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Anna Łęgowska
Anna Łęgowska
Unknown affiliation
Verified email at ug.edu.pl
Title
Cited by
Cited by
Year
Sunflower trypsin inhibitor 1 as a molecular scaffold for drug discovery
A Lesner, A Legowska, M Wysocka, K Rolka
Current pharmaceutical design 17 (38), 4308-4317, 2011
582011
Introduction of non-natural amino acid residues into the substrate-specific P1 position of trypsin inhibitor SFTI-1 yields potent chymotrypsin and cathepsin G inhibitors
A Łęgowska, D Dębowski, A Lesner, M Wysocka, K Rolka
Bioorganic & medicinal chemistry 17 (9), 3302-3307, 2009
542009
Examples of Peptide–Peptoid Hybrid Serine Protease Inhibitors Based on the Trypsin Inhibitor SFTI‐1 with Complete Protease Resistance at the P1 P1′ Reactive Site
M Stawikowski, R Stawikowska, A Jaśkiewicz, E Zabłotna, K Rolka
ChemBioChem 6 (6), 1057-1061, 2005
472005
Conjugates of ciprofloxacin and levofloxacin with cell-penetrating peptide exhibit antifungal activity and mammalian cytotoxicity
N Ptaszyńska, K Gucwa, K Olkiewicz, M Heldt, M Serocki, A Stupak, ...
International journal of molecular sciences 21 (13), 4696, 2020
442020
Inhibitors of Matriptase‐2 Based on the Trypsin Inhibitor SFTI‐1
A Gitlin, D Dębowski, N Karna, A Łęgowska, M Stirnberg, M Gütschow, ...
ChemBioChem 16 (11), 1601-1607, 2015
402015
Derivatization of peptides as quaternary ammonium salts for sensitive detection by ESI‐MS
M Cydzik, M Rudowska, P Stefanowicz, Z Szewczuk
Journal of peptide science 17 (6), 445-453, 2011
382011
Design of serine proteinase inhibitors by combinatorial chemistry using trypsin inhibitor SFTI‐1 as a starting structure
E Zabłotna, A Jaśkiewicz, A Łęgowska, H Miecznikowska, A Lesner, ...
Journal of peptide science: an official publication of the European Peptide …, 2007
382007
Substrate specificity and inhibitory study of human airway trypsin-like protease
M Wysocka, B Spichalska, A Lesner, M Jaros, K Brzozowski, A Łęgowska, ...
Bioorganic & medicinal chemistry 18 (15), 5504-5509, 2010
372010
Design of selective substrates of proteinase 3 using combinatorial chemistry methods
M Wysocka, A Lesner, K Guzow, L Mackiewicz, A Łęgowska, W Wiczk, ...
Analytical biochemistry 378 (2), 208-215, 2008
362008
Trypsin inhibitors from the garden four o’clock (Mirabilis jalapa) and spinach (Spinacia oleracea) seeds: isolation, characterization and chemical synthesis
J Kowalska, K Pszczoła, A Wilimowska-Pelc, I Lorenc-Kubis, E Zuziak, ...
Phytochemistry 68 (11), 1487-1496, 2007
312007
Three wavelength substrate system of neutrophil serine proteinases
M Wysocka, A Lesner, N Gruba, B Korkmaz, F Gauthier, M Kitamatsu, ...
Analytical chemistry 84 (16), 7241-7248, 2012
302012
Application of specific cell permeable cathepsin G inhibitors resulted in reduced antigen processing in primary dendritic cells
M Reich, A Lesner, A Łęgowska, M Sieńczyk, J Oleksyszyn, BO Boehm, ...
Molecular immunology 46 (15), 2994-2999, 2009
302009
Vasopressin and its analogues: from natural hormones to multitasking peptides
M Glavaš, A Gitlin-Domagalska, D Dębowski, N Ptaszyńska, A Łęgowska, ...
International journal of molecular sciences 23 (6), 3068, 2022
292022
New potent cathepsin G phosphonate inhibitors
M Sieńczyk, A Lesner, M Wysocka, A Łęgowska, E Pietrusewicz, K Rolka, ...
Bioorganic & medicinal chemistry 16 (19), 8863-8867, 2008
282008
Implication of the disulfide bridge in trypsin inhibitor SFTI-1 in its interaction with serine proteinases
A Łęgowska, D Dębowski, R Łukajtis, M Wysocka, C Czaplewski, ...
Bioorganic & medicinal chemistry 18 (23), 8188-8193, 2010
272010
Peptomeric analogues of trypsin inhibitor SFTI-1 isolated from sunflower seeds
A Łęgowska, E Bulak, M Wysocka, A Jaśkiewicz, A Lesner, D Dębowski, ...
Bioorganic & medicinal chemistry 16 (10), 5644-5652, 2008
272008
Antibiotic-based conjugates containing antimicrobial HLopt2 peptide: design, synthesis, antimicrobial and cytotoxic activities
N Ptaszyńska, K Gucwa, K Olkiewicz, A Łȩgowska, J Okońska, ...
ACS chemical biology 14 (10), 2233-2242, 2019
222019
Inhibitory and antimicrobial activities of OGTI and HV-BBI peptides, fragments and analogs derived from amphibian skin
D Dębowski, R Łukajtis, A Łęgowska, N Karna, M Pikuła, M Wysocka, ...
Peptides 35 (2), 276-284, 2012
212012
Peptide conjugates of lactoferricin analogues and antimicrobials—Design, chemical synthesis, and evaluation of antimicrobial activity and mammalian cytotoxicity
N Ptaszyńska, K Olkiewicz, J Okońska, K Gucwa, A Łęgowska, ...
Peptides 117, 170079, 2019
202019
Relationship between copper (II) complexes with FomA adhesin fragments of F. nucleatum and colorectal cancer. Coordination pattern and ability to promote ROS production
MK Lesiów, UK Komarnicka, K Stokowa-Sołtys, K Rolka, A Łęgowska, ...
Dalton Transactions 47 (15), 5445-5458, 2018
192018
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