Replication stress links structural and numerical cancer chromosomal instability RA Burrell, SE McClelland, D Endesfelder, P Groth, MC Weller, N Shaikh, ... Nature 494 (7438), 492-496, 2013 | 945 | 2013 |
Tolerance of whole-genome doubling propagates chromosomal instability and accelerates cancer genome evolution SM Dewhurst, N McGranahan, RA Burrell, AJ Rowan, E Grönroos, ... Cancer discovery 4 (2), 175-185, 2014 | 448 | 2014 |
Pervasive chromosomal instability and karyotype order in tumour evolution TBK Watkins, EL Lim, M Petkovic, S Elizalde, NJ Birkbak, GA Wilson, ... Nature 587 (7832), 126-132, 2020 | 306 | 2020 |
Cancer: evolution within a lifetime M Gerlinger, N McGranahan, SM Dewhurst, RA Burrell, I Tomlinson, ... Annual review of genetics 48 (1), 215-236, 2014 | 244 | 2014 |
Interplay between whole-genome doubling and the accumulation of deleterious alterations in cancer evolution S López, EL Lim, S Horswell, K Haase, A Huebner, M Dietzen, ... Nature genetics 52 (3), 283-293, 2020 | 209 | 2020 |
Distinct classes of complex structural variation uncovered across thousands of cancer genome graphs K Hadi, X Yao, JM Behr, A Deshpande, C Xanthopoulakis, H Tian, ... Cell 183 (1), 197-210. e32, 2020 | 190 | 2020 |
APC/C dysfunction limits excessive cancer chromosomal instability L Sansregret, JO Patterson, S Dewhurst, C López-García, A Koch, ... Cancer discovery 7 (2), 218-233, 2017 | 111 | 2017 |
Oncogenic PIK3CA induces centrosome amplification and tolerance to genome doubling IM Berenjeno, R Piñeiro, SD Castillo, W Pearce, N McGranahan, ... Nature communications 8 (1), 1773, 2017 | 70 | 2017 |
Cyclin D mediates tolerance of genome-doubling in cancers with functional p53 A Crockford, LP Zalmas, E Grönroos, SM Dewhurst, N McGranahan, ... Annals of Oncology 28 (1), 149-156, 2017 | 51 | 2017 |
Structural variant evolution after telomere crisis SM Dewhurst, X Yao, J Rosiene, H Tian, J Behr, N Bosco, KK Takai, ... Nature communications 12 (1), 2093, 2021 | 23 | 2021 |
Chromothripsis and telomere crisis: engines of genome instability SM Dewhurst Current opinion in genetics & development 60, 41-47, 2020 | 18 | 2020 |
Tetraploidy and CIN: a dangerous combination S Dewhurst, C Swanton Cell Cycle 14 (20), 3217-3217, 2015 | 8 | 2015 |
Whole genome doubling mitigates muller’s ratchet in cancer evolution S López, E Lim, A Huebner, M Dietzen, T Mourikis, TBK Watkins, ... bioRxiv, 513457, 2019 | 7 | 2019 |
Whole genome doubling propagates chromosomal instability and accelerates cancer genome evolution SM Dewhurst UCL (University College London), 2015 | 1 | 2015 |