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Przemysław Karpowicz
Przemysław Karpowicz
Wydział Chemii Uniwersytet Gdański
Verified email at ug.edu.pl
Title
Cited by
Cited by
Year
The proteasome in health and disease
E Jankowska, J Stoj, P Karpowicz, PA Osmulski, M Gaczynska
Current pharmaceutical design 19 (6), 1010-1028, 2013
552013
Proline-and arginine-rich peptides as flexible allosteric modulators of human proteasome activity
M Giżyńska, J Witkowska, P Karpowicz, R Rostankowski, ES Chocron, ...
Journal of Medicinal Chemistry 62 (1), 359-370, 2018
382018
Crystal structure of a low molecular weight activator Blm-pep with yeast 20S proteasome–insights into the enzyme activation mechanism
J Witkowska, M Giżyńska, P Grudnik, P Golik, P Karpowicz, A Giełdoń, ...
Scientific Reports 7 (1), 6177, 2017
292017
Development of a peptide derived from platelet-derived growth factor (PDGF-BB) into a potential drug candidate for the treatment of wounds
M Deptuła, P Karpowicz, A Wardowska, P Sass, P Sosnowski, ...
Advances in Wound Care 9 (12), 657-675, 2020
282020
Genetic and pharmacologic proteasome augmentation ameliorates Alzheimer’s-like pathology in mouse and fly APP overexpression models
ES Chocron, E Munkácsy, HS Kim, P Karpowicz, N Jiang, CE Van Skike, ...
Science advances 8 (23), eabk2252, 2022
262022
New peptide-based pharmacophore activates 20S proteasome
PA Osmulski, P Karpowicz, E Jankowska, J Bohmann, AM Pickering, ...
Molecules 25 (6), 1439, 2020
172020
Interplay between structure and charge as a key to allosteric modulation of human 20S proteasome by the basic fragment of HIV-1 tat protein
P Karpowicz, PA Osmulski, J Witkowska, E Sikorska, M Giżyńska, ...
PLoS One 10 (11), e0143038, 2015
162015
Dissecting a role of a charge and conformation of Tat2 peptide in allosteric regulation of 20S proteasome
J Witkowska, P Karpowicz, M Gaczynska, PA Osmulski, E Jankowska
Journal of Peptide Science 20 (8), 649-656, 2014
162014
Pressure as a denaturing agent in studies of single‐point mutants of an amyloidogenic protein human cystatin c
E Jankowska, P Stefanowicz, M Sosnowska, P Karpowicz, ...
Proteins: Structure, Function, and Bioinformatics 80 (10), 2417-2425, 2012
82012
AFM Imaging Reveals Topographic Diversity of Wild Type and Z Variant Polymers of Human α1-Proteinase Inhibitor
M Gaczynska, P Karpowicz, CE Stuart, MG Norton, JH Teckman, ...
PloS one 11 (3), e0151902, 2016
72016
Peptidomimetics Based on C-Terminus of Blm10 Stimulate Human 20S Proteasome Activity and Promote Degradation of Proteins
K Cekała, K Trepczyk, D Sowik, P Karpowicz, A Giełdoń, J Witkowska, ...
Biomolecules 12 (6), 777, 2022
22022
Oligomers and peptidomimetics consisting of methyl 3-amino-2, 3-dideoxyhexopyranosiduronic acids
E Sikorska, D Tuwalska, P Karpowicz, E Jankowska, A Nowacki, ...
Tetrahedron 71 (13), 2013-2024, 2015
22015
Proteolityczny kombinat i jego regulatory
J Stój, P Karpowicz
Wiadomości chemiczne, 1097-1118, 2012
12012
Development and evaluation of RADA-PDGF2 self-assembling peptide hydrogel for enhanced skin wound healing
M Deptuła, J Sawicka, M Zawrzykraj, A Wardowska, M Kozak, ...
Frontiers in Pharmacology 14, 1293647, 2023
2023
Fragment pętli wiążącej białka VEGF-A jako potencjalny związek pro-regeneracyjny
K Polaczek, M Deptuła, M Pikuła, P Karpowicz
Faculty of Chemistry, 2022
2022
Peptide-based compositions and methods for treating alzheimer's disease
PA Osmulski, M Gaczynska, A Pickering, P Karpowicz, E Jankowska
2021
PR39-based peptidomimetics as allosteric inhibitors of proteasome activity
M Giżyńska, J Witkowska, P Karpowicz, E Jankowska
Laboratory of Medical Chemistry, 2019
2019
Determination of the binding sites of activators within the proteasome structure
M Giżyńska, J Witkowska, P Karpowicz, F Henneberg, A Chari, A Giełdoń, ...
Laboratory of Medical Chemistry, 2019
2019
Determination of the Binding Sites of Activators within the Proteasome Structure
M Gizynska, J Witkowska, P Karpowicz, F Henneberg, A Chari, A Gieldon, ...
Multidisciplinary Digital Publishing Institute Proceedings 22 (1), 99, 2019
2019
Tuning human 20S proteasome activity by proline-and arginine-rich peptides
M Giżyńska, J Witkowska, P Karpowicz, AM Pickering, P Osmulski, ...
Laboratory of Medical Chemistry, 2018
2018
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