| BiP‐mediated closing of the Sec61 channel limits Ca2+ leakage from the ER N Schäuble, S Lang, M Jung, S Cappel, S Schorr, Ö Ulucan, J Linxweiler, ... The EMBO journal 31 (15), 3282-3296, 2012 | 194 | 2012 |
| Different effects of Sec61α, Sec62 and Sec63 depletion on transport of polypeptides into the endoplasmic reticulum of mammalian cells S Lang, J Benedix, SV Fedeles, S Schorr, C Schirra, N Schäuble, C Jalal, ... Journal of cell science 125 (8), 1958-1969, 2012 | 193 | 2012 |
| Structure of the mammalian oligosaccharyl-transferase complex in the native ER protein translocon S Pfeffer, J Dudek, M Gogala, S Schorr, J Linxweiler, S Lang, T Becker, ... Nature communications 5 (1), 3072, 2014 | 172 | 2014 |
| An update on Sec61 channel functions, mechanisms, and related diseases S Lang, S Pfeffer, PH Lee, A Cavalié, V Helms, F Förster, R Zimmermann Frontiers in physiology 8, 887, 2017 | 153 | 2017 |
| Interaction of calmodulin with Sec61α limits Ca2+ leakage from the endoplasmic reticulum F Erdmann, N Schäuble, S Lang, M Jung, A Honigmann, M Ahmad, ... The EMBO journal 30 (1), 17-31, 2011 | 129 | 2011 |
| Sec61 complexes form ubiquitous ER Ca2+ leak channels S Lang, F Erdmann, M Jung, R Wagner, A Cavalie, R Zimmermann Channels 5 (3), 228-235, 2011 | 108 | 2011 |
| Structure and 3D arrangement of endoplasmic reticulum membrane-associated ribosomes S Pfeffer, F Brandt, T Hrabe, S Lang, M Eibauer, R Zimmermann, F Förster Structure 20 (9), 1508-1518, 2012 | 102 | 2012 |
| A Drosophila model identifies a critical role for zinc in mineralization for kidney stone disease T Chi, MS Kim, S Lang, N Bose, A Kahn, L Flechner, SD Blaschko, T Zee, ... PloS one 10 (5), e0124150, 2015 | 83 | 2015 |
| TRC40 can deliver short secretory proteins to the Sec61 translocon N Johnson, F Vilardi, S Lang, P Leznicki, R Zimmermann, S High Journal of cell science 125 (15), 3612-3620, 2012 | 82 | 2012 |
| Proteomics reveals signal peptide features determining the client specificity in human TRAP-dependent ER protein import D Nguyen, R Stutz, S Schorr, S Lang, S Pfeffer, HH Freeze, F Förster, ... Nature communications 9 (1), 3765, 2018 | 75 | 2018 |
| hS nd2 protein represents an alternative targeting factor to the endoplasmic reticulum in human cells S Haßdenteufel, M Sicking, S Schorr, N Aviram, C Fecher‐Trost, ... FEBS letters 591 (20), 3211-3224, 2017 | 71 | 2017 |
| AXER is an ATP/ADP exchanger in the membrane of the endoplasmic reticulum MC Klein, K Zimmermann, S Schorr, M Landini, PAW Klemens, J Altensell, ... Nature communications 9 (1), 3489, 2018 | 62 | 2018 |
| Sec62 protein level is crucial for the ER stress tolerance of prostate cancer M Greiner, B Kreutzer, S Lang, V Jung, A Cavalié, G Unteregger, ... The Prostate 71 (10), 1074-1083, 2011 | 52 | 2011 |
| A conserved role of the insulin-like signaling pathway in diet-dependent uric acid pathologies in Drosophila melanogaster S Lang, TA Hilsabeck, KA Wilson, A Sharma, N Bose, DJ Brackman, ... PLoS genetics 15 (8), e1008318, 2019 | 47 | 2019 |
| Structural features within the nascent chain regulate alternative targeting of secretory proteins to mitochondria NV Pfeiffer, D Dirndorfer, S Lang, UK Resenberger, LM Restelli, ... The EMBO journal 32 (7), 1036-1051, 2013 | 44 | 2013 |
| Defective Sec61α1 underlies a novel cause of autosomal dominant severe congenital neutropenia E Van Nieuwenhove, JS Barber, J Neumann, E Smeets, M Willemsen, ... Journal of Allergy and Clinical Immunology 146 (5), 1180-1193, 2020 | 38 | 2020 |
| Identification of signal peptide features for substrate specificity in human Sec62/Sec63‐dependent ER protein import S Schorr, D Nguyen, S Haßdenteufel, N Nagaraj, A Cavalié, M Greiner, ... The FEBS journal 287 (21), 4612-4640, 2020 | 38 | 2020 |
| Complexity and specificity of Sec61-channelopathies: human diseases affecting gating of the Sec61 complex M Sicking, S Lang, F Bochen, A Roos, JPH Drenth, M Zakaria, ... Cells 10 (5), 1036, 2021 | 32 | 2021 |
| Live cell calcium imaging combined with siRNA mediated gene silencing identifies Ca2+ leak channels in the ER membrane and their regulatory mechanisms S Lang, N Schäuble, A Cavalié, R Zimmermann JoVE (Journal of Visualized Experiments), e2730, 2011 | 30 | 2011 |
| Lanthanum ions inhibit the mammalian Sec61 complex in its channel dynamics and protein transport activity F Erdmann, M Jung, S Eyrisch, S Lang, V Helms, R Wagner, ... FEBS letters 583 (14), 2359-2364, 2009 | 27 | 2009 |
