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Marcin Warmiński
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The identity and methylation status of the first transcribed nucleotide in eukaryotic mRNA 5′ cap modulates protein expression in living cells
PJ Sikorski, M Warminski, D Kubacka, T Ratajczak, D Nowis, J Kowalska, ...
Nucleic Acids Research 48 (4), 1607-1626, 2020
882020
5′-phosphorothiolate dinucleotide cap analogues: Reagents for messenger RNA modification and potent small-molecular inhibitors of decapping enzymes
BA Wojtczak, PJ Sikorski, K Fac-Dabrowska, A Nowicka, M Warminski, ...
Journal of the American Chemical Society 140 (18), 5987-5999, 2018
732018
Applications of phosphate modification and labeling to study (m) RNA caps
M Warminski, PJ Sikorski, J Kowalska, J Jemielity
Phosphate Labeling and Sensing in Chemical Biology, 211-239, 2017
492017
Synthesis of Fluorophosphate Nucleotide Analogues and Their Characterization as Tools for 19F NMR Studies
MR Baranowski, A Nowicka, AM Rydzik, M Warminski, R Kasprzyk, ...
The Journal of organic chemistry 80 (8), 3982-3997, 2015
372015
Phosphodiester modifications in mRNA poly (A) tail prevent deadenylation without compromising protein expression
D Strzelecka, M Smietanski, PJ Sikorski, M Warminski, J Kowalska, ...
RNA 26 (12), 1815-1837, 2020
342020
Upregulation of RNA cap methyltransferase RNMT drives ribosome biogenesis during T cell activation
A Galloway, A Kaskar, D Ditsova, A Atrih, H Yoshikawa, C Gomez-Moreira, ...
Nucleic Acids Research 49 (12), 6722-6738, 2021
312021
2′-O-Methylation of the second transcribed nucleotide within the mRNA 5′ cap impacts the protein production level in a cell-specific manner and contributes to …
K Drazkowska, R Tomecki, M Warminski, N Baran, D Cysewski, A Depaix, ...
Nucleic acids research 50 (16), 9051-9071, 2022
292022
mRNA cap analogues substituted in the tetraphosphate chain with CX2: identification of O-to-CCl2 as the first bridging modification that confers resistance to …
AM Rydzik, M Warminski, PJ Sikorski, MR Baranowski, S Walczak, ...
Nucleic Acids Research 45 (15), 8661-8675, 2017
292017
The synthesis of isopropylidene mRNA cap analogs modified with phosphorothioate moiety and their evaluation as promoters of mRNA translation
M Warminski, J Kowalska, J Buck, J Zuberek, M Lukaszewicz, C Nicola, ...
Bioorganic & medicinal chemistry letters 23 (13), 3753-3758, 2013
262013
Azido‐Functionalized 5′ Cap Analogues for the Preparation of Translationally Active mRNAs Suitable for Fluorescent Labeling in Living Cells
A Mamot, PJ Sikorski, M Warminski, J Kowalska, J Jemielity
Angewandte Chemie 129 (49), 15834-15838, 2017
232017
Amino-functionalized 5′ cap analogs as tools for site-specific sequence-independent labeling of mRNA
M Warminski, PJ Sikorski, Z Warminska, M Lukaszewicz, A Kropiwnicka, ...
Bioconjugate Chemistry 28 (7), 1978-1992, 2017
202017
Structural insights into the interaction of clinically relevant phosphorothioate mRNA cap analogs with translation initiation factor 4E reveal stabilization via electrostatic …
M Warminski, J Kowalska, E Nowak, D Kubacka, R Tibble, R Kasprzyk, ...
ACS Chemical Biology 16 (2), 334-343, 2021
182021
5′-fluoro(di)phosphate-labeled oligonucleotides are versatile molecular probes for studying nucleic acid secondary structure and interactions by 19F NMR
MR Baranowski, M Warminski, J Jemielity, J Kowalska
Nucleic Acids Research 48 (15), 8209-8224, 2020
172020
Nicotinamide-containing di-and trinucleotides as chemical tools for studies of NAD-capped RNAs
A Mlynarska-Cieslak, A Depaix, E Grudzien-Nogalska, PJ Sikorski, ...
Organic letters 20 (23), 7650-7655, 2018
172018
Clickable trimethylguanosine cap analogs modified within the triphosphate bridge: synthesis, conjugation to RNA and susceptibility to degradation
BA Wojtczak, M Warminski, J Kowalska, M Lukaszewicz, M Honcharenko, ...
RSC advances 6 (10), 8317-8328, 2016
152016
Kinetic analysis of IFIT1 and IFIT5 interactions with different native and engineered RNAs and its consequences for designing mRNA-based therapeutics
B Miedziak, A Dobieżyńska, ZM Darżynkiewicz, J Bartkowska, ...
RNA 26 (1), 58-68, 2020
142020
Synthesis of RNA 5′-Azides from 2′-O-Pivaloyloxymethyl-Protected RNAs and Their Reactivity in Azide–Alkyne Cycloaddition Reactions
M Warminski, J Kowalska, J Jemielity
Organic letters 19 (13), 3624-3627, 2017
132017
Chemical modifications of mRNA ends for therapeutic applications
M Warminski, A Mamot, A Depaix, J Kowalska, J Jemielity
Accounts of Chemical Research 56 (20), 2814-2826, 2023
92023
Structure of the poxvirus decapping enzyme D9 reveals its mechanism of cap recognition and catalysis
JK Peters, RW Tibble, M Warminski, J Jemielity, JD Gross
Structure 30 (5), 721-732. e4, 2022
82022
Selective Chemical Modification of DNA with Boronic Acids by On-Column CuAAc Reactions
M Debiais, JJ Vasseur, S Müller, M Smietana
Synthesis 52 (20), 2962-2969, 2020
82020
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