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RAMESH KUMAR
RAMESH KUMAR
Research Scientist and CDF Principle Investigator
Verified email at imcb.a-star.edu.sg
Title
Cited by
Cited by
Year
RNF4 is required for DNA double-strand break repair in vivo
R Vyas, R Kumar, F Clermont, A Helfricht, P Kalev, P Sotiropoulou, ...
Cell Death & Differentiation 20 (3), 490-502, 2013
1242013
The STUbL RNF4 regulates protein group SUMOylation by targeting the SUMO conjugation machinery
R Kumar, R González-Prieto, Z Xiao, M Verlaan-de Vries, ACO Vertegaal
Nature communications 8 (1), 1809, 2017
1102017
c-Myc is targeted to the proteasome for degradation in a SUMOylation-dependent manner, regulated by PIAS1, SENP7 and RNF4
R González-Prieto, SAG Cuijpers, R Kumar, IA Hendriks, ACO Vertegaal
Cell cycle 14 (12), 1859-1872, 2015
1022015
p53 maintains genomic stability by preventing interference between transcription and replication
CQX Yeo, I Alexander, Z Lin, S Lim, OA Aning, R Kumar, ...
Cell reports 15 (1), 132-146, 2016
942016
Dynamics of Rad9 chromatin binding and checkpoint function are mediated by its dimerization and are cell cycle–regulated by CDK1 activity
M Granata, F Lazzaro, D Novarina, D Panigada, F Puddu, CM Abreu, ...
PLoS genetics 6 (8), e1001047, 2010
852010
Mitochondrial uncoupling reveals a novel therapeutic opportunity for p53-defective cancers
R Kumar, L Coronel, B Somalanka, A Raju, OA Aning, O An, YS Ho, ...
Nature communications 9 (1), 3931, 2018
742018
RIF1: a novel regulatory factor for DNA replication and DNA damage response signaling
R Kumar, CF Cheok
DNA repair 15, 54-59, 2014
722014
Site-specific phosphorylation of the DNA damage response mediator rad9 by cyclin-dependent kinases regulates activation of checkpoint kinase 1
CM Abreu, R Kumar, D Hamilton, AW Dawdy, K Creavin, S Eivers, K Finn, ...
PLoS genetics 9 (4), e1003310, 2013
452013
Therapeutic targeting of TEAD transcription factors in cancer
AV Pobbati, R Kumar, BP Rubin, W Hong
Trends in Biochemical Sciences, 2023
402023
RNF4—a paradigm for SUMOylation‐mediated ubiquitination
R Kumar, K Sabapathy
Proteomics 19 (21-22), 1900185, 2019
302019
Dynamics of RIF1 SUMOylation is regulated by PIAS4 in the maintenance of Genomic Stability
R Kumar, CF Cheok
Scientific Reports 7 (1), 17367, 2017
192017
Abstract LB033: Identification of small molecule Pan-TEAD inhibitors disrupting YAP-TEAD protein-protein interaction and targeting gastric cancer cells
R Kumar, J Toh, J Thian, NF Mohideen, J Sun, S Chakraborty, ...
Cancer Research 84 (7_Supplement), LB033-LB033, 2024
2024
Hippo Signaling at the Hallmarks of Cancer and Drug Resistance
R KUMAR, W Hong
Cells, 2024
2024
RNF4-A Paradigm for SUMOylation-Mediated Ubiquitination (vol 19, 1900185, 2019)
R Kumar, K Sabapathy
PROTEOMICS 21 (5), 2021
2021
Use of niclosamide in the treatment of p53-deficient cells
R KUMAR
SG Patent WO2,017,048,197, 2016
2016
Role of Rad9 cell cycle phosphorylation in the regulation of Chk1 activation
R Kumar
National University of Ireland, Galway, 2012
2012
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