CRISPR screen in regulatory T cells reveals modulators of Foxp3 JT Cortez, E Montauti, E Shifrut, J Gatchalian, Y Zhang, O Shaked, Y Xu, ... Nature 582 (7812), 416-420, 2020 | 162 | 2020 |
The transcriptional regulator Aire coopts the repressive ATF7ip-MBD1 complex for the induction of immunotolerance M Waterfield, IS Khan, JT Cortez, U Fan, T Metzger, A Greer, K Fasano, ... Nature immunology 15 (3), 258-265, 2014 | 107 | 2014 |
Functional CRISPR dissection of gene networks controlling human regulatory T cell identity K Schumann, SS Raju, M Lauber, S Kolb, E Shifrut, JT Cortez, N Skartsis, ... Nature immunology 21 (11), 1456-1466, 2020 | 63 | 2020 |
Systematic discovery and perturbation of regulatory genes in human T cells reveals the architecture of immune networks JW Freimer, O Shaked, S Naqvi, N Sinnott-Armstrong, A Kathiria, ... Nature genetics 54 (8), 1133-1144, 2022 | 50 | 2022 |
Elastase 3B mutation links to familial pancreatitis with diabetes and pancreatic adenocarcinoma PC Moore, JT Cortez, CE Chamberlain, D Alba, AC Berger, Z Quandt, ... The Journal of clinical investigation 129 (11), 4676-4681, 2019 | 30 | 2019 |
A large CRISPR-induced bystander mutation causes immune dysregulation DR Simeonov, AJ Brandt, AY Chan, JT Cortez, Z Li, JM Woo, Y Lee, ... Communications biology 2 (1), 70, 2019 | 23 | 2019 |
The epigenetic regulator ATF7ip inhibits Il2 expression, regulating Th17 responses JH Sin, C Zuckerman, JT Cortez, WL Eckalbar, DJ Erle, MS Anderson, ... Journal of Experimental Medicine 216 (9), 2024-2037, 2019 | 16 | 2019 |
T cell subset-selective IL2RA enhancers shape autoimmune diabetes risk DR Simeonov, HS Wong, JT Cortez, A Young, Z Li, V Nguyen, K Park, ... BioRxiv, 2020.07. 22.216564, 2020 | 8 | 2020 |
ATF7ip targets transposable elements for H3K9me3 deposition to modify CD8+ T cell effector and memory responses JH Sin, S Kashyap, D Acenas, JT Cortez, J Lee, A Marson, M Matloubian, ... The Journal of Immunology 208 (5), 1155-1169, 2022 | 3 | 2022 |
Non-coding sequence variation reveals fragility within interleukin 2 feedback circuitry and shapes autoimmune disease risk DR Simeonov, K Park, JT Cortez, A Young, Z Li, V Nguyen, J Umhoefer, ... bioRxiv, 2023 | 1 | 2023 |
USP22 stabilizes FoxP3 to maintain Regulatory T cell function through a dual mechanism resulting in tumor immune evasion E Montauti, Y Zhang, J Cortez, A Marson, D Fang The Journal of Immunology 204 (1_Supplement), 244.1-244.1, 2020 | 1 | 2020 |
CRISPR Screen in Regulatory T Cells Reveals Ubiquitination Modulators of Foxp3 JT Cortez, E Montauti, E Shifrut, Y Zhang, O Shaked, Y Xu, TL Roth, ... bioRxiv, 2020.02. 26.966911, 2020 | 1 | 2020 |
Chimeric cytokine receptor provides IL-2 signaling for engineered regulatory T cell therapy JT Cortez, H Ly, E Trotta, JF Matthaei, P Kegler, B Phong, BM Fiebiger, ... The Journal of Immunology 210 (1_Supplement), 166.10-166.10, 2023 | | 2023 |
CD4 JH Sin, S Kashyap, D Acenas, JT Cortez, J Lee, A Marson, M Matloubian, ... Immunology 208, 1è15, 2022 | | 2022 |
Compositions and methods for modifying regulatory t cells A Marson, JT Cortez, JA Bluestone, E Shifrut, F Van Gool US Patent App. 17/284,396, 2021 | | 2021 |
Dissecting the genetic networks that control regulatory T cell stability using pooled CRISPR screens JT Cortez, E Shifrut, Y Lee, MR Mumbach, AT Satpathy, J Granja, ... The Journal of Immunology 200 (1_Supplement), 101.5-101.5, 2018 | | 2018 |
007 GILT-mediated antigen processing in thymic epithelial cells diminishes T cell-mediated protection from melanoma through promoting thymic deletion and regulatory T cells MP Rausch, TC Metzger, M Waterfield, J Cortez, MS Anderson, ... Journal of Investigative Dermatology 136 (5), S2, 2016 | | 2016 |
GILT-mediated processing of a self and melanoma antigen in thymic epithelial cells promotes deletion and regulatory T cells M Rausch, T Metzger, M Waterfield, J Cortez, M Anderson, K Hastings JOURNAL OF IMMUNOLOGY 194, 2015 | | 2015 |
GILT-mediated processing of a self and melanoma antigen in thymic epithelial cells promotes deletion and regulatory T cells (APP3P. 113) M Rausch, T Metzger, M Waterfield, J Cortez, M Anderson, K Hastings The Journal of Immunology 194 (1_Supplement), 113.14-113.14, 2015 | | 2015 |
TCTP as a Regulator of Rheb: Impact on mTOR Signaling M Grabiak, J Cortez, N Parmar The FASEB Journal 26, 761.21-761.21, 2012 | | 2012 |