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Shamith Samarajiwa
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The genomic and transcriptomic architecture of 2,000 breast tumours reveals novel subgroups
C Curtis, SP Shah, SF Chin, G Turashvili, OM Rueda, MJ Dunning, ...
Nature 486 (7403), 346-352, 2012
50032012
Type I interferon receptors: biochemistry and biological functions
NA De Weerd, SA Samarajiwa, PJ Hertzog
Journal of Biological Chemistry 282 (28), 20053-20057, 2007
4672007
Spatial coupling of mTOR and autophagy augments secretory phenotypes
M Narita, ARJ Young, S Arakawa, SA Samarajiwa, T Nakashima, ...
Science 332 (6032), 966-70, 2011
4652011
Silencing of Irf7 pathways in breast cancer cells promotes bone metastasis through immune escape
BN Bidwell, CY Slaney, NP Withana, S Forster, Y Cao, S Loi, D Andrews, ...
Nature Medicine, 2012
4212012
A re-annotation pipeline for Illumina BeadArrays: improving the interpretation of gene expression data
NL Barbosa-Morais, MJ Dunning, SA Samarajiwa, JFJ Darot, ME Ritchie, ...
Nucleic acids research 38 (3), e17-e17, 2010
2782010
INTERFEROME: the database of interferon regulated genes
SA Samarajiwa, S Forster, K Auchettl, PJ Hertzog
Nucleic acids research 37 (suppl_1), D852-D857, 2009
2582009
Independence of Repressive Histone Marks and Chromatin Compaction during Senescent Heterochromatic Layer Formation
T Chandra, K Kirschner, JY Thuret, BD Pope, T Ryba, S Newman, ...
Molecular Cell, 2012
2552012
Systems biology of interferon responses
P Hertzog, S Forster, S Samarajiwa
Journal of Interferon & Cytokine Research 31 (1), 5-11, 2011
1452011
ZNF703 is a common Luminal B breast cancer oncogene that differentially regulates luminal and basal progenitors in human mammary epithelium
DG Holland, A Burleigh, A Git, MA Goldgraben, PA Perez‐Mancera, ...
EMBO molecular medicine 3 (3), 167-180, 2011
1262011
HIV infection of dendritic cells subverts the IFN induction pathway via IRF-1 and inhibits type 1 IFN production
AN Harman, J Lai, S Turville, S Samarajiwa, L Gray, V Marsden, ...
Blood, The Journal of the American Society of Hematology 118 (2), 298-308, 2011
1232011
Lung tumors with distinct p53 mutations respond similarly to p53 targeted therapy but exhibit genotype-specific statin sensitivity.
MCP Turrell FK, Kerr EM, Gao M, Thorpe H, Doherty GJ, Cridge J, Shorthouse D ...
Genes Dev., 2017
552017
A KLF6-driven transcriptional network links lipid homeostasis and tumour growth in renal carcinoma
SE Syafruddin, P Rodrigues, E Vojtasova, SA Patel, MN Zaini, J Burge, ...
Nature communications 10 (1), 1-13, 2019
492019
A tumor DNA complex aberration index is an independent predictor of survival in breast and ovarian cancer.
KVN Vollan HK, Rueda OM, Chin SF, Curtis C, Turashvili G, Shah S, Lingjærde ...
Mol Oncol., 2015
492015
NOTCH-mediated non-cell autonomous regulation of chromatin structure during senescence
AJ Parry, M Hoare, D Bihary, R Hänsel-Hertsch, S Smith, K Tomimatsu, ...
Nature communications 9 (1), 1-15, 2018
452018
Phenotype Specific Analyses Reveal Distinct Regulatory Mechanism for Chronically Activated p53.
Kirschner K, Samarajiwa SA, Cairns JM, Menon S, Pérez-Mancera PA, Tomimatsu ...
PLoS Genet. 11 (3), 2015
452015
NF-κB–Dependent Lymphoid Enhancer Co-option Promotes Renal Carcinoma MetastasisCross-Lineage Enhancer Co-option Promotes RCC Metastasis
P Rodrigues, SA Patel, L Harewood, I Olan, E Vojtasova, SE Syafruddin, ...
Cancer discovery 8 (7), 850-865, 2018
312018
Soluble IFN Receptor Potentiates In Vivo Type I IFN Signaling and Exacerbates TLR4-Mediated Septic Shock.
SA Samarajiwa, NE Mangan, MP Hardy, ...
J Immunol, 2014
282014
Effects of BRCA2 cis-regulation in normal breast and cancer risk amongst BRCA2 mutation carriers
AT Maia, AC Antoniou, M O'Reilly, S Samarajiwa, M Dunning, ...
Breast cancer research 14 (2), 1-15, 2012
242012
Transcription-driven cohesin repositioning rewires chromatin loops in cellular senescence
I Olan, AJ Parry, S Schoenfelder, M Narita, Y Ito, ASL Chan, G Slater, ...
bioRxiv, 2019
23*2019
Transcription-dependent cohesin repositioning rewires chromatin loops in cellular senescence
Ioana Olan, Aled J. Parry, Stefan Schoenfelder, Masako Narita, Yoko Ito ...
Nature Communications 11 (6049), 2020
212020
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