Phase-plate cryo-EM structure of a class B GPCR–G-protein complex YL Liang, M Khoshouei, M Radjainia, Y Zhang, A Glukhova, J Tarrasch, ... Nature 546 (7656), 118-123, 2017 | 483 | 2017 |
Structure of the adenosine-bound human adenosine A1 receptor–Gi complex CJ Draper-Joyce, M Khoshouei, DM Thal, YL Liang, ATN Nguyen, ... Nature 558 (7711), 559-563, 2018 | 323 | 2018 |
Phase-plate cryo-EM structure of a biased agonist-bound human GLP-1 receptor–Gs complex YL Liang, M Khoshouei, A Glukhova, SGB Furness, P Zhao, L Clydesdale, ... Nature 555 (7694), 121-125, 2018 | 300 | 2018 |
Cryo-EM structure of the active, Gs-protein complexed, human CGRP receptor YL Liang, M Khoshouei, G Deganutti, A Glukhova, C Koole, TS Peat, ... Nature 561 (7724), 492-497, 2018 | 230 | 2018 |
Activation of the GLP-1 receptor by a non-peptidic agonist P Zhao, YL Liang, MJ Belousoff, G Deganutti, MM Fletcher, FS Willard, ... Nature 577 (7790), 432-436, 2020 | 131 | 2020 |
Ligand-dependent modulation of G protein conformation alters drug efficacy SGB Furness, YL Liang, CJ Nowell, ML Halls, PJ Wookey, E Dal Maso, ... Cell 167 (3), 739-749. e11, 2016 | 126 | 2016 |
Differential GLP-1R binding and activation by peptide and non-peptide agonists X Zhang, MJ Belousoff, P Zhao, AJ Kooistra, TT Truong, SY Ang, ... Molecular Cell 80 (3), 485-500. e7, 2020 | 122 | 2020 |
Toward a structural understanding of class B GPCR peptide binding and activation YL Liang, MJ Belousoff, P Zhao, C Koole, MM Fletcher, TT Truong, ... Molecular cell 77 (3), 656-668. e5, 2020 | 96 | 2020 |
Dominant negative G proteins enhance formation and purification of agonist-GPCR-G protein complexes for structure determination YL Liang, P Zhao, C Draper-Joyce, JA Baltos, A Glukhova, TT Truong, ... ACS pharmacology & translational science 1 (1), 12-20, 2018 | 93 | 2018 |
Structure and Dynamics of Adrenomedullin Receptors AM1 and AM2 Reveal Key Mechanisms in the Control of Receptor Phenotype by Receptor Activity … YL Liang, MJ Belousoff, MM Fletcher, X Zhang, M Khoshouei, G Deganutti, ... ACS pharmacology & translational science 3 (2), 263-284, 2020 | 74 | 2020 |
Structure and dynamics of the CGRP receptor in apo and peptide-bound forms TM Josephs, MJ Belousoff, YL Liang, SJ Piper, J Cao, DJ Garama, ... Science 372 (6538), eabf7258, 2021 | 65 | 2021 |
Recent advances in the determination of G protein-coupled receptor structures DM Thal, Z Vuckovic, CJ Draper-Joyce, YL Liang, A Glukhova, ... Current opinion in structural biology 51, 28-34, 2018 | 64 | 2018 |
Structure and dynamics of the active Gs-coupled human secretin receptor M Dong, G Deganutti, SJ Piper, YL Liang, M Khoshouei, MJ Belousoff, ... Nature communications 11 (1), 4137, 2020 | 49 | 2020 |
Two distinct domains of the glucagon-like peptide-1 receptor control peptide-mediated biased agonism S Lei, L Clydesdale, A Dai, X Cai, Y Feng, D Yang, YL Liang, C Koole, ... Journal of Biological Chemistry 293 (24), 9370-9387, 2018 | 49 | 2018 |
High-throughput production and structural characterization of libraries of self-assembly lipidic cubic phase materials C Darmanin, CE Conn, J Newman, X Mulet, SA Seabrook, YL Liang, ... ACS combinatorial science 14 (4), 247-252, 2012 | 46 | 2012 |
The molecular control of calcitonin receptor signaling E Dal Maso, A Glukhova, Y Zhu, J Garcia-Nafria, CG Tate, S Atanasio, ... ACS Pharmacology & Translational Science 2 (1), 31-51, 2019 | 44 | 2019 |
Routine sub-2.5 Å cryo-EM structure determination of GPCRs R Danev, M Belousoff, YL Liang, X Zhang, F Eisenstein, D Wootten, ... Nature Communications 12 (1), 4333, 2021 | 42 | 2021 |
Structural perspective of class B1 GPCR signaling Z Cong, YL Liang, Q Zhou, S Darbalaei, F Zhao, W Feng, L Zhao, HE Xu, ... Trends in Pharmacological Sciences 43 (4), 321-334, 2022 | 41 | 2022 |
Dynamics of GLP-1R peptide agonist engagement are correlated with kinetics of G protein activation G Deganutti, YL Liang, X Zhang, M Khoshouei, L Clydesdale, ... Nature Communications 13 (1), 92, 2022 | 40 | 2022 |
A structural basis for amylin receptor phenotype J Cao, MJ Belousoff, YL Liang, RM Johnson, TM Josephs, MM Fletcher, ... Science 375 (6587), eabm9609, 2022 | 34 | 2022 |