| Antisense oligonucleotides as therapeutic agents—is the bullet really magical? CA Stein, YC Cheng Science 261 (5124), 1004-1012, 1993 | 1814 | 1993 |
| Antisense oligonucleotides: basic concepts and mechanisms N Dias, CA Stein Molecular cancer therapeutics 1 (5), 347-355, 2002 | 1168 | 2002 |
| Characterization of oligonucleotide transport into living cells. SL Loke, CA Stein, XH Zhang, K Mori, M Nakanishi, C Subasinghe, ... Proceedings of the National Academy of Sciences 86 (10), 3474-3478, 1989 | 1018 | 1989 |
| Inhibitors for replication of retroviruses and for the expression of oncogene products JS Cohen, L Neckers, C Stein, SL Loke, K Shinozuka US Patent 5,264,423, 1993 | 835 | 1993 |
| Inhibitors for replication of retroviruses and for the expression of oncogene products JS Cohen, L Neckers, C Stein, SL Loke, K Shinozuka US Patent 5,276,019, 1994 | 813 | 1994 |
| Physicochemical properties of phospborothioate oligodeoxynucleotides CA Stein, C Subasinghe, K Shinozuka, JS Cohen Nucleic acids research 16 (8), 3209-3221, 1988 | 790 | 1988 |
| Oligodeoxynucleotides as inhibitors of gene expression: a review CA Stein, JS Cohen Cancer Research 48 (10), 2659-2668, 1988 | 784 | 1988 |
| Inhibitors for replication of retroviruses and for the expression of oncogene products JS Cohen, L Neckers, C Stein, SL Loke, K Shinozuka US Patent 5,286,717, 1994 | 749 | 1994 |
| FDA-approved oligonucleotide therapies in 2017 CA Stein, D Castanotto Molecular Therapy 25 (5), 1069-1075, 2017 | 672 | 2017 |
| Establishment and characterization of a human adrenocortical carcinoma cell line that expresses multiple pathways of steroid biosynthesis AF Gazdar, HK Oie, CH Shackleton, TR Chen, TJ Triche, CE Myers, ... Cancer research 50 (17), 5488-5496, 1990 | 551 | 1990 |
| Suramin: an anticancer drug with a unique mechanism of action. CA Stein, RV LaRocca, R Thomas, N McAtee, CE Myers Journal of Clinical Oncology 7 (4), 499-508, 1989 | 435 | 1989 |
| Phosphorothioate oligodeoxynucleotides bind to basic fibroblast growth factor, inhibit its binding to cell surface receptors, and remove it from low affinity binding sites on … MA Guvakova, LA Yakubov, I Vlodavsky, JL Tonkinson, CA Stein Journal of Biological Chemistry 270 (6), 2620-2627, 1995 | 425 | 1995 |
| Antisense-mediated Inhibition of BCL2 Protooncogene Expression and Leukemic Cell Growth and Survival: Comparisons of Phosphodiester and Phosphorothioate … JC Reed, C Stein, C Subasinghe, S Haldar, CM Croce, S Yum, J Cohen Cancer research 50 (20), 6565-6570, 1990 | 417 | 1990 |
| Efficient gene silencing by delivery of locked nucleic acid antisense oligonucleotides, unassisted by transfection reagents CA Stein, JB Hansen, J Lai, SJ Wu, A Voskresenskiy, A H⊘ g, J Worm, ... Nucleic acids research 38 (1), e3-e3, 2010 | 405 | 2010 |
| Differentiation of immortal cells inhibits telomerase activity. HW Sharma, JA Sokoloski, JR Perez, JY Maltese, AC Sartorelli, CA Stein, ... Proceedings of the National Academy of Sciences 92 (26), 12343-12346, 1995 | 398 | 1995 |
| Prostate cancer, version 2.2014 JL Mohler, PW Kantoff, AJ Armstrong, RR Bahnson, M Cohen, ... Journal of the National Comprehensive Cancer Network 12 (5), 686-718, 2014 | 391 | 2014 |
| Regulation of viral expression of human immunodeficiency virus in vitro by an antisense phosphorothioate oligodeoxynucleotide against rev (art/trs) in chronically infected cells. M Matsukura, G Zon, K Shinozuka, M Robert-Guroff, T Shimada, CA Stein, ... Proceedings of the National Academy of Sciences 86 (11), 4244-4248, 1989 | 357 | 1989 |
| Antisense oligonucleotides: promise and reality I Lebedeva, CA Stein Annual review of pharmacology and toxicology 41 (1), 403-419, 2001 | 345 | 2001 |
| Does antisense exist? CA Stein Nature medicine 1 (11), 1119-1121, 1995 | 321 | 1995 |
| Mac-1 (CD11b/CD18) is an oligodeoxynucleotide-binding protein L Benimetskaya, JD Loike, Z Khaled, G LoiKe, SC Silverstein, L Cao, ... Nature medicine 3 (4), 414-420, 1997 | 318 | 1997 |
