Marcin Poreba
Marcin Poreba
Wroclaw University of Science and Technology
Zweryfikowany adres z pwr.edu.pl - Strona główna
TytułCytowane przezRok
Caspase substrates and inhibitors
M Poręba, A Stróżyk, GS Salvesen, M Drąg
Cold Spring Harbor perspectives in biology 5 (8), a008680, 2013
132*2013
Design of ultrasensitive probes for human neutrophil elastase through hybrid combinatorial substrate library profiling
P Kasperkiewicz, M Poreba, SJ Snipas, H Parker, CC Winterbourn, ...
Proceedings of the National Academy of Sciences 111 (7), 2518-2523, 2014
762014
Probing the S1 specificity pocket of the aminopeptidases that generate antigenic peptides
E Zervoudi, A Papakyriakou, D Georgiadou, I Evnouchidou, A Gajda, ...
Biochemical Journal 435 (2), 411-420, 2011
672011
Mechanism and specificity of the human paracaspase MALT1
J Hachmann, SJ Snipas, BJ van Raam, EM Cancino, EJ Houlihan, ...
Biochemical Journal 443 (1), 287-295, 2012
652012
Fingerprinting the substrate specificity of M1 and M17 aminopeptidases of human malaria, Plasmodium falciparum
M Poreba, S McGowan, TS Skinner-Adams, KR Trenholme, DL Gardiner, ...
PLoS One 7 (2), e31938, 2012
502012
Unnatural amino acids increase sensitivity and provide for the design of highly selective caspase substrates
M Poreba, P Kasperkiewicz, SJ Snipas, D Fasci, GS Salvesen, M Drag
Cell death and differentiation 21 (9), 1482, 2014
462014
Structural and functional insights into caseinolytic proteases reveal an unprecedented regulation principle of their catalytic triad
E Zeiler, A List, F Alte, M Gersch, R Wachtel, M Poreba, M Drag, M Groll, ...
Proceedings of the National Academy of Sciences 110 (28), 11302-11307, 2013
442013
Current strategies for probing substrate specificity of proteases
M Poreba, M Drag
Current medicinal chemistry 17 (33), 3968-3995, 2010
412010
Extended substrate specificity and first potent irreversible inhibitor/activity-based probe design for Zika virus NS2B-NS3 protease
W Rut, L Zhang, P Kasperkiewicz, M Poreba, R Hilgenfeld, M Drąg
Antiviral research 139, 88-94, 2017
322017
Small molecule active site directed tools for studying human caspases
M Poreba, A Szalek, P Kasperkiewicz, W Rut, GS Salvesen, M Drag
Chemical reviews 115 (22), 12546-12629, 2015
312015
Unnatural amino acids increase activity and specificity of synthetic substrates for human and malarial cathepsin C
M Poreba, M Mihelic, P Krai, J Rajkovic, A Krezel, M Pawelczak, ...
Amino acids 46 (4), 931-943, 2014
302014
Counter selection substrate library strategy for developing specific protease substrates and probes
M Poreba, R Solberg, W Rut, NN Lunde, P Kasperkiewicz, SJ Snipas, ...
Cell chemical biology 23 (8), 1023-1035, 2016
272016
Design of a selective substrate and activity based probe for human neutrophil serine protease 4
P Kasperkiewicz, M Poreba, SJ Snipas, SJ Lin, D Kirchhofer, ...
PloS one 10 (7), e0132818, 2015
272015
X-ray crystal structure and specificity of the Plasmodium falciparum malaria aminopeptidase PfM18AAP
KK Sivaraman, CA Oellig, K Huynh, SC Atkinson, M Poreba, MA Perugini, ...
Journal of molecular biology 422 (4), 495-507, 2012
262012
Barrel-shaped ClpP proteases display attenuated cleavage specificities
M Gersch, M Stahl, M Poreba, M Dahmen, A Dziedzic, M Drag, SA Sieber
ACS chemical biology 11 (2), 389-399, 2015
252015
Emerging challenges in the design of selective substrates, inhibitors and activity‐based probes for indistinguishable proteases
P Kasperkiewicz, M Poreba, K Groborz, M Drag
The FEBS journal 284 (10), 1518-1539, 2017
232017
The new esters derivatives of betulin and betulinic acid in epidermoid squamous carcinoma treatment–In vitro studies
M Drąg-Zalesińska, T Wysocka, S Borska, M Drąg, M Poręba, ...
Biomedicine & Pharmacotherapy 72, 91-97, 2015
232015
Selective imaging of cathepsin L in breast cancer by fluorescent activity-based probes
M Poreba, W Rut, M Vizovisek, K Groborz, P Kasperkiewicz, D Finlay, ...
Chemical science 9 (8), 2113-2129, 2018
202018
Positional scanning substrate combinatorial library (PS-SCL) approach to define caspase substrate specificity
M Poręba, A Szalek, P Kasperkiewicz, M Drąg
Caspases, Paracaspases, and Metacaspases, 41-59, 2014
202014
Synthesis of a HyCoSuL peptide substrate library to dissect protease substrate specificity
M Poreba, GS Salvesen, M Drag
nature protocols 12 (10), 2189, 2017
192017
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Prace 1–20