| Detailed analysis of grid‐based molecular docking: A case study of CDOCKER—A CHARMm‐based MD docking algorithm G Wu, DH Robertson, CL Brooks III, M Vieth Journal of computational chemistry 24 (13), 1549-1562, 2003 | 1541 | 2003 |
| Lessons in molecular recognition: the effects of ligand and protein flexibility on molecular docking accuracy JA Erickson, M Jalaie, DH Robertson, RA Lewis, M Vieth Journal of medicinal chemistry 47 (1), 45-55, 2004 | 479 | 2004 |
| Characteristic physical properties and structural fragments of marketed oral drugs M Vieth, MG Siegel, RE Higgs, IA Watson, DH Robertson, KA Savin, ... Journal of medicinal chemistry 47 (1), 224-232, 2004 | 434 | 2004 |
| Synthesis and activity of new aryl-and heteroaryl-substituted pyrazole inhibitors of the transforming growth factor-β type I receptor kinase domain JS Sawyer, BD Anderson, DW Beight, RM Campbell, ML Jones, ... Journal of medicinal chemistry 46 (19), 3953-3956, 2003 | 293 | 2003 |
| Kinomics—structural biology and chemogenomics of kinase inhibitors and targets M Vieth, RE Higgs, DH Robertson, M Shapiro, EA Gragg, H Hemmerle Biochimica et Biophysica Acta (BBA)-Proteins and Proteomics 1697 (1-2), 243-257, 2004 | 254 | 2004 |
| Assessing energy functions for flexible docking M Vieth, JD Hirst, A Kolinski, CL Brooks III Journal of Computational Chemistry 19 (14), 1612-1622, 1998 | 213 | 1998 |
| Kinomics: characterizing the therapeutically validated kinase space M Vieth, JJ Sutherland, DH Robertson, RM Campbell Drug discovery today 10 (12), 839-846, 2005 | 202 | 2005 |
| Assessing search strategies for flexible docking M Vieth, JD Hirst, BN Dominy, H Daigler, CL Brooks III Journal of computational chemistry 19 (14), 1623-1631, 1998 | 155 | 1998 |
| Molecular properties that influence oral drug-like behavior. MS Lajiness, M Vieth, J Erickson Current opinion in drug discovery & development 7 (4), 470-477, 2004 | 151 | 2004 |
| Lessons in molecular recognition. 2. Assessing and improving cross-docking accuracy JJ Sutherland, RK Nandigam, JA Erickson, M Vieth Journal of chemical information and modeling 47 (6), 2293-2302, 2007 | 134 | 2007 |
| Prediction of the folding pathways and structure of the GCN4 leucine zipper M Vieth, A Kolinski, CL Brooks III, J Skolnick Journal of molecular biology 237 (4), 361-367, 1994 | 132 | 1994 |
| Do active site conformations of small ligands correspond to low free-energy solution structures? M Vieth, JD Hirst, CL Brooks Journal of computer-aided molecular design 12, 563-572, 1998 | 126 | 1998 |
| Dependence of molecular properties on proteomic family for marketed oral drugs M Vieth, JJ Sutherland Journal of medicinal chemistry 49 (12), 3451-3453, 2006 | 116 | 2006 |
| Dynamic error correction in autocatalytic peptide networks K Severin, DH Lee, JA Martinez, M Vieth, MR Ghadiri Angewandte Chemie International Edition 37 (1‐2), 126-128, 1998 | 112 | 1998 |
| DoMCoSAR: A Novel Approach for Establishing the Docking Mode That Is Consistent with the Structure− Activity Relationship. Application to HIV-1 Protease Inhibitors and VEGF … M Vieth, DJ Cummins Journal of medicinal chemistry 43 (16), 3020-3032, 2000 | 100 | 2000 |
| Drugs in other drugs: a new look at drugs as fragments MG Siegel, M Vieth Drug discovery today 12 (1-2), 71-79, 2007 | 89 | 2007 |
| Chemical fragments as foundations for understanding target space and activity prediction JJ Sutherland, RE Higgs, I Watson, M Vieth Journal of medicinal chemistry 51 (9), 2689-2700, 2008 | 77 | 2008 |
| Design of potent and selective 2-aminobenzimidazole-based p38α MAP kinase inhibitors with excellent in vivo efficacy A de Dios, C Shih, B López de Uralde, C Sánchez, M del Prado, ... Journal of medicinal chemistry 48 (7), 2270-2273, 2005 | 68 | 2005 |
| SDOCKER: a method utilizing existing X-ray structures to improve docking accuracy G Wu, M Vieth Journal of medicinal chemistry 47 (12), 3142-3148, 2004 | 61 | 2004 |
| Structural insights into probe-dependent positive allosterism of the GLP-1 receptor AB Bueno, B Sun, FS Willard, D Feng, JD Ho, DB Wainscott, ... Nature Chemical Biology 16 (10), 1105-1110, 2020 | 60 | 2020 |
Charles L. Brooks IIICyrus Levinthal Distinguished University Professor of Chemistry and Biophysics; Warner-Lambert/ParkeVerified email at umich.edu
