| OXA-48-mediated ceftazidime-avibactam resistance is associated with evolutionary trade-offs C Fröhlich, V Sørum, AM Thomassen, PJ Johnsen, HKS Leiros, ... Msphere 4 (2), 10.1128/msphere. 00024-19, 2019 | 58* | 2019 |
| Synthesis and preclinical evaluation of TPA-based zinc chelators as metallo-β-lactamase inhibitors C Schnaars, G Kildahl-Andersen, A Prandina, R Popal, S Radix, ... ACS Infectious Diseases 4 (9), 1407-1422, 2018 | 38 | 2018 |
| Evolution of β-lactamase mediated cefiderocol resistance C Fröhlich, V Sørum, N Tokuriki, PJ Johnsen, Ø Samuelsen Journal of Antimicrobial Chemotherapy, 2022 | 32 | 2022 |
| Evolution of β-lactamases and enzyme promiscuity C Fröhlich, JZ Chen, S Gholipour, AN Erdogan, N Tokuriki Protein Engineering, Design and Selection 34, gzab013, 2021 | 27 | 2021 |
| ZN148 Is a Modular Synthetic Metallo-β-Lactamase Inhibitor That Reverses Carbapenem Resistance in Gram-Negative Pathogens In Vivo Ø Samuelsen, OAH Åstrand, C Fröhlich, A Heikal, S Skagseth, ... Antimicrobial Agents and Chemotherapy 64 (6), 10.1128/aac. 02415-19, 2020 | 26 | 2020 |
| Cryptic β-lactamase evolution is driven by low β-lactam concentrations C Fröhlich, JA Gama, K Harms, VHA Hirvonen, BA Lund, ... Msphere 6 (2), 10.1128/msphere. 00108-21, 2021 | 14 | 2021 |
| Synthesis and biological evaluation of new dipicolylamine zinc chelators as metallo-β-lactamase inhibitors A Prandina, S Radix, M Le Borgne, LP Jordheim, Z Bousfiha, C Fröhlich, ... Tetrahedron 75 (11), 1525-1540, 2019 | 13 | 2019 |
| Synthesis and biological evaluation of zinc chelating compounds as metallo-β-lactamase inhibitors G Kildahl-Andersen, C Schnaars, A Prandina, S Radix, M Le Borgne, ... Medchemcomm 10 (4), 528-537, 2019 | 13 | 2019 |
| Structural studies of triazole inhibitors with promising inhibitor effects against antibiotic resistance metallo-β-lactamases Z Muhammad, S Skagseth, M Boomgaren, S Akhter, C Fröhlich, A Ismael, ... Bioorganic & Medicinal Chemistry 28 (15), 115598, 2020 | 12 | 2020 |
| Structural and biochemical characterization of the environmental MBLs MYO-1, ECV-1 and SHD-1 C Fröhlich, V Sørum, S Huber, Ø Samuelsen, F Berglund, E Kristiansson, ... Journal of Antimicrobial Chemotherapy 75 (9), 2554-2563, 2020 | 9 | 2020 |
| Kinetics, Thermodynamics, and Structural Effects of Quinoline-2-Carboxylates, Zinc-Binding Inhibitors of New Delhi Metallo-β-lactamase-1 Re-sensitizing Multidrug-Resistant … Y Jia, B Schroeder, Y Pfeifer, C Fröhlich, L Deng, C Arkona, B Kuropka, ... Journal of Medicinal Chemistry 66 (17), 11761-11791, 2023 | 4 | 2023 |
| On the Evolvability of OXA-48 C Fröhlich UiT The Arctic University of Norway, 2021 | 2 | 2021 |
| Epistasis arises from shifting the rate-limiting step during enzyme evolution of a β-lactamase C Fröhlich, HA Bunzel, K Buda, AJ Mulholland, MW Van der Kamp, ... Nature Catalysis, 1-11, 2024 | 1 | 2024 |
| The Biofilm Lifestyle Shapes the Evolution of β-Lactamases ØM Lorentzen, ASB Haukefer, PJ Johnsen, C Frøhlich Genome Biology and Evolution 16 (3), evae030, 2024 | | 2024 |
| Fluorinated captopril analogues inhibit metallo-β-lactamases and facilitate structure determination of NDM-1 binding pose A Kondratieva, K Palica, C Frøhlich, RR Hovd, HKS Leiros, M Erdelyi, ... European Journal of Medicinal Chemistry 266, 116140, 2024 | | 2024 |
Ørjan SamuelsenUniversity Hospital of North Norway/UiT The Arctic University of NorwayVerified email at unn.no
