| Dendritic function of tau mediates amyloid-β toxicity in Alzheimer's disease mouse models LM Ittner, YD Ke, F Delerue, M Bi, A Gladbach, J van Eersel, H Wölfing, ... Cell 142 (3), 387-397, 2010 | 2058 | 2010 |
| Sodium selenate mitigates tau pathology, neurodegeneration, and functional deficits in Alzheimer's disease models J Van Eersel, YD Ke, X Liu, F Delerue, JJ Kril, J Götz, LM Ittner Proceedings of the National Academy of Sciences 107 (31), 13888-13893, 2010 | 313 | 2010 |
| Site-specific phosphorylation of tau inhibits amyloid-β toxicity in Alzheimer’s mice A Ittner, SW Chua, J Bertz, A Volkerling, J Van Der Hoven, A Gladbach, ... Science 354 (6314), 904-908, 2016 | 273 | 2016 |
| Neuronal microRNA deregulation in response to Alzheimer's disease amyloid-β N Schonrock, YD Ke, D Humphreys, M Staufenbiel, LM Ittner, T Preiss, ... PloS one 5 (6), e11070, 2010 | 257 | 2010 |
| Parkinsonism and impaired axonal transport in a mouse model of frontotemporal dementia LM Ittner, T Fath, YD Ke, M Bi, J Van Eersel, KM Li, P Gunning, J Götz Proceedings of the National Academy of Sciences 105 (41), 15997-16002, 2008 | 243 | 2008 |
| Experimental diabetes mellitus exacerbates tau pathology in a transgenic mouse model of Alzheimer's disease YD Ke, F Delerue, A Gladbach, J Götz, LM Ittner PloS one 4 (11), e7917, 2009 | 224 | 2009 |
| Primary support cultures of hippocampal and substantia nigra neurons T Fath, YD Ke, P Gunning, J Götz, LM Ittner Nature protocols 4 (1), 78-85, 2009 | 223 | 2009 |
| A decade of tau transgenic animal models and beyond J Götz, N Deters, A Doldissen, L Bokhari, Y Ke, A Wiesner, N Schonrock, ... Brain Pathology 17 (1), 91-103, 2007 | 207 | 2007 |
| Phosphorylated Tau interacts with c-Jun N-terminal kinase-interacting protein 1 (JIP1) in Alzheimer disease LM Ittner, YD Ke, J Götz Journal of Biological Chemistry 284 (31), 20909-20916, 2009 | 192 | 2009 |
| Tau-targeted immunization impedes progression of neurofibrillary histopathology in aged P301L tau transgenic mice M Bi, A Ittner, YD Ke, J Götz, LM Ittner PloS one 6 (12), e26860, 2011 | 187 | 2011 |
| Lessons from tau-deficient mice YD Ke, AK Suchowerska, J Van Der Hoven, DM De Silva, CW Wu, ... International journal of Alzheimer’s disease 2012, 2012 | 162 | 2012 |
| Tau exacerbates excitotoxic brain damage in an animal model of stroke M Bi, A Gladbach, J Van Eersel, A Ittner, M Przybyla, A Van Hummel, ... Nature communications 8 (1), 473, 2017 | 153 | 2017 |
| Cytoplasmic accumulation and aggregation of TDP-43 upon proteasome inhibition in cultured neurons J van Eersel, YD Ke, A Gladbach, M Bi, J Götz, JJ Kril, LM Ittner PloS one 6 (7), e22850, 2011 | 135 | 2011 |
| ALS/FTLD: experimental models and reality RH Tan, YD Ke, LM Ittner, GM Halliday Acta neuropathologica 133 (2), 177-196, 2017 | 113 | 2017 |
| Tau-mediated nuclear depletion and cytoplasmic accumulation of SFPQ in Alzheimer's and Pick's disease Y Ke, J Dramiga, U Schütz, JJ Kril, LM Ittner, H Schröder, J Götz PloS one 7 (4), e35678, 2012 | 106 | 2012 |
| Physiological changes in neurodegeneration—mechanistic insights and clinical utility RM Ahmed, YD Ke, S Vucic, LM Ittner, W Seeley, JR Hodges, O Piguet, ... Nature Reviews Neurology 14 (5), 259-271, 2018 | 87 | 2018 |
| Aβ-dependent reduction of NCAM2-mediated synaptic adhesion contributes to synapse loss in Alzheimer’s disease I Leshchyns’ ka, HT Liew, C Shepherd, GM Halliday, CH Stevens, YD Ke, ... Nature communications 6 (1), 8836, 2015 | 84 | 2015 |
| TDP-43 mutations causing amyotrophic lateral sclerosis are associated with altered expression of RNA-binding protein hnRNP K and affect the Nrf2 antioxidant pathway D Moujalled, A Grubman, K Acevedo, S Yang, YD Ke, DM Moujalled, ... Human Molecular Genetics 26 (9), 1732-1746, 2017 | 78 | 2017 |
| Tau downregulates BDNF expression in animal and cellular models of Alzheimer's disease E Rosa, S Mahendram, YD Ke, LM Ittner, SD Ginsberg, M Fahnestock Neurobiology of aging 48, 135-142, 2016 | 77 | 2016 |
| Short-term suppression of A315T mutant human TDP-43 expression improves functional deficits in a novel inducible transgenic mouse model of FTLD-TDP and ALS YD Ke, A van Hummel, CH Stevens, A Gladbach, S Ippati, M Bi, WS Lee, ... Acta neuropathologica 130, 661-678, 2015 | 77 | 2015 |
