| The methionine-aromatic motif plays a unique role in stabilizing protein structure CC Valley, A Cembran, JD Perlmutter, AK Lewis, NP Labello, J Gao, ... Journal of Biological Chemistry 287 (42), 34979-34991, 2012 | 326 | 2012 |
| EGFR ligands differentially stabilize receptor dimers to specify signaling kinetics DM Freed, NJ Bessman, A Kiyatkin, E Salazar-Cavazos, PO Byrne, ... Cell 171 (3), 683-695. e18, 2017 | 313 | 2017 |
| Differential regulation of estrogen-inducible proteolysis and transcription by the estrogen receptor α N terminus CC Valley, R Métivier, NM Solodin, AM Fowler, MT Mashek, L Hill, ... Molecular and cellular biology 25 (13), 5417-5428, 2005 | 148 | 2005 |
| Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) induces death receptor 5 networks that are highly organized CC Valley, AK Lewis, DJ Mudaliar, JD Perlmutter, AR Braun, CB Karim, ... Journal of Biological Chemistry 287 (25), 21265-21278, 2012 | 107 | 2012 |
| Enhanced dimerization drives ligand-independent activity of mutant epidermal growth factor receptor in lung cancer CC Valley, DJ Arndt-Jovin, N Karedla, MP Steinkamp, AI Chizhik, ... Molecular Biology of the Cell 26 (22), 4087-4099, 2015 | 85 | 2015 |
| Temporal variation in estrogen receptor-α protein turnover in the presence of estrogen CC Valley, NM Solodin, GL Powers, SJ Ellison, ET Alarid Journal of molecular endocrinology 40 (1), 23-34, 2008 | 71 | 2008 |
| Oxidation increases the strength of the methionine-aromatic interaction AK Lewis, KM Dunleavy, TL Senkow, C Her, BT Horn, MA Jersett, ... Nature chemical biology 12 (10), 860-866, 2016 | 62 | 2016 |
| Sequential superresolution imaging of multiple targets using a single fluorophore CC Valley, S Liu, DS Lidke, KA Lidke PloS one 10 (4), e0123941, 2015 | 59 | 2015 |
| Altered target gene regulation controlled by estrogen receptor-α concentration AM Fowler, NM Solodin, CC Valley, ET Alarid Molecular endocrinology 20 (2), 291-301, 2006 | 54 | 2006 |
| TNFR1 signaling is associated with backbone conformational changes of receptor dimers consistent with over-activation in the R92Q TRAPS mutant AK Lewis, CC Valley, JN Sachs Biochemistry, 0 | 54 | |
| NaCl interactions with phosphatidylcholine bilayers do not alter membrane structure but induce long-range ordering of ions and water CC Valley, JD Perlmutter, AR Braun, JN Sachs The Journal of Membrane Biology 244, 35-42, 2011 | 49 | 2011 |
| HuR’s post-transcriptional regulation of death receptor 5 in pancreatic cancer cells DM Pineda, DW Rittenhouse, CC Valley, JA Cozzitorto, RA Burkhart, ... Cancer biology & therapy 13 (10), 946-955, 2012 | 45 | 2012 |
| Mechanisms of inside-out signaling of the high-affinity IgG receptor FcγRI AM Brandsma, SL Schwartz, MJ Wester, CC Valley, GLA Blezer, ... Science signaling 11 (540), eaaq0891, 2018 | 39 | 2018 |
| The spatiotemporal organization of ErbB receptors: insights from microscopy CC Valley, KA Lidke, DS Lidke Cold Spring Harbor perspectives in biology 6 (2), a020735, 2014 | 36 | 2014 |
| Piecing it together: Unraveling the elusive structure-function relationship in single-pass membrane receptors CC Valley, AK Lewis, JN Sachs Biochimica et Biophysica Acta (BBA)-Biomembranes 1859 (9), 1398-1416, 2017 | 24 | 2017 |
| Death receptor 5 networks require membrane cholesterol for proper structure and function AK Lewis, CC Valley, SL Peery, B Brummel, AR Braun, CB Karim, ... Journal of molecular biology 428 (24), 4843-4855, 2016 | 21 | 2016 |
| RTK signaling requires C3ar1/C5ar1 and IL‐6R joint signaling to repress dominant PTEN, SOCS1/3 and PHLPP restraint MG Strainic, E Pohlmann, CC Valley, A Sammeta, W Hussain, DS Lidke, ... The FASEB Journal 34 (2), 2105-2125, 2020 | 8 | 2020 |
| Inside-out signaling of oncogenic EGFR mutants promotes ligand-independent dimerization CC Valley, DJ Arndt-Jovin, TM Jovin, MP Steinkamp, AI Chizhik, ... Biophysical Journal 108 (2), 351a, 2015 | 3 | 2015 |
| Mechanisms of inside-out signaling of the high-affinity IgG receptor FcgRI AM Brandsma, SL Schwartz, MJ Wester, CC Valley, GLA Blezer, ... Sci Signal 11, 2018 | 2 | 2018 |
| Oxidation Increases the Strength of the Methionine-Aromatic Interaction AK Lewis, A Cembran, TL Senkow, R Mahling, GT Perell, MR McCarthy, ... Biophysical Journal 108 (2), 17a, 2015 | 1 | 2015 |
Andrew K. LewisLuminary TherapeuticsVerified email at luminarytx.com
