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Joanna Kowalska
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Phosphorothioate cap analogs stabilize mRNA and increase translational efficiency in mammalian cells
E Grudzien-Nogalska, J Jemielity, J Kowalska, E Darzynkiewicz, ...
Rna 13 (10), 1745-1755, 2007
2212007
Phosphorothioate cap analogs increase stability and translational efficiency of RNA vaccines in immature dendritic cells and induce superior immune responses in vivo
AN Kuhn, M Diken, S Kreiter, A Selmi, J Kowalska, J Jemielity, ...
Gene therapy 17 (8), 961-971, 2010
1942010
Synthesis and characterization of mRNA cap analogs containing phosphorothioate substitutions that bind tightly to eIF4E and are resistant to the decapping pyrophosphatase DcpS
J Kowalska, M Lewdorowicz, J Zuberek, E Grudzien-Nogalska, ...
Rna 14 (6), 1119-1131, 2008
1132008
Drosophila miR2 primarily targets the m7GpppN cap structure for translational repression
A Zdanowicz, R Thermann, J Kowalska, J Jemielity, K Duncan, T Preiss, ...
Molecular cell 35 (6), 881-888, 2009
952009
Vaccine composition comprising 5′-cap modified RNA
U Sahin, A Kuhn, E Darzynkiewicz, J Jemielity, J Kowalska
US Patent 9,295,717, 2016
812016
Synthetic mRNA cap analogs with a modified triphosphate bridge–synthesis, applications and prospects
J Jemielity, J Kowalska, AM Rydzik, E Darzynkiewicz
New Journal of Chemistry 34 (5), 829-844, 2010
752010
Potential therapeutic applications of RNA cap analogs
M Ziemniak, M Strenkowska, J Kowalska, J Jemielity
Future medicinal chemistry 5 (10), 1141-1172, 2013
602013
Synthesis, properties, and biological activity of boranophosphate analogs of the mRNA cap: versatile tools for manipulation of therapeutically relevant cap-dependent processes
J Kowalska, A Wypijewska del Nogal, ZM Darzynkiewicz, J Buck, C Nicola, ...
Nucleic acids research 42 (16), 10245-10264, 2014
572014
Synthetic dinucleotide mRNA cap analogs with tetraphosphate 5′, 5′ bridge containing methylenebis (phosphonate) modification
AM Rydzik, M Lukaszewicz, J Zuberek, J Kowalska, ZM Darzynkiewicz, ...
Organic & Biomolecular Chemistry 7 (22), 4763-4776, 2009
542009
Cap analogs modified with 1, 2-dithiodiphosphate moiety protect mRNA from decapping and enhance its translational potential
M Strenkowska, R Grzela, M Majewski, K Wnek, J Kowalska, ...
Nucleic acids research 44 (20), 9578-9590, 2016
502016
Synthetic mRNAs with superior translation and stability properties
E Grudzien-Nogalska, J Kowalska, W Su, AN Kuhn, SV Slepenkov, ...
Synthetic messenger RNA and cell metabolism modulation, 55-72, 2013
502013
Synthesis and properties of mRNA cap analogs containing imidodiphosphate moiety—fairly mimicking natural cap structure, yet resistant to enzymatic hydrolysis
AM Rydzik, M Kulis, M Lukaszewicz, J Kowalska, J Zuberek, ...
Bioorganic & medicinal chemistry 20 (5), 1699-1710, 2012
502012
Preparation of synthetically challenging nucleotides using cyanoethyl P-imidazolides and microwaves
M Strenkowska, P Wanat, M Ziemniak, J Jemielity, J Kowalska
Organic letters 14 (18), 4782-4785, 2012
482012
A simple and rapid synthesis of nucleotide analogues containing a phosphorothioate moiety at the terminal position of the phosphate chain
J Kowalska, M Lewdorowicz, E Darzynkiewicz, J Jemielity
Tetrahedron letters 48 (31), 5475-5479, 2007
482007
mRNAs containing the histone 3′ stem–loop are degraded primarily by decapping mediated by oligouridylation of the 3′ end
W Su, SV Slepenkov, MK Slevin, SM Lyons, M Ziemniak, J Kowalska, ...
Rna 19 (1), 1-16, 2013
472013
5′-phosphorothiolate dinucleotide cap analogues: Reagents for messenger RNA modification and potent small-molecular inhibitors of decapping enzymes
BA Wojtczak, PJ Sikorski, K Fac-Dabrowska, A Nowicka, M Warminski, ...
Journal of the American Chemical Society 140 (18), 5987-5999, 2018
442018
Virus-like particle-mediated intracellular delivery of mRNA cap analog with in vivo activity against hepatocellular carcinoma
M Zochowska, AC Piguet, J Jemielity, J Kowalska, E Szolajska, JF Dufour, ...
Nanomedicine: Nanotechnology, Biology and Medicine 11 (1), 67-76, 2015
432015
Synthesis and use of anti-reverse phosphorothioate analogs of the messenger RNA cap
J Jemielity, EM Grudzien-Nogalska, J Kowalska, E Darzynkiewicz, ...
412008
The identity and methylation status of the first transcribed nucleotide in eukaryotic mRNA 5′ cap modulates protein expression in living cells
PJ Sikorski, M Warminski, D Kubacka, T Ratajczak, D Nowis, J Kowalska, ...
Nucleic acids research 48 (4), 1607-1626, 2020
372020
Applications of phosphate modification and labeling to study (m) RNA caps
M Warminski, PJ Sikorski, J Kowalska, J Jemielity
Phosphate Labeling and Sensing in Chemical Biology, 211-239, 2017
372017
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