Development of a large‐scale de‐identified DNA biobank to enable personalized medicine DM Roden, JM Pulley, MA Basford, GR Bernard, EW Clayton, JR Balser, ... Clinical Pharmacology & Therapeutics 84 (3), 362-369, 2008 | 1021 | 2008 |
A sodium-channel mutation causes isolated cardiac conduction disease HL Tan, MTE Bink-Boelkens, CR Bezzina, PC Viswanathan, ... Nature 409 (6823), 1043-1047, 2001 | 516 | 2001 |
Cardiac ion channels DM Roden, JR Balser, AL George Jr, ME Anderson Annual review of physiology 64 (1), 431-475, 2002 | 450 | 2002 |
Two Distinct Congenital Arrhythmias Evoked by a Multidysfunctional Na+ Channel MW Veldkamp, PC Viswanathan, C Bezzina, A Baartscheer, AAM Wilde, ... Circulation research 86 (9), e91-e97, 2000 | 421 | 2000 |
Robust replication of genotype-phenotype associations across multiple diseases in an electronic medical record MD Ritchie, JC Denny, DC Crawford, AH Ramirez, JB Weiner, JM Pulley, ... The American Journal of Human Genetics 86 (4), 560-572, 2010 | 379 | 2010 |
A calcium sensor in the sodium channel modulates cardiac excitability HL Tan, S Kupershmidt, R Zhang, S Stepanovic, DM Roden, AAM Wilde, ... Nature 415 (6870), 442-447, 2002 | 295 | 2002 |
A common SCN5A polymorphism modulates the biophysical effects of an SCN5A mutation PC Viswanathan, DW Benson, JR Balser The Journal of clinical investigation 111 (3), 341-346, 2003 | 291 | 2003 |
Clinical, Genetic, and Biophysical Characterization of SCN5A Mutations Associated With Atrioventricular Conduction Block DW Wang, PC Viswanathan, JR Balser, AL George Jr, DW Benson Circulation 105 (3), 341-346, 2002 | 278 | 2002 |
A mutation in the human cardiac sodium channel (E161K) contributes to sick sinus syndrome, conduction disease and Brugada syndrome in two families JPP Smits, TT Koopmann, R Wilders, MW Veldkamp, T Opthof, ... Journal of molecular and cellular cardiology 38 (6), 969-981, 2005 | 265 | 2005 |
Suppression of time-dependent outward current in guinea pig ventricular myocytes. Actions of quinidine and amiodarone. JR Balser, PB Bennett, LM Hondeghem, DM Roden Circulation Research 69 (2), 519-529, 1991 | 251 | 1991 |
The cardiac sodium channel: gating function and molecular pharmacology JR Balser Journal of molecular and cellular cardiology 33 (4), 599-613, 2001 | 241 | 2001 |
Enhanced Na+ Channel Intermediate Inactivation in Brugada Syndrome DW Wang, N Makita, A Kitabatake, JR Balser, AL George Jr Circulation research 87 (8), e37-e43, 2000 | 222 | 2000 |
Radial artery pressure monitoring underestimates central arterial pressure during vasopressor therapy in critically ill surgical patients T Dorman, MJ Breslow, PA Lipsett, JM Rosenberg, JR Balser, Y Almog, ... Critical care medicine 26 (10), 1646-1649, 1998 | 222 | 1998 |
Γ-adrenergic blockade accelerates conversion of postoperative supraventricular tachyarrhythmias JR Balser, EA Martinez, BD Winters, PW Perdue, AW Clarke, W Huang, ... The Journal of the American Society of Anesthesiologists 89 (5), 1052-1059, 1998 | 205 | 1998 |
Anesthesiology physician scientists in academic medicine: a wake-up call DA Schwinn, JR Balser The Journal of the American Society of Anesthesiologists 104 (1), 170-178, 2006 | 176 | 2006 |
An EF-hand in the sodium channel couples intracellular calcium to cardiac excitability TL Wingo, VN Shah, ME Anderson, TP Lybrand, WJ Chazin, JR Balser Nature structural & molecular biology 11 (3), 219-225, 2004 | 174 | 2004 |
Oxidative mediated lipid peroxidation recapitulates proarrhythmic effects on cardiac sodium channels K Fukuda, SS Davies, T Nakajima, BH Ong, S Kupershmidt, J Fessel, ... Circulation research 97 (12), 1262-1269, 2005 | 172 | 2005 |
Phenotypic characterization of a novel long-QT syndrome mutation (R1623Q) in the cardiac sodium channel NG Kambouris, HB Nuss, DC Johns, GF Tomaselli, E Marban, JR Balser Circulation 97 (7), 640-644, 1998 | 167 | 1998 |
Time-dependent outward current in guinea pig ventricular myocytes. Gating kinetics of the delayed rectifier. JR Balser, PB Bennett, DM Roden The Journal of general physiology 96 (4), 835-863, 1990 | 163 | 1990 |
External pore residue mediates slow inactivation in mu 1 rat skeletal muscle sodium channels. JR Balser, HB Nuss, N Chiamvimonvat, MT Pérez-Garcia, E Marban, ... The Journal of physiology 494 (2), 431-442, 1996 | 160 | 1996 |