 34 (5), 888-893, 2010
292010
Phosphorothioate analogs of m7GTP are enzymatically stable inhibitors of cap-dependent translation
J Kowalska, M Lukaszewicz, J Zuberek, M Ziemniak, E Darzynkiewicz, ...
Bioorganic & medicinal chemistry letters 19 (7), 1921-1925, 2009
292009
Synthesis and use of anti-reverse phosphorothioate analogs of the messenger RNA cap
J Jemielity, EM Grudzien-Nogalska, J Kowalska, E Darzynkiewicz, ...
US Patent 8,153,773, 2012
272012
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