| MicroRNA-146a alleviates chronic skin inflammation in atopic dermatitis through suppression of innate immune responses in keratinocytes A Rebane, T Runnel, A Aab, J Maslovskaja, B Rückert, M Zimmermann, ... Journal of allergy and clinical immunology 134 (4), 836-847. e11, 2014 | 188 | 2014 |
| Distribution of Wfs1 protein in the central nervous system of the mouse and its relation to clinical symptoms of the Wolfram syndrome H Luuk, S Koks, M Plaas, J Hannibal, JF Rehfeld, E Vasar Journal of Comparative Neurology 509 (6), 642-660, 2008 | 98 | 2008 |
| Wfs1-deficient mice display impaired behavioural adaptation in stressful environment H Luuk, M Plaas, S Raud, J Innos, S Sütt, H Lasner, U Abramov, ... Behavioural brain research 198 (2), 334-345, 2009 | 79 | 2009 |
| Transgenic animal model for modelling pathological anxiety, a method for identifying compounds for treatment of diseases or disorders caused by pathological anxiety and a … E Vasar, S Köks, H Luuk, S Raud, M Plaas US Patent App. 12/518,422, 2010 | 74 | 2010 |
| Wfs1 gene deletion causes growth retardation in mice and interferes with the growth hormone pathway S Koks, U Soomets, JL Paya-Cano, C Fernandes, H Luuk, M Plaas, ... Physiological genomics 37 (3), 249-259, 2009 | 61 | 2009 |
| Wfs1-deficient rats develop primary symptoms of Wolfram syndrome: insulin-dependent diabetes, optic nerve atrophy and medullary degeneration M Plaas, K Seppa, R Reimets, T Jagomäe, M Toots, T Koppel, T Vallisoo, ... Scientific reports 7 (1), 10220, 2017 | 48 | 2017 |
| Globin mRNA reduction for whole-blood transcriptome sequencing K Krjutškov, M Koel, AM Roost, S Katayama, E Einarsdottir, EM Jouhilahti, ... Scientific reports 6 (1), 31584, 2016 | 48 | 2016 |
| Relation between increased anxiety and reduced expression of alpha1 and alpha2 subunits of GABAA receptors in Wfs1-deficient mice S Raud, S Sütt, H Luuk, M Plaas, J Innos, S Kõks, E Vasar Neuroscience letters 460 (2), 138-142, 2009 | 46 | 2009 |
| Lower anxiety and a decrease in agonistic behaviour in Lsamp-deficient mice J Innos, MA Philips, E Leidmaa, I Heinla, S Raud, P Reemann, M Plaas, ... Behavioural brain research 217 (1), 21-31, 2011 | 44 | 2011 |
| Alpha-synuclein A30P point-mutation generates age-dependent nigrostriatal deficiency in ice M Plaas, A Karis, J Innos, E Rebane, V Baekelandt, A Vaarmann, H Luuk, ... Acta physiologica Polonica 59 (2), 205, 2008 | 43 | 2008 |
| GLP-1 receptor agonist liraglutide has a neuroprotective effect on an aged rat model of Wolfram syndrome K Seppa, M Toots, R Reimets, T Jagomäe, T Koppel, M Pallase, ... Scientific Reports 9 (1), 15742, 2019 | 38 | 2019 |
| Preventive treatment with liraglutide protects against development of glucose intolerance in a rat model of Wolfram syndrome M Toots, K Seppa, T Jagomäe, T Koppel, M Pallase, I Heinla, A Terasmaa, ... Scientific reports 8 (1), 10183, 2018 | 38 | 2018 |
| Expression of ric-8 (synembryn) gene in the nervous system of developing and adult mouse T Tõnissoo, R Meier, K Talts, M Plaas, A Karis Gene expression patterns 3 (5), 591-594, 2003 | 36 | 2003 |
| Animal model of Wolfram Syndrome in mice: behavioural, biochemical and psychopharmacological characterization M Plaas | 35 | 2013 |
| Heterozygous mice with Ric-8 mutation exhibit impaired spatial memory and decreased anxiety T Tõnissoo, S Kõks, R Meier, S Raud, M Plaas, E Vasar, A Karis Behavioural brain research 167 (1), 42-48, 2006 | 35 | 2006 |
| Mice Expressing Minimally Humanized CD81 and Occludin Genes Support Hepatitis C Virus Uptake In Vivo Q Ding, M von Schaewen, G Hrebikova, B Heller, L Sandmann, M Plaas, ... Journal of virology 91 (4), 10.1128/jvi. 01799-16, 2017 | 32 | 2017 |
| Trib3 is regulated by IL-3 and affects bone marrow-derived mast cell survival and function T Örd, D Örd, S Kuuse, M Plaas, T Örd Cellular Immunology 280 (1), 68-75, 2012 | 27 | 2012 |
| Exenatide Is an effective antihyperglycaemic agent in a mouse model of Wolfram syndrome 1 T Sedman, K Rünkorg, M Krass, H Luuk, M Plaas, E Vasar, V Volke Journal of diabetes research 2016, 2016 | 25 | 2016 |
| Evidence for impaired function of dopaminergic system in Wfs1-deficient mice T Visnapuu, M Plaas, R Reimets, S Raud, A Terasmaa, S Kõks, S Sütt, ... Behavioural brain research 244, 90-99, 2013 | 25 | 2013 |
| Liraglutide, 7, 8-DHF and their co-treatment prevents loss of vision and cognitive decline in a Wolfram syndrome rat model K Seppa, T Jagomäe, KG Kukker, R Reimets, M Pastak, E Vasar, ... Scientific Reports 11 (1), 2275, 2021 | 23 | 2021 |
