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Programmable editing of a target base in genomic DNA without double-stranded DNA cleavage AC Komor, YB Kim, MS Packer, JA Zuris, DR Liu Nature 533 (7603), 420-424, 2016 | 4200 | 2016 |
Programmable base editing of A• T to G• C in genomic DNA without DNA cleavage NM Gaudelli, AC Komor, HA Rees, MS Packer, AH Badran, DI Bryson, ... Nature 551 (7681), 464-471, 2017 | 3083 | 2017 |
Search-and-replace genome editing without double-strand breaks or donor DNA AV Anzalone, PB Randolph, JR Davis, AA Sousa, LW Koblan, JM Levy, ... Nature 576 (7785), 149-157, 2019 | 2858 | 2019 |
Scaling of theory‐of‐mind tasks HM Wellman, D Liu Child development 75 (2), 523-541, 2004 | 2680 | 2004 |
Oncogenic signaling pathways in the cancer genome atlas F Sanchez-Vega, M Mina, J Armenia, WK Chatila, A Luna, KC La, ... Cell 173 (2), 321-337. e10, 2018 | 2152 | 2018 |
DAVID Bioinformatics Resources: expanded annotation database and novel algorithms to better extract biology from large gene lists DW Huang, BT Sherman, Q Tan, J Kir, D Liu, D Bryant, Y Guo, ... Nucleic acids research 35 (suppl_2), W169-W175, 2007 | 2102 | 2007 |
High-throughput profiling of off-target DNA cleavage reveals RNA-programmed Cas9 nuclease specificity V Pattanayak, S Lin, JP Guilinger, E Ma, JA Doudna, DR Liu Nature biotechnology 31 (9), 839-843, 2013 | 1759 | 2013 |
Ipilimumab versus placebo after radiotherapy in patients with metastatic castration-resistant prostate cancer that had progressed after docetaxel chemotherapy (CA184-043): a … ED Kwon, CG Drake, HI Scher, K Fizazi, A Bossi, AJM Van den Eertwegh, ... The lancet oncology 15 (7), 700-712, 2014 | 1467 | 2014 |
Cationic lipid-mediated delivery of proteins enables efficient protein-based genome editing in vitro and in vivo JA Zuris, DB Thompson, Y Shu, JP Guilinger, JL Bessen, JH Hu, ... Nature biotechnology 33 (1), 73-80, 2015 | 1409 | 2015 |
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Genome editing with CRISPR–Cas nucleases, base editors, transposases and prime editors AV Anzalone, LW Koblan, DR Liu Nature biotechnology 38 (7), 824-844, 2020 | 1245 | 2020 |
Base editing: precision chemistry on the genome and transcriptome of living cells HA Rees, DR Liu Nature reviews genetics 19 (12), 770-788, 2018 | 1216 | 2018 |
Sequence-controlled polymers JF Lutz, M Ouchi, DR Liu, M Sawamoto Science 341 (6146), 1238149, 2013 | 1155 | 2013 |
CRISPR-based technologies for the manipulation of eukaryotic genomes AC Komor, AH Badran, DR Liu Cell 168 (1), 20-36, 2017 | 1118 | 2017 |
Fusion of catalytically inactive Cas9 to FokI nuclease improves the specificity of genome modification JP Guilinger, DB Thompson, DR Liu Nature biotechnology 32 (6), 577-582, 2014 | 1113 | 2014 |
A small-molecule inhibitor of Tgf-β signaling replaces Sox2 in reprogramming by inducing Nanog JK Ichida, J Blanchard, K Lam, EY Son, JE Chung, D Egli, KM Loh, ... Cell stem cell 5 (5), 491-503, 2009 | 924 | 2009 |
Methods for the directed evolution of proteins MS Packer, DR Liu Nature Reviews Genetics 16 (7), 379-394, 2015 | 922 | 2015 |
A cancer cell program promotes T cell exclusion and resistance to checkpoint blockade L Jerby-Arnon, P Shah, MS Cuoco, C Rodman, MJ Su, JC Melms, ... Cell 175 (4), 984-997. e24, 2018 | 901 | 2018 |
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