Richard I. Morimoto
Richard I. Morimoto
Bill and Gayle Cook Professor of Biology, Dept of Molecular Biosciences, Northwestern
Verified email at northwestern.edu - Homepage
Title
Cited by
Cited by
Year
Regulation of the heat shock transcriptional response: cross talk between a family of heat shock factors, molecular chaperones, and negative regulators
RI Morimoto
Genes & development 12 (24), 3788-3796, 1998
21161998
Adapting proteostasis for disease intervention
WE Balch, RI Morimoto, A Dillin, JW Kelly
science 319 (5865), 916-919, 2008
21052008
Heat-shock protein 70 inhibits apoptosis by preventing recruitment of procaspase-9 to the Apaf-1 apoptosome
HM Beere, BB Wolf, K Cain, DD Mosser, A Mahboubi, T Kuwana, P Tailor, ...
Nature cell biology 2 (8), 469-475, 2000
17682000
Cells in stress: transcriptional activation of heat shock genes
RI Morimoto
SCIENCE-NEW YORK THEN WASHINGTON- 259, 1409-1409, 1993
16551993
Heat shock factors: integrators of cell stress, development and lifespan
M Åkerfelt, RI Morimoto, L Sistonen
Nature reviews Molecular cell biology 11 (8), 545-555, 2010
12302010
Role of the heat shock response and molecular chaperones in oncogenesis and cell death
C Jolly, RI Morimoto
Journal of the National Cancer Institute 92 (19), 1564-1572, 2000
12252000
The biology of heat shock proteins and molecular chaperones
RI Morimoto, A Tissières
1222*1994
Biological and chemical approaches to diseases of proteostasis deficiency
ET Powers, RI Morimoto, A Dillin, JW Kelly, WE Balch
Annual review of biochemistry 78, 959-991, 2009
11102009
Conserved features of eukaryotic hsp70 genes revealed by comparison with the nucleotide sequence of human hsp70
C Hunt, RI Morimoto
Proceedings of the National Academy of Sciences 82 (19), 6455-6459, 1985
10011985
Activation of heat shock gene transcription by heat shock factor 1 involves oligomerization, acquisition of DNA-binding activity, and nuclear localization and can occur in the†…
KD Sarge, SP Murphy, RI Morimoto
Molecular and cellular biology 13 (3), 1392-1407, 1993
9971993
Geroscience: linking aging to chronic disease
BK Kennedy, SL Berger, A Brunet, J Campisi, AM Cuervo, ES Epel, ...
Cell 159 (4), 709-713, 2014
9912014
Proteotoxic stress and inducible chaperone networks in neurodegenerative disease and aging
RI Morimoto
Genes & development 22 (11), 1427-1438, 2008
9102008
The chaperone function of hsp70 is required for protection against stress-induced apoptosis
DD Mosser, AW Caron, L Bourget, AB Meriin, MY Sherman, RI Morimoto, ...
Molecular and cellular biology 20 (19), 7146-7159, 2000
8462000
The threshold for polyglutamine-expansion protein aggregation and cellular toxicity is dynamic and influenced by aging in Caenorhabditis elegans
JF Morley, HR Brignull, JJ Weyers, RI Morimoto
Proceedings of the National Academy of Sciences 99 (16), 10417-10422, 2002
7832002
Chaperoning signaling pathways: molecular chaperones as stress-sensingheat shock'proteins
EAA Nollen, RI Morimoto
Journal of cell science 115 (14), 2809-2816, 2002
7802002
The biology of proteostasis in aging and disease
J Labbadia, RI Morimoto
Annual review of biochemistry 84, 435-464, 2015
7652015
Regulation of Longevity in Caenorhabditis elegans by Heat Shock Factor and Molecular Chaperones
JF Morley, RI Morimoto
Molecular biology of the cell 15 (2), 657-664, 2004
7372004
Molecularchaperones as HSF1-specific transcriptional repressors
Y Shi, DD Mosser, RI Morimoto
Genes & development 12 (5), 654-666, 1998
7071998
Stress–inducible responses and heat shock proteins: new pharmacologic targets for cytoprotection
RI Morimoto, MG Santoro
Nature biotechnology 16 (9), 833-838, 1998
6981998
Complementary signaling pathways regulate the unfolded protein response and are required for C. elegans development
X Shen, RE Ellis, K Lee, CY Liu, K Yang, A Solomon, H Yoshida, ...
Cell 107 (7), 893-903, 2001
6862001
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