David E. Gloriam
David E. Gloriam
Department of Drug Design and Pharmacology, University of Copenhagen
Verified email at - Homepage
Cited by
Cited by
Trends in GPCR drug discovery: new agents, targets and indications
AS Hauser, MM Attwood, M Rask-Andersen, HB Schiöth, DE Gloriam
Nature reviews Drug discovery 16 (12), 829-842, 2017
Pharmacogenomics of GPCR drug targets
AS Hauser, S Chavali, I Masuho, LJ Jahn, KA Martemyanov, DE Gloriam, ...
Cell 172 (1), 41-54. e19, 2018
Comprehensive repertoire and phylogenetic analysis of the G protein-coupled receptors in human and mouse
TK Bjarnadóttir, DE Gloriam, SH Hellstrand, H Kristiansson, R Fredriksson, ...
Genomics 88 (3), 263-273, 2006
GPCRdb in 2018: adding GPCR structure models and ligands
G Pándy-Szekeres, C Munk, TM Tsonkov, S Mordalski, K Harpsøe, ...
Nucleic acids research 46 (D1), D440-D446, 2018
Generic GPCR residue numbers–aligning topology maps while minding the gaps
V Isberg, C De Graaf, A Bortolato, V Cherezov, V Katritch, FH Marshall, ...
Trends in pharmacological sciences 36 (1), 22-31, 2015
GPCRdb: an information system for G protein-coupled receptors
V Isberg, S Mordalski, C Munk, K Rataj, K Harpsøe, AS Hauser, B Vroling, ...
Nucleic acids research 44 (D1), D356-D364, 2016
Selectivity determinants of GPCR–G-protein binding
T Flock, AS Hauser, N Lund, DE Gloriam, S Balaji, MM Babu
Nature 545 (7654), 317-322, 2017
Seven evolutionarily conserved human rhodopsin G protein‐coupled receptors lacking close relatives
R Fredriksson, PJ Höglund, DEI Gloriam, MC Lagerström, HB Schiöth
FEBS letters 554 (3), 381-388, 2003
GPCRdb in 2021: integrating GPCR sequence, structure and function
AJ Kooistra, S Mordalski, G Pándy-Szekeres, M Esguerra, A Mamyrbekov, ...
Nucleic Acids Research 49 (D1), D335-D343, 2021
SMARTCyp: a 2D method for prediction of cytochrome P450-mediated drug metabolism
P Rydberg, DE Gloriam, J Zaretzki, C Breneman, L Olsen
ACS medicinal chemistry letters 1 (3), 96-100, 2010
The human and mouse repertoire of the adhesion family of G-protein-coupled receptors
TK Bjarnadóttir, R Fredriksson, PJ Höglund, DE Gloriam, MC Lagerström, ...
Genomics 84 (1), 23-33, 2004
The G protein-coupled receptor subset of the rat genome
DE Gloriam, R Fredriksson, HB Schiöth
BMC genomics 8, 1-17, 2007
ProteomeBinders: planning a European resource of affinity reagents for analysis of the human proteome
MJ Taussig, O Stoevesandt, CAK Borrebaeck, AR Bradbury, D Cahill, ...
Nature methods 4 (1), 13-17, 2007
5-HT2C receptor structures reveal the structural basis of GPCR polypharmacology
Y Peng, JD McCorvy, K Harpsøe, K Lansu, S Yuan, P Popov, L Qu, M Pu, ...
Cell 172 (4), 719-730. e14, 2018
GPCRdb: the G protein‐coupled receptor database–an introduction
C Munk, V Isberg, S Mordalski, K Harpsøe, K Rataj, AS Hauser, P Kolb, ...
British Journal of Pharmacology 173 (14), 2195-2207, 2016
Discovery of human signaling systems: pairing peptides to G protein-coupled receptors
SR Foster, AS Hauser, L Vedel, RT Strachan, XP Huang, AC Gavin, ...
Cell 179 (4), 895-908. e21, 2019
Structural insights into the lipid and ligand regulation of serotonin receptors
P Xu, S Huang, H Zhang, C Mao, XE Zhou, X Cheng, IA Simon, DD Shen, ...
Nature 592 (7854), 469-473, 2021
The SMARTCyp cytochrome P450 metabolism prediction server
P Rydberg, DE Gloriam, L Olsen
Bioinformatics 26 (23), 2988-2989, 2010
GPCR activation mechanisms across classes and macro/microscales
AS Hauser, AJ Kooistra, C Munk, FM Heydenreich, DB Veprintsev, ...
Nature structural & molecular biology 28 (11), 879-888, 2021
There exist at least 30 human G-protein-coupled receptors with long Ser/Thr-rich N-termini
R Fredriksson, DEI Gloriam, PJ Höglund, MC Lagerström, HB Schiöth
Biochemical and biophysical research communications 301 (3), 725-734, 2003
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