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Gavin Collie
Gavin Collie
AstraZeneca
Verified email at icr.ac.uk - Homepage
Title
Cited by
Cited by
Year
The application of DNA and RNA G-quadruplexes to therapeutic medicines
GW Collie, GN Parkinson
Chemical Society Reviews 40 (12), 5867-5892, 2011
6152011
A crystallographic and modelling study of a human telomeric RNA (TERRA) quadruplex
GW Collie, SM Haider, S Neidle, GN Parkinson
Nucleic acids research 38 (16), 5569-5580, 2010
2672010
Structural basis for telomeric G-quadruplex targeting by naphthalene diimide ligands
GW Collie, R Promontorio, SM Hampel, M Micco, S Neidle, GN Parkinson
Journal of the American Chemical Society 134 (5), 2723-2731, 2012
2462012
Structure-based design and evaluation of naphthalene diimide G-quadruplex ligands as telomere targeting agents in pancreatic cancer cells
M Micco, GW Collie, AG Dale, SA Ohnmacht, I Pazitna, M Gunaratnam, ...
Journal of medicinal chemistry 56 (7), 2959-2974, 2013
1922013
Electrospray mass spectrometry of telomeric RNA (TERRA) reveals the formation of stable multimeric G-quadruplex structures
GW Collie, GN Parkinson, S Neidle, F Rosu, E De Pauw, V Gabelica
Journal of the American Chemical Society 132 (27), 9328-9334, 2010
1522010
Structural basis of telomeric RNA quadruplex− acridine ligand recognition
GW Collie, S Sparapani, GN Parkinson, S Neidle
Journal of the American Chemical Society 133 (8), 2721-2728, 2011
1412011
Shaping quaternary assemblies of water-soluble non-peptide helical foldamers by sequence manipulation
GW Collie, K Pulka-Ziach, CM Lombardo, J Fremaux, F Rosu, ...
Nature Chemistry 7 (11), 871-878, 2015
1322015
Observation of unphosphorylated STAT3 core protein binding to target dsDNA by PEMSA and X-ray crystallography
E Nkansah, R Shah, GW Collie, GN Parkinson, J Palmer, KM Rahman, ...
FEBS letters 587 (7), 833-839, 2013
842013
Selectivity in small molecule binding to human telomeric RNA and DNA quadruplexes
G Collie, AP Reszka, SM Haider, V Gabelica, GN Parkinson, S Neidle
Chemical communications, 7482-7484, 2009
652009
Racemic DNA crystallography
PK Mandal, GW Collie, B Kauffmann, I Huc
Angewandte Chemie 126 (52), 14652-14655, 2014
502014
Achieving In Vivo Target Depletion through the Discovery and Optimization of Benzimidazolone BCL6 Degraders
BR Bellenie, KMJ Cheung, A Varela, OA Pierrat, GW Collie, GM Box, ...
Journal of Medicinal Chemistry 63 (8), 4047-4068, 2020
472020
Loop flexibility in human telomeric quadruplex small-molecule complexes
GW Collie, NH Campbell, S Neidle
Nucleic acids research 43 (10), 4785-4799, 2015
472015
Molecular recognition within the cavity of a foldamer helix bundle: Encapsulation of primary alcohols in aqueous conditions
GW Collie, R Bailly, K Pulka-Ziach, CM Lombardo, L Mauran, ...
Journal of the American Chemical Society 139 (17), 6128-6137, 2017
462017
Crystallography of DNA and RNA G‐Quadruplex Nucleic Acids and Their Ligand Complexes
N Campbell, GW Collie, S Neidle
Current Protocols in Nucleic Acid Chemistry 50 (1), 17.6. 1-17.6. 22, 2012
412012
Anatomy of an oligourea six-helix bundle
CM Lombardo, GW Collie, K Pulka-Ziach, F Rosu, V Gabelica, ...
Journal of the American Chemical Society 138 (33), 10522-10530, 2016
402016
Structural and molecular insight into resistance mechanisms of first generation cMET inhibitors
GW Collie, CM Koh, DJ O’Neill, CJ Stubbs, P Khurana, A Eddershaw, ...
ACS Medicinal Chemistry Letters 10 (9), 1322-1327, 2019
372019
Structural characterization of short hybrid urea/carbamate (U/C) foldamers: A case of partial helix unwinding
YR Nelli, L Fischer, GW Collie, B Kauffmann, G Guichard
Peptide Science 100 (6), 687-697, 2013
292013
A naphthalene diimide G-quadruplex ligand inhibits cell growth and down-regulates BCL-2 expression in an imatinib-resistant gastrointestinal cancer cell line
M Gunaratnam, GW Collie, AP Reszka, AK Todd, GN Parkinson, S Neidle
Bioorganic & Medicinal Chemistry 26 (11), 2958-2964, 2018
262018
X-ray crystallographic studies of G-quadruplex structures
GN Parkinson, GW Collie
G-Quadruplex Nucleic Acids: Methods and Protocols, 131-155, 2019
192019
Structural basis for targeting the folded P-loop conformation of c-MET
GW Collie, IN Michaelides, K Embrey, CJ Stubbs, U Börjesson, IL Dale, ...
ACS Medicinal Chemistry Letters 12 (1), 162-167, 2020
132020
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