| A common phosphate binding site explains the unique substrate specificity of GSK3 and its inactivation by phosphorylation S Frame, P Cohen, RM Biondi Molecular cell 7 (6), 1321-1327, 2001 | 858 | 2001 |
| Signalling specificity of Ser/Thr protein kinases through docking-site-mediated interactions RM Biondi, A Nebreda Biochem. J 372, 1-13, 2003 | 471 | 2003 |
| The PIF‐binding pocket in PDK1 is essential for activation of S6K and SGK, but not PKB RM Biondi, A Kieloch, RA Currie, M Deak, DR Alessi The EMBO journal, 2001 | 450 | 2001 |
| Identification of a pocket in the PDK1 kinase domain that interacts with PIF and the C-terminal residues of PKA RM Biondi, PCF Cheung, A Casamayor, M Deak, RA Currie, DR Alessi The EMBO journal 19 (5), 979-988, 2000 | 361 | 2000 |
| A phosphoserine/threonine‐binding pocket in AGC kinases and PDK1 mediates activation by hydrophobic motif phosphorylation M Frödin, TL Antal, BA Dümmler, CJ Jensen, M Deak, S Gammeltoft, ... The EMBO journal, 2002 | 333 | 2002 |
| High resolution crystal structure of the human PDK1 catalytic domain defines the regulatory phosphopeptide docking site RM Biondi, D Komander, CC Thomas, JM Lizcano, M Deak, DR Alessi, ... The EMBO journal 21 (16), 4219-4228, 2002 | 251 | 2002 |
| A 3-phosphoinositide-dependent protein kinase-1 (PDK1) docking site is required for the phosphorylation of protein kinase Cζ (PKCζ) and PKC-related kinase 2 by PDK1 A Balendran, RM Biondi, PCF Cheung, A Casamayor, M Deak, DR Alessi Journal of Biological Chemistry 275 (27), 20806-20813, 2000 | 240 | 2000 |
| AGC protein kinases: from structural mechanism of regulation to allosteric drug development for the treatment of human diseases JM Arencibia, D Pastor-Flores, AF Bauer, JO Schulze, RM Biondi Biochimica et Biophysica Acta (BBA)-Proteins and Proteomics 1834 (7), 1302-1321, 2013 | 210 | 2013 |
| Differential stability of cell-free circulating microRNAs: implications for their utilization as biomarkers V Köberle, T Pleli, C Schmithals, E Augusto Alonso, J Haupenthal, ... PloS one 8 (9), e75184, 2013 | 208 | 2013 |
| Phosphoinositide-regulated kinases and phosphoinositide phosphatases NR Leslie, RM Biondi, DR Alessi Chemical reviews 101 (8), 2365-2380, 2001 | 161 | 2001 |
| Epac activation converts cAMP from a proliferative into a differentiation signal in PC12 cells S Kiermayer, RM Biondi, J Imig, G Plotz, J Haupenthal, S Zeuzem, ... Molecular biology of the cell 16 (12), 5639-5648, 2005 | 149 | 2005 |
| Phosphoinositide-dependent protein kinase 1, a sensor of protein conformation RM Biondi Trends in biochemical sciences 29 (3), 136-142, 2004 | 138 | 2004 |
| Mechanism for activation of the growth factor‐activated AGC kinases by turn motif phosphorylation C Hauge, TL Antal, D Hirschberg, U Doehn, K Thorup, L Idrissova, ... The EMBO journal 26 (9), 2251-2261, 2007 | 135 | 2007 |
| Structure and allosteric effects of low-molecular-weight activators on the protein kinase PDK1 V Hindie, A Stroba, H Zhang, LA Lopez-Garcia, L Idrissova, S Zeuzem, ... Nature chemical biology 5 (10), 758-764, 2009 | 134 | 2009 |
| AGC kinases, mechanisms of regulation and innovative drug development AE Leroux, JO Schulze, RM Biondi Seminars in cancer biology 48, 1-17, 2018 | 124 | 2018 |
| Allosteric activation of the protein kinase PDK1 with low molecular weight compounds M Engel, V Hindie, LA Lopez‐Garcia, A Stroba, F Schaeffer, I Adrian, ... The EMBO journal 25 (23), 5469-5480, 2006 | 124 | 2006 |
| Cellular phosphorylation of anti-HIV nucleosides: role of nucleoside diphosphate kinase J Bourdais, R Biondi, S Sarfati, C Guerreiro, I Lascu, J Janin, M Véron Journal of Biological Chemistry 271 (14), 7887-7890, 1996 | 121 | 1996 |
| 3, 5-Diphenylpent-2-enoic Acids as Allosteric Activators of the Protein Kinase PDK1: Structure− Activity Relationships and Thermodynamic Characterization of Binding as … A Stroba, F Schaeffer, V Hindie, L Lopez-Garcia, I Adrian, W Fröhner, ... Journal of medicinal chemistry 52 (15), 4683-4693, 2009 | 106 | 2009 |
| Mutations in the MutSα interaction interface of MLH1 can abolish DNA mismatch repair G Plotz, C Welsch, L Giron-Monzon, P Friedhoff, M Albrecht, A Piiper, ... Nucleic acids research 34 (22), 6574-6586, 2006 | 87 | 2006 |
| Substrate-selective inhibition of protein kinase PDK1 by small compounds that bind to the PIF-pocket allosteric docking site K Busschots, LA Lopez-Garcia, C Lammi, A Stroba, S Zeuzem, A Piiper, ... Chemistry & biology 19 (9), 1152-1163, 2012 | 84 | 2012 |
Antonio CasamayorDept. Bioquímica i Biol. Molecular. Universitat Autňnoma de BarcelonaVerified email at uab.es
