Drug repurposing and human parasitic protozoan diseases KT Andrews, G Fisher, TS Skinner-Adams International Journal for Parasitology: Drugs and Drug Resistance 4 (2), 95-111, 2014 | 452 | 2014 |
Structural basis for the inhibition of the essential Plasmodium falciparum M1 neutral aminopeptidase S McGowan, CJ Porter, J Lowther, CM Stack, SJ Golding, ... Proceedings of the National Academy of Sciences 106 (8), 2537-2542, 2009 | 182 | 2009 |
Antiretrovirals as antimalarial agents TS Skinner-Adams, JS McCarthy, DL Gardiner, PM Hilton, KT Andrews The Journal of infectious diseases 190 (11), 1998-2000, 2004 | 175 | 2004 |
In vitro stage-specific sensitivity of Plasmodium falciparum to quinine and artemisinin drugs T Skinner, LS Manning, WA Johnston, TM Davis Int. J. Parasitol. 26 (5), 519-525, 1996 | 171 | 1996 |
Potencies of Human Immunodeficiency Virus Protease Inhibitors In Vitro against Plasmodium falciparum and In Vivo against Murine Malaria KT Andrews, DP Fairlie, PK Madala, J Ray, DM Wyatt, PM Hilton, ... Antimicrobial agents and chemotherapy 50 (2), 639-648, 2006 | 168 | 2006 |
Characterization of the Plasmodium falciparum M17 leucyl aminopeptidase: a protease involved in amino acid regulation with potential for antimalarial drug development CM Stack, J Lowther, E Cunningham, S Donnelly, DL Gardiner, ... Journal of Biological Chemistry 282 (3), 2069-2080, 2007 | 161 | 2007 |
Potent antimalarial activity of histone deacetylase inhibitor analogues KT Andrews, TN Tran, AJ Lucke, P Kahnberg, GT Le, GM Boyle, ... Antimicrobial agents and chemotherapy 52 (4), 1454-1461, 2008 | 156 | 2008 |
Inhibition of hypoxanthine-guanine phosphoribosyltransferase by acyclic nucleoside phosphonates: a new class of antimalarial therapeutics DT Keough, D Hockova, A Holy, LMJ Naesens, TS Skinner-Adams, ... Journal of medicinal chemistry 52 (14), 4391-4399, 2009 | 154 | 2009 |
Plasmodium falciparum neutral aminopeptidases: new targets for anti-malarials TS Skinner-Adams, CM Stack, KR Trenholme, CL Brown, J Grembecka, ... Trends in Biochemical Sciences 35 (1), 53-61, 2010 | 153 | 2010 |
Effect of Antimalarial Drugs on Plasmodium falciparum Gametocytes CL Peatey, TS Skinner-Adams, MWA Dixon, JS McCarthy, DL Gardiner, ... The Journal of infectious diseases 200 (10), 1518-1521, 2009 | 135 | 2009 |
Identification of Phosphinate Dipeptide Analog Inhibitors Directed against the Plasmodium falciparum M17 Leucine Aminopeptidase as Lead Antimalarial … TS Skinner-Adams, J Lowther, F Teuscher, CM Stack, J Grembecka, ... Journal of Medicinal Chemistry 50 (24), 6024-6031, 2007 | 114 | 2007 |
A novel Plasmodium falciparum ring stage protein, REX, is located in Maurer’s clefts PL Hawthorne, KR Trenholme, TS Skinner-Adams, T Spielmann, ... Molecular and biochemical parasitology 136 (2), 181-189, 2004 | 113 | 2004 |
Effect of clinically approved HDAC inhibitors on Plasmodium, Leishmania and Schistosoma parasite growth MJ Chua, MSJ Arnold, W Xu, J Lancelot, S Lamotte, GF Späth, E Prina, ... International Journal for Parasitology: Drugs and Drug Resistance 7 (1), 42-50, 2017 | 110 | 2017 |
Profiling the anti-protozoal activity of anti-cancer HDAC inhibitors against Plasmodium and Trypanosoma parasites A Engel, Jones, Avery, Sumanadasa, Ng, Fairli, Adams Int J Parasitol Drugs Drug Resist 5 (3), 117-26, 2015 | 104 | 2015 |
Structure of the Plasmodium falciparum M17 aminopeptidase and significance for the design of drugs targeting the neutral exopeptidases S McGowan, CA Oellig, WA Birru, TT Caradoc-Davies, CM Stack, ... Proceedings of the National Academy of Sciences 107 (6), 2449-2454, 2010 | 102 | 2010 |
HIV and malaria co-infection: interactions and consequences of chemotherapy TS Skinner-Adams, JS McCarthy, DL Gardiner, KT Andrews Trends in parasitology 24 (6), 264-271, 2008 | 97 | 2008 |
Antimalarial activity of the anticancer histone deacetylase inhibitor SB939 SDM Sumanadasa, CD Goodman, AJ Lucke, T Skinner-Adams, I Sahama, ... Antimicrobial agents and chemotherapy 56 (7), 3849-3856, 2012 | 94 | 2012 |
Fingerprinting the substrate specificity of M1 and M17 aminopeptidases of human malaria, Plasmodium falciparum M Poreba, S McGowan, TS Skinner-Adams, KR Trenholme, DL Gardiner, ... PLoS One 7 (2), e31938, 2012 | 87 | 2012 |
Drug resistance in Giardia: Mechanisms and alternative treatments for Giardiasis R Argüello-García, D Leitsch, T Skinner-Adams, MG Ortega-Pierres Advances in parasitology 107, 201-282, 2020 | 85 | 2020 |
Overexpression of leucyl aminopeptidase in Plasmodium falciparum parasites: target for the antimalarial activity of bestatin DL Gardiner, KR Trenholme, TS Skinner-Adams, CM Stack, JP Dalton Journal of Biological Chemistry 281 (3), 1741-1745, 2006 | 78 | 2006 |