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Donald Lorimer
Donald Lorimer
Senior Manager, Structural Biology, Beryllium Discovery
Zweryfikowany adres z be4.com
Tytuł
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In vivo progression of LAPC-9 and LNCaP prostate cancer models to androgen independence is associated with increased expression of insulin-like growth factor I (IGF-I) and IGF …
T Nickerson, F Chang, D Lorimer, SP Smeekens, CL Sawyers, M Pollak
Cancer research 61 (16), 6276-6280, 2001
2942001
Cloning and characterization of a novel human histone deacetylase, HDAC8
JJ Buggy, ML SIDERIS, P MAK, DD LORIMER, B MCINTOSH, JM CLARK
Biochemical Journal 350 (1), 199-205, 2000
2772000
Expression of the catalytic domain of myosin light chain kinase increases paracellular permeability
G Hecht, L Pestic, G Nikcevic, A Koutsouris, J Tripuraneni, DD Lorimer, ...
American Journal of Physiology-Cell Physiology 271 (5), C1678-C1684, 1996
1621996
Structural model of the dimeric Parkinson’s protein LRRK2 reveals a compact architecture involving distant interdomain contacts
G Guaitoli, F Raimondi, BK Gilsbach, Y Gómez-Llorente, E Deyaert, ...
Proceedings of the National Academy of Sciences 113 (30), E4357-E4366, 2016
1562016
Lysyl-tRNA synthetase as a drug target in malaria and cryptosporidiosis
B Baragaña, B Forte, R Choi, S Nakazawa Hewitt, JA Bueren-Calabuig, ...
Proceedings of the National Academy of Sciences 116 (14), 7015-7020, 2019
1032019
Cloning and quantification of galanin-1 receptor expression by mucosal cells lining the human gastrointestinal tract
DD Lorimer, RV Benya
Biochemical and biophysical research communications 222 (2), 379-385, 1996
751996
Challenging the state of the art in protein structure prediction: Highlights of experimental target structures for the 10th Critical Assessment of Techniques for Protein …
A Kryshtafovych, J Moult, P Bales, JF Bazan, M Biasini, A Burgin, C Chen, ...
Proteins: Structure, Function, and Bioinformatics 82, 26-42, 2014
662014
Location and characterization of the human GRP receptor expressed by gastrointestinal epithelial cells
HA Ferris, RE Carroll, DL Lorimer, RV Benya
Peptides 18 (5), 663-672, 1997
661997
Biochemical and Structural Characterization of Selective Allosteric Inhibitors of the Plasmodium falciparum Drug Target, Prolyl-tRNA-synthetase
SN Hewitt, DM Dranow, BG Horst, JA Abendroth, B Forte, I Hallyburton, ...
ACS infectious diseases 3 (1), 34-44, 2017
562017
Cloning, chromosomal location, and transcriptional regulation of the human galanin-1 receptor gene (GALN1R)
DD Lorimer, K Matkowskj, RV Benya
Biochemical and biophysical research communications 241 (2), 558-564, 1997
421997
Fibroblast Contractility without an Increase in Basal Myosin Light Chain Phosphorylation in Wild Type Cells and Cells Expressing the Catalytic Domain of Myosin Light Chain …
K Obara, G Nikcevic, L Pestic, G Nowak, DD Lorimer, V Guerriero, ...
Journal of Biological Chemistry 270 (32), 18734-18737, 1995
371995
Mycofactocin-associated mycobacterial dehydrogenases with non-exchangeable NAD cofactors
DH Haft, PG Pierce, SJ Mayclin, A Sullivan, AS Gardberg, J Abendroth, ...
Scientific reports 7 (1), 41074, 2017
282017
A structural biology approach enables the development of antimicrobials targeting bacterial immunophilins
DW Begley, D Fox III, D Jenner, C Juli, PG Pierce, J Abendroth, M Muruthi, ...
Antimicrobial agents and chemotherapy 58 (3), 1458-1467, 2014
282014
Structure of acid deoxyribonuclease
A Varela-Ramirez, J Abendroth, AA Mejia, IQ Phan, DD Lorimer, ...
Nucleic acids research 45 (10), 6217-6227, 2017
272017
Brucella melitensis Methionyl-tRNA-Synthetase (MetRS), a Potential Drug Target for Brucellosis
KK Ojo, RM Ranade, Z Zhang, DM Dranow, JB Myers, R Choi, ...
PLOS one 11 (8), e0160350, 2016
252016
Expression of a mutant myosin light chain that cannot be phosphorylated increases paracellular permeability
S Gandhi, DD Lorimer, P De Lanerolle
American Journal of Physiology-Renal Physiology 272 (2), F214-F221, 1997
241997
Some of the most interesting CASP 11 targets through the eyes of their authors
A Kryshtafovych, J Moult, A Baslé, A Burgin, TK Craig, RA Edwards, ...
Proteins: Structure, Function, and Bioinformatics 84, 34-50, 2016
202016
Inhibitor-bound complexes of dihydrofolate reductase-thymidylate synthase from Babesia bovis
DW Begley, TE Edwards, AC Raymond, ER Smith, RC Hartley, ...
Acta Crystallographica Section F: Structural Biology and Crystallization …, 2011
202011
Naegleria fowleri: Protein structures to facilitate drug discovery for the deadly, pathogenic free-living amoeba
L Tillery, K Barrett, J Goldstein, JW Lassner, B Osterhout, NL Tran, L Xu, ...
PLoS One 16 (3), e0241738, 2021
172021
Discovery and Characterization of Potent, Efficacious, Orally Available Antimalarial Plasmepsin X Inhibitors and Preclinical Safety Assessment of UCB7362
MA Lowe, A Cardenas, JP Valentin, Z Zhu, J Abendroth, JL Castro, ...
Journal of medicinal chemistry 65 (20), 14121-14143, 2022
152022
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