Obserwuj
Amy Hao Li
Amy Hao Li
Principal Scientist, Genentech Inc.
Brak zweryfikowanego adresu e-mail - Strona główna
Tytuł
Cytowane przez
Cytowane przez
Rok
Structure- and function-based design of Plasmodium-selective proteasome inhibitors
H Li, AJ O’Donoghue, WA Van Der Linden, SC Xie, E Yoo, IT Foe, L Tilley, ...
Nature 530 (7589), 233-236, 2016
2422016
Directed Evolution of Ionizing Radiation Resistance in Escherichia coli
DR Harris, SV Pollock, EA Wood, RJ Goiffon, AJ Klingele, EL Cabot, ...
Journal of bacteriology 191 (16), 5240-5252, 2009
1582009
Skin commensal Malassezia globosa secreted protease attenuates Staphylococcus aureus biofilm formation
H Li, BN Goh, WK Teh, Z Jiang, JPZ Goh, A Goh, G Wu, SS Hoon, ...
Journal of Investigative Dermatology 138 (5), 1137-1145, 2018
1172018
Non-invasive imaging of idiopathic pulmonary fibrosis using cathepsin protease probes
NP Withana, X Ma, HM McGuire, M Verdoes, WA van der Linden, LO Ofori, ...
Scientific reports 6 (1), 19755, 2016
992016
Validation of the proteasome as a therapeutic target in Plasmodium using an epoxyketone inhibitor with parasite-specific toxicity
H Li, EL Ponder, M Verdoes, KH Asbjornsdottir, E Deu, LE Edgington, ...
Chemistry & biology 19 (12), 1535-1545, 2012
942012
Proteases as regulators of pathogenesis: examples from the Apicomplexa
H Li, MA Child, M Bogyo
Biochimica et Biophysica Acta (BBA)-Proteins and Proteomics 1824 (1), 177-185, 2012
802012
Design of a highly selective quenched activity-based probe and its application in dual color imaging studies of cathepsin S activity localization
K Oresic Bender, L Ofori, WA van der Linden, ED Mock, GK Datta, ...
Journal of the American Chemical Society 137 (14), 4771-4777, 2015
732015
A wireless and battery-free wound infection sensor based on DNA hydrogel
Z Xiong, S Achavananthadith, S Lian, LE Madden, ZX Ong, W Chua, ...
Science advances 7 (47), eabj1617, 2021
722021
Assessing Subunit Dependency of the Plasmodium Proteasome Using Small Molecule Inhibitors and Active Site Probes
H Li, WA Van Der Linden, M Verdoes, BI Florea, FE McAllister, ...
ACS chemical biology 9 (8), 1869-1876, 2014
542014
Identification of Potent and Selective Non-covalent Inhibitors of the Plasmodium falciparum Proteasome
H Li, C Tsu, C Blackburn, G Li, P Hales, L Dick, M Bogyo
Journal of the American Chemical Society 136 (39), 13562-13565, 2014
532014
The cryo‐EM structure of the Plasmodium falciparum 20S proteasome and its use in the fight against malaria
H Li, M Bogyo, PCA da Fonseca
The FEBS journal 283 (23), 4238-4243, 2016
342016
Templated chemistry for sequence‐specific fluorogenic detection of duplex DNA
H Li, RM Franzini, C Bruner, ET Kool
ChemBioChem 11 (15), 2132-2137, 2010
292010
Identification of Malassezia furfur Secreted Aspartyl Protease 1 (MfSAP1) and Its Role in Extracellular Matrix Degradation
SE Poh, JPZ Goh, C Fan, W Chua, SQ Gan, PLK Lim, B Sharma, ...
Frontiers in cellular and infection microbiology 10, 148, 2020
272020
Defective dissociation of a “slow” RecA mutant protein imparts an Escherichia coli growth defect
JM Cox, H Li, EA Wood, S Chitteni-Pattu, RB Inman, MM Cox
Journal of Biological Chemistry 283 (36), 24909-24921, 2008
262008
Ferrous iron-dependent drug delivery enables controlled and selective release of therapeutic agents in vivo
E Deu, IT Chen, EMW Lauterwasser, J Valderramos, H Li, LE Edgington, ...
Proceedings of the National Academy of Sciences 110 (45), 18244-18249, 2013
252013
Total Synthesis and Biological Evaluation of the Fab‐Inhibitory Antibiotic Platencin and Analogues Thereof
GYC Leung, H Li, QY Toh, AMY Ng, RJ Sum, JE Bandow, DYK Chen
European Journal of Organic Chemistry 2011 (1), 183-196, 2011
242011
Trioxolane-mediated delivery of mefloquine limits brain exposure in a mouse model of malaria
EMW Lauterwasser, SD Fontaine, H Li, J Gut, K Katneni, SA Charman, ...
ACS medicinal chemistry letters 6 (11), 1145-1149, 2015
172015
The human pathobiont Malassezia furfur secreted protease Mfsap1 regulates cell dispersal and exacerbates skin inflammation
JPZ Goh, F Ruchti, SE Poh, WLC Koh, KY Tan, YT Lim, STG Thng, ...
Proceedings of the National Academy of Sciences 119 (49), e2212533119, 2022
122022
Secretory proteases of the human skin microbiome
W Chua, SE Poh, H Li
Infection and Immunity 90 (1), e00397-21, 2022
122022
Expression of Staphylococcus aureus virulence factors in atopic dermatitis
SE Poh, WLC Koh, SYD Lim, ECE Wang, YW Yew, JEA Common, ...
JID Innovations 2 (4), 100130, 2022
82022
Nie można teraz wykonać tej operacji. Spróbuj ponownie później.
Prace 1–20