| Microglia constitute a barrier that prevents neurotoxic protofibrillar Aβ42 hotspots around plaques C Condello, P Yuan, A Schain, J Grutzendler Nature communications 6 (1), 6176, 2015 | 542 | 2015 |
| CX3CR1 in microglia regulates brain amyloid deposition through selective protofibrillar amyloid-β phagocytosis Z Liu, C Condello, A Schain, R Harb, J Grutzendler Journal of Neuroscience 30 (50), 17091-17101, 2010 | 298 | 2010 |
| Cortical spreading depression closes paravascular space and impairs glymphatic flow: implications for migraine headache AJ Schain, A Melo-Carrillo, AM Strassman, R Burstein Journal of Neuroscience 37 (11), 2904-2915, 2017 | 206 | 2017 |
| Label-free in vivo imaging of myelinated axons in health and disease with spectral confocal reflectance microscopy AJ Schain, RA Hill, J Grutzendler Nature medicine 20 (4), 443-449, 2014 | 181 | 2014 |
| Fremanezumab—a humanized monoclonal anti-CGRP antibody—inhibits thinly myelinated (Aδ) but not unmyelinated (C) meningeal nociceptors A Melo-Carrillo, AM Strassman, RR Nir, AJ Schain, R Noseda, J Stratton, ... Journal of Neuroscience 37 (44), 10587-10596, 2017 | 179 | 2017 |
| Selective inhibition of trigeminovascular neurons by fremanezumab: a humanized monoclonal anti-CGRP antibody A Melo-Carrillo, R Noseda, RR Nir, AJ Schain, J Stratton, AM Strassman, ... Journal of Neuroscience 37 (30), 7149-7163, 2017 | 130 | 2017 |
| Simvastatin and vitamin D for migraine prevention: a randomized, controlled trial C Buettner, RR Nir, SM Bertisch, C Bernstein, A Schain, MA Mittleman, ... Annals of neurology 78 (6), 970-981, 2015 | 123 | 2015 |
| Multicolor time-stamp reveals the dynamics and toxicity of amyloid deposition C Condello, A Schain, J Grutzendler Scientific reports 1 (1), 19, 2011 | 96 | 2011 |
| Upregulation of inflammatory gene transcripts in periosteum of chronic migraineurs: Implications for extracranial origin of headache CJ Perry, P Blake, C Buettner, E Papavassiliou, AJ Schain, MK Bhasin, ... Annals of neurology 79 (6), 1000-1013, 2016 | 76 | 2016 |
| Fluorescently-labeled fremanezumab is distributed to sensory and autonomic ganglia and the dura but not to the brain of rats with uncompromised blood brain barrier R Noseda, AJ Schain, A Melo-Carrillo, J Tien, J Stratton, F Mai, ... Cephalalgia 40 (3), 229-240, 2020 | 74 | 2020 |
| Activation of pial and dural macrophages and dendritic cells by cortical spreading depression AJ Schain, A Melo‐Carrillo, D Borsook, J Grutzendler, AM Strassman, ... Annals of neurology 83 (3), 508-521, 2018 | 69 | 2018 |
| Extracranial origin of headache R Burstein, P Blake, A Schain, C Perry Current opinion in neurology 30 (3), 263-271, 2017 | 64 | 2017 |
| CSD-induced arterial dilatation and plasma protein extravasation are unaffected by fremanezumab: implications for CGRP's role in migraine with aura AJ Schain, A Melo-Carrillo, J Stratton, AM Strassman, R Burstein Journal of Neuroscience 39 (30), 6001-6011, 2019 | 56 | 2019 |
| Exploring the effects of extracranial injections of botulinum toxin type A on prolonged intracranial meningeal nociceptors responses to cortical spreading depression in female rats A Melo-Carrillo, AM Strassman, AJ Schain, R Noseda, S Ashina, A Adams, ... Cephalalgia 39 (11), 1358-1365, 2019 | 32 | 2019 |
| Fremanezumab and its isotype slow propagation rate and shorten cortical recovery period but do not prevent occurrence of cortical spreading depression in rats with compromised … A Melo-Carrillo, AJ Schain, J Stratton, AM Strassman, R Burstein Pain 161 (5), 1037-1043, 2020 | 31 | 2020 |
| Combined onabotulinumtoxinA/atogepant treatment blocks activation/sensitization of high-threshold and wide-dynamic range neurons A Melo-Carrillo, AM Strassman, AJ Schain, AM Adams, MF Brin, ... Cephalalgia 41 (1), 17-32, 2021 | 22 | 2021 |
| Microglia constitute a barrier that prevents neurotoxic protofibrillar Abeta42 hotspots around plaques. Nat Commun. 2015; 6: 6176 C Condello, P Yuan, A Schain, J Grutzendler | 12 | |
| Celecoxib reduces cortical spreading depression–induced macrophage activation and dilatation of dural but not pial arteries in rodents: implications for mechanism of action in … AJ Schain, A Melo-Carrillo, S Ashina, AM Strassman, R Burstein Pain 161 (5), 1019-1026, 2020 | 10 | 2020 |
| Activation of peripheral and central trigeminovascular neurons by seizure: implications for ictal and postictal headache A Melo-Carrillo, AJ Schain, AM Strassman, R Burstein Journal of Neuroscience 40 (27), 5314-5326, 2020 | 8 | 2020 |
| OnabotulinumtoxinA affects cortical recovery period but not occurrence or propagation of cortical spreading depression in rats with compromised blood–brain barrier A Melo-Carrillo, AM Strassman, AJ Schain, RS Broide, BB Cai, ... Pain 162 (9), 2418-2427, 2021 | 3 | 2021 |
Jaime GrutzendlerProfessor of Neurology and Neuroscience, Yale UniversityZweryfikowany adres z yale.edu
