Emergence of KRAS mutations and acquired resistance to anti-EGFR therapy in colorectal cancer S Misale, R Yaeger, S Hobor, E Scala, M Janakiraman, D Liska, E Valtorta, ... Nature 486 (7404), 532-536, 2012 | 1883 | 2012 |
Clonal evolution and resistance to EGFR blockade in the blood of colorectal cancer patients G Siravegna, B Mussolin, M Buscarino, G Corti, A Cassingena, ... Nature medicine 21 (7), 795-801, 2015 | 1002 | 2015 |
A Molecularly Annotated Platform of Patient-Derived Xenografts (“Xenopatients”) Identifies HER2 as an Effective Therapeutic Target in Cetuximab-Resistant Colorectal CancerHER2 … A Bertotti, G Migliardi, F Galimi, F Sassi, D Torti, C Isella, D Corà, ... Cancer discovery 1 (6), 508-523, 2011 | 931 | 2011 |
Expression of the Met/HGF receptor in normal and neoplastic human tissues. MF Di Renzo, RP Narsimhan, M Olivero, S Bretti, S Giordano, E Medico, ... Oncogene 6 (11), 1997-2003, 1991 | 631 | 1991 |
FLAME, a novel fuzzy clustering method for the analysis of DNA microarray data L Fu, E Medico BMC bioinformatics 8 (1), 1-15, 2007 | 594 | 2007 |
Stromal contribution to the colorectal cancer transcriptome C Isella, A Terrasi, SE Bellomo, C Petti, G Galatola, A Muratore, A Mellano, ... Nature genetics 47 (4), 312-319, 2015 | 583 | 2015 |
Interrogating open issues in cancer precision medicine with patient-derived xenografts AT Byrne, DG Alférez, F Amant, D Annibali, J Arribas, AV Biankin, A Bruna, ... Nature Reviews Cancer 17 (4), 254-268, 2017 | 575 | 2017 |
Induction of MET by ionizing radiation and its role in radioresistance and invasive growth of cancer F De Bacco, P Luraghi, E Medico, G Reato, F Girolami, T Perera, ... JNCI: Journal of the National Cancer Institute 103 (8), 645-661, 2011 | 355 | 2011 |
The MET oncogene drives a genetic programme linking cancer to haemostasis C Boccaccio, G Sabatino, E Medico, F Girolami, A Follenzi, G Reato, ... Nature 434 (7031), 396-400, 2005 | 314 | 2005 |
The molecular landscape of colorectal cancer cell lines unveils clinically actionable kinase targets E Medico, M Russo, G Picco, C Cancelliere, E Valtorta, G Corti, ... Nature communications 6 (1), 7002, 2015 | 259 | 2015 |
Neural differentiation of human mesenchymal stem cells: Evidence for expression of neural markers and eag K+ channel types K Mareschi, M Novara, D Rustichelli, I Ferrero, D Guido, E Carbone, ... Experimental hematology 34 (11), 1563-1572, 2006 | 231 | 2006 |
Selective analysis of cancer-cell intrinsic transcriptional traits defines novel clinically relevant subtypes of colorectal cancer C Isella, F Brundu, SE Bellomo, F Galimi, E Zanella, R Porporato, C Petti, ... Nature communications 8 (1), 15107, 2017 | 220 | 2017 |
Promoter trapping reveals significant differences in integration site selection between MLV and HIV vectors in primary hematopoietic cells M De Palma, E Montini, FRS De Sio, F Benedicenti, A Gentile, E Medico, ... Blood 105 (6), 2307-2315, 2005 | 208 | 2005 |
Phosphorylation of serine 985 negatively regulates the hepatocyte growth factor receptor kinase. L Gandino, P Longati, E Medico, M Prat, PM Comoglio Journal of Biological Chemistry 269 (3), 1815-1820, 1994 | 191 | 1994 |
Transfer of motogenic and invasive response to scatter factor/hepatocyte growth factor by transfection of human MET protooncogene. S Giordano, Z Zhen, E Medico, G Gaudino, F Galimi, PM Comoglio Proceedings of the National Academy of Sciences 90 (2), 649-653, 1993 | 185 | 1993 |
Increased lactate secretion by cancer cells sustains non-cell-autonomous adaptive resistance to MET and EGFR targeted therapies M Apicella, E Giannoni, S Fiore, KJ Ferrari, D Fernández-Pérez, C Isella, ... Cell metabolism 28 (6), 848-865. e6, 2018 | 180 | 2018 |
Gene expression profiling uncovers molecular classifiers for the recognition of anaplastic large-cell lymphoma within peripheral T-cell neoplasms R Piva, L Agnelli, E Pellegrino, K Todoerti, V Grosso, I Tamagno, ... J Clin Oncol 28 (9), 1583-1590, 2010 | 174 | 2010 |
The tyrosine kinase receptors Ron and Sea control" scattering" and morphogenesis of liver progenitor cells in vitro. E Medico, AM Mongiovi, J Huff, MA Jelinek, A Follenzi, G Gaudino, ... Molecular biology of the cell 7 (4), 495-504, 1996 | 173 | 1996 |
The MET Oncogene Is a Functional Marker of a Glioblastoma Stem Cell SubtypeMet Is a Functional Marker of Glioblastoma Stem Cells F De Bacco, E Casanova, E Medico, S Pellegatta, F Orzan, R Albano, ... Cancer research 72 (17), 4537-4550, 2012 | 151 | 2012 |
The clinical and biological significance of MIR-224 expression in colorectal cancer metastasis H Ling, K Pickard, C Ivan, C Isella, M Ikuo, R Mitter, R Spizzo, MD Bullock, ... Gut 65 (6), 977-989, 2016 | 147 | 2016 |