| MYC/PGC-1α balance determines the metabolic phenotype and plasticity of pancreatic cancer stem cells P Sancho, E Burgos-Ramos, A Tavera, TB Kheir, P Jagust, M Schoenhals, ... Cell metabolism 22 (4), 590-605, 2015 | 687 | 2015 |
| Hallmarks of cancer stem cell metabolism P Sancho, D Barneda, C Heeschen British journal of cancer 114 (12), 1305-1312, 2016 | 498 | 2016 |
| Upregulation of the NADPH oxidase NOX4 by TGF-beta in hepatocytes is required for its pro-apoptotic activity I Carmona-Cuenca, C Roncero, P Sancho, L Caja, N Fausto, ... Journal of hepatology 49 (6), 965-976, 2008 | 259 | 2008 |
| TGF-beta signaling in cancer treatment I Fabregat, J Fernando, J Mainez, P Sancho Current pharmaceutical design 20 (17), 2934-2947, 2014 | 218 | 2014 |
| Effect of glutathione depletion on antitumor drug toxicity (apoptosis and necrosis) in U-937 human promonocytic cells: the role of intracellular oxidation A Troyano, C Fernández, P Sancho, E de Blas, P Aller Journal of Biological Chemistry 276 (50), 47107-47115, 2001 | 210 | 2001 |
| Snail1 suppresses TGF-β-induced apoptosis and is sufficient to trigger EMT in hepatocytes DL Franco, J Mainez, S Vega, P Sancho, MM Murillo, CA de Frutos, ... Journal of cell science 123 (20), 3467-3477, 2010 | 184 | 2010 |
| Metformin targets the metabolic achilles heel of human pancreatic cancer stem cells E Lonardo, M Cioffi, P Sancho, Y Sanchez-Ripoll, SM Trabulo, J Dorado, ... PloS one 8 (10), e76518, 2013 | 179 | 2013 |
| NADPH oxidase NOX4 mediates stellate cell activation and hepatocyte cell death during liver fibrosis development P Sancho, J Mainez, E Crosas-Molist, C Roncero, ... Public Library of Science 7 (9), e45285, 2012 | 175 | 2012 |
| Cysteine protease inhibition prevents mitochondrial apoptosis-inducing factor (AIF) release VJ Yuste, RS Moubarak, C Delettre, M Bras, P Sancho, N Robert, ... Cell Death & Differentiation 12 (11), 1445-1448, 2005 | 169 | 2005 |
| The selection between apoptosis and necrosis is differentially regulated in hydrogen peroxide-treated and glutathione-depleted human promonocytic cells A Troyano, P Sancho, C Fernández, E De Blas, P Bernardi, P Aller Cell Death & Differentiation 10 (8), 889-898, 2003 | 143 | 2003 |
| Microenvironmental hCAP-18/LL-37 promotes pancreatic ductal adenocarcinoma by activating its cancer stem cell compartment B Sainz, S Alcala, E Garcia, Y Sanchez-Ripoll, MM Azevedo, M Cioffi, ... Gut 64 (12), 1921-1935, 2015 | 141 | 2015 |
| A mesenchymal‐like phenotype and expression of CD44 predict lack of apoptotic response to sorafenib in liver tumor cells J Fernando, A Malfettone, EB Cepeda, R Vilarrasa‐Blasi, E Bertran, ... International journal of cancer 136 (4), E161-E172, 2015 | 140 | 2015 |
| Overactivation of the MEK/ERK pathway in liver tumor cells confers resistance to TGF-β–induced cell death through impairing up-regulation of the NADPH oxidase NOX4 L Caja, P Sancho, E Bertran, D Iglesias-Serret, J Gil, I Fabregat Cancer research 69 (19), 7595-7602, 2009 | 140 | 2009 |
| Overactivation of the TGF‐β pathway confers a mesenchymal‐like phenotype and CXCR4‐dependent migratory properties to liver tumor cells E Bertran, E Crosas‐Molist, P Sancho, L Caja, J Lopez‐Luque, E Navarro, ... Hepatology 58 (6), 2032-2044, 2013 | 136 | 2013 |
| Metabolism-based therapeutic strategies targeting cancer stem cells P Jagust, B de Luxán-Delgado, B Parejo-Alonso, P Sancho Frontiers in pharmacology 10, 443586, 2019 | 121 | 2019 |
| Pharmacologic inhibitors of PI3K/Akt potentiate the apoptotic action of the antileukemic drug arsenic trioxide via glutathione depletion and increased peroxide accumulation in … AM Ramos, C Fernández, D Amrán, P Sancho, E de Blas, P Aller Blood 105 (10), 4013-4020, 2005 | 119 | 2005 |
| Drp1 mediates caspase-independent type III cell death in normal and leukemic cells M Bras, VJ Yuste, G Roué, S Barbier, P Sancho, C Virely, M Rubio, ... Molecular and cellular biology 27 (20), 7073-7088, 2007 | 117 | 2007 |
| Nicotine promotes initiation and progression of KRAS-induced pancreatic cancer via Gata6-dependent dedifferentiation of acinar cells in mice PC Hermann, P Sancho, M Cañamero, P Martinelli, F Madriles, P Michl, ... Gastroenterology 147 (5), 1119-1133. e4, 2014 | 115 | 2014 |
| Cancer associated fibroblast FAK regulates malignant cell metabolism F Demircioglu, J Wang, J Candido, ASH Costa, P Casado, ... Nature communications 11 (1), 1290, 2020 | 109 | 2020 |
| The NADPH oxidase NOX4 inhibits hepatocyte proliferation and liver cancer progression E Crosas-Molist, E Bertran, P Sancho, J López-Luque, J Fernando, ... Free Radical Biology and Medicine 69, 338-347, 2014 | 98 | 2014 |
