The conformational wave in capsaicin activation of transient receptor potential vanilloid 1 ion channel F Yang, X Xiao, BH Lee, S Vu, W Yang, V Yarov-Yarovoy, J Zheng Nature communications 9 (1), 2879, 2018 | 67 | 2018 |
A non-covalent ligand reveals biased agonism of the TRPA1 ion channel C Liu, R Reese, S Vu, L Rougé, SD Shields, S Kakiuchi-Kiyota, H Chen, ... Neuron 109 (2), 273-284. e4, 2021 | 61 | 2021 |
Rational design and validation of a vanilloid-sensitive TRPV2 ion channel F Yang, S Vu, V Yarov-Yarovoy, J Zheng Proceedings of the National Academy of Sciences 113 (26), E3657-E3666, 2016 | 54 | 2016 |
Structural mechanisms underlying activation of TRPV1 channels by pungent compounds in gingers Y Yin, Y Dong, S Vu, F Yang, V Yarov‐Yarovoy, Y Tian, J Zheng British journal of pharmacology 176 (17), 3364-3377, 2019 | 50 | 2019 |
A distinct structural mechanism underlies TRPV1 activation by piperine Y Dong, Y Yin, S Vu, F Yang, V Yarov-Yarovoy, Y Tian, J Zheng Biochemical and biophysical research communications 516 (2), 365-372, 2019 | 44 | 2019 |
Gain-of-function mutations in TRPM4 activation gate cause progressive symmetric erythrokeratodermia H Wang, Z Xu, BH Lee, S Vu, L Hu, M Lee, D Bu, X Cao, S Hwang, ... Journal of Investigative Dermatology 139 (5), 1089-1097, 2019 | 41 | 2019 |
Src Regulates Cigarette Smoke–Induced Ceramide Generation via Neutral Sphingomyelinase 2 in the Airway Epithelium S Chung, S Vu, S Filosto, T Goldkorn American journal of respiratory cell and molecular biology 52 (6), 738-748, 2015 | 24 | 2015 |
A specialized pore turret in the mammalian cation channel TRPV1 is responsible for distinct and species-specific heat activation thresholds G Du, Y Tian, Z Yao, S Vu, J Zheng, L Chai, KW Wang, S Yang Journal of Biological Chemistry 295 (28), 9641-9649, 2020 | 21 | 2020 |
A centipede toxin causes rapid desensitization of nociceptor TRPV1 ion channel A Zhu, A Aierken, Z Yao, S Vu, Y Tian, J Zheng, S Yang, F Yang Toxicon 178, 41-49, 2020 | 13 | 2020 |
Exploring functional roles of TRPV1 intracellular domains with unstructured peptide-insertion screening L Ma, F Yang, S Vu, J Zheng Scientific reports 6 (1), 33827, 2016 | 13 | 2016 |
New capsaicin analogs as molecular rulers to define the permissive conformation of the mouse TRPV1 ligand-binding pocket S Vu, V Singh, H Wulff, V Yarov-Yarovoy, J Zheng Elife 9, e62039, 2020 | 11 | 2020 |
Opening of capsaicin receptor TRPV1 is stabilized equally by its four subunits S Li, PT Nguyen, S Vu, V Yarov-Yarovoy, J Zheng Journal of Biological Chemistry 299 (6), 2023 | 4 | 2023 |
Gain-of-function of TRPM4 predisposes mice to psoriasiform dermatitis D Yamada, S Vu, X Wu, Z Shi, D Morris, JD Bloomstein, M Huynh, ... Frontiers in Immunology 13, 1025499, 2022 | 3 | 2022 |