| Control of somatic tissue differentiation by the long non-coding RNA TINCR M Kretz, Z Siprashvili, C Chu, DE Webster, A Zehnder, K Qu, CS Lee, ... Nature 493 (7431), 231-235, 2013 | 980 | 2013 |
| Long intergenic noncoding RNAs: new links in cancer progression MC Tsai, RC Spitale, HY Chang Cancer research 71 (1), 3-7, 2011 | 739 | 2011 |
| Structural imprints in vivo decode RNA regulatory mechanisms RC Spitale, RA Flynn, QC Zhang, P Crisalli, B Lee, JW Jung, ... Nature 519 (7544), 486-490, 2015 | 704 | 2015 |
| Landscape and variation of RNA secondary structure across the human transcriptome Y Wan, K Qu, QC Zhang, RA Flynn, O Manor, Z Ouyang, J Zhang, ... Nature 505 (7485), 706-709, 2014 | 559 | 2014 |
| Understanding the transcriptome through RNA structure Y Wan, M Kertesz, RC Spitale, E Segal, HY Chang Nature Reviews Genetics 12 (9), 641-655, 2011 | 503 | 2011 |
| RNA SHAPE analysis in living cells RC Spitale, P Crisalli, RA Flynn, EA Torre, ET Kool, HY Chang Nature chemical biology 9 (1), 18-20, 2013 | 423 | 2013 |
| RNA helicase DDX21 coordinates transcription and ribosomal RNA processing E Calo, RA Flynn, L Martin, RC Spitale, HY Chang, J Wysocka Nature 518 (7538), 249-253, 2015 | 264 | 2015 |
| RNA templating the epigenome: long noncoding RNAs as molecular scaffolds RC Spitale, MC Tsai, HY Chang Epigenetics 6 (5), 539-543, 2011 | 232 | 2011 |
| Development of a chimeric model to study and manipulate human microglia in vivo J Hasselmann, MA Coburn, W England, DXF Velez, SK Shabestari, ... Neuron 103 (6), 1016-1033. e10, 2019 | 224 | 2019 |
| Molecular targets of aspirin and cancer prevention L Alfonso, G Ai, RC Spitale, GJ Bhat British journal of cancer 111 (1), 61-67, 2014 | 223 | 2014 |
| Age-dependent pancreatic gene regulation reveals mechanisms governing human β cell function HE Arda, L Li, J Tsai, EA Torre, Y Rosli, H Peiris, RC Spitale, C Dai, X Gu, ... Cell metabolism 23 (5), 909-920, 2016 | 217 | 2016 |
| Assessment of the genetic basis of rosacea by genome-wide association study ALS Chang, I Raber, J Xu, R Li, R Spitale, J Chen, AK Kiefer, C Tian, ... Journal of Investigative Dermatology 135 (6), 1548-1555, 2015 | 200 | 2015 |
| Tandem stem-loops in roX RNAs act together to mediate X chromosome dosage compensation in Drosophila IA Ilik, JJ Quinn, P Georgiev, F Tavares-Cadete, D Maticzka, S Toscano, ... Molecular cell 51 (2), 156-173, 2013 | 168 | 2013 |
| Technologies to probe functions and mechanisms of long noncoding RNAs C Chu, RC Spitale, HY Chang Nature structural & molecular biology 22 (1), 29-35, 2015 | 151 | 2015 |
| Transcriptome-wide interrogation of RNA secondary structure in living cells with icSHAPE RA Flynn, QC Zhang, RC Spitale, B Lee, MR Mumbach, HY Chang Nature protocols 11 (2), 273-290, 2016 | 149 | 2016 |
| Progress and challenges for chemical probing of RNA structure inside living cells M Kubota, C Tran, RC Spitale Nature chemical biology 11 (12), 933-941, 2015 | 122 | 2015 |
| The Structural Basis for Recognition of the PreQ0 Metabolite by an Unusually Small Riboswitch Aptamer Domain*♦ RC Spitale, AT Torelli, J Krucinska, V Bandarian, JE Wedekind Journal of Biological Chemistry 284 (17), 11012-11016, 2009 | 115 | 2009 |
| A biologically stable DNAzyme that efficiently silences gene expression in cells Y Wang, K Nguyen, RC Spitale, JC Chaput Nature Chemistry 13 (4), 319-326, 2021 | 109 | 2021 |
| A technology-agnostic long-read analysis pipeline for transcriptome discovery and quantification D Wyman, G Balderrama-Gutierrez, F Reese, S Jiang, S Rahmanian, ... Biorxiv, 672931, 2019 | 90 | 2019 |
| Dissecting noncoding and pathogen RNA–protein interactomes RA Flynn, L Martin, RC Spitale, BT Do, SM Sagan, B Zarnegar, K Qu, ... Rna 21 (1), 135-143, 2015 | 88 | 2015 |
