| The Parkinson's disease protein DJ-1 is neuroprotective due to cysteine-sulfinic acid-driven mitochondrial localization RM Canet-Avilés, MA Wilson, DW Miller, R Ahmad, C McLendon, ... Proceedings of the National Academy of Sciences 101 (24), 9103-9108, 2004 | 1390 | 2004 |
| Intrinsic motions along an enzymatic reaction trajectory KA Henzler-Wildman, V Thai, M Lei, M Ott, M Wolf-Watz, T Fenn, ... Nature 450 (7171), 838-844, 2007 | 1013 | 2007 |
| The oxidation state of DJ-1 regulates its chaperone activity toward α-synuclein W Zhou, M Zhu, MA Wilson, GA Petsko, AL Fink Journal of molecular biology 356 (4), 1036-1048, 2006 | 458 | 2006 |
| The 1.0 Å crystal structure of Ca2+-bound calmodulin: an analysis of disorder and implications for functionally relevant plasticity MA Wilson, AT Brunger Journal of molecular biology 301 (5), 1237-1256, 2000 | 389 | 2000 |
| The 1.1-Å resolution crystal structure of DJ-1, the protein mutated in autosomal recessive early onset Parkinson's disease MA Wilson, JL Collins, Y Hod, D Ringe, GA Petsko Proceedings of the National Academy of Sciences 100 (16), 9256-9261, 2003 | 381 | 2003 |
| The role of cysteine oxidation in DJ-1 function and dysfunction MA Wilson Antioxidants & redox signaling 15 (1), 111-122, 2011 | 347 | 2011 |
| Formation of a stabilized cysteine sulfinic acid is critical for the mitochondrial function of the parkinsonism protein DJ-1 J Blackinton, M Lakshminarasimhan, KJ Thomas, R Ahmad, E Greggio, ... Journal of Biological Chemistry 284 (10), 6476-6485, 2009 | 310 | 2009 |
| Reactive Oxygen Species in Chronic Obstructive Pulmonary Disease S Boukhenouna, MA Wilson, K Bahmed, B Kosmider Oxidative Medicine and Cellular Longevity, 2018 | 257 | 2018 |
| Cysteine p K a Depression by a Protonated Glutamic Acid in Human DJ-1†‡ AC Witt, M Lakshminarasimhan, BC Remington, S Hasim, E Pozharski, ... Biochemistry 47 (28), 7430-7440, 2008 | 151 | 2008 |
| Crystal cryocooling distorts conformational heterogeneity in a model Michaelis complex of DHFR DA Keedy, H Van Den Bedem, DA Sivak, GA Petsko, D Ringe, MA Wilson, ... Structure 22 (6), 899-910, 2014 | 147 | 2014 |
| The 1.8-Å resolution crystal structure of YDR533Cp from Saccharomyces cerevisiae: A member of the DJ-1/ThiJ/PfpI superfamily MA Wilson, CVS Amour, JL Collins, D Ringe, GA Petsko Proceedings of the National Academy of Sciences 101 (6), 1531-1536, 2004 | 131 | 2004 |
| 2.4 Å resolution crystal structure of the prototypical hormone-processing protease Kex2 in complex with an Ala-Lys-Arg boronic acid inhibitor T Holyoak, MA Wilson, TD Fenn, CA Kettner, GA Petsko, RS Fuller, ... Biochemistry 42 (22), 6709-6718, 2003 | 113 | 2003 |
| A glutathione-independent glyoxalase of the DJ-1 superfamily plays an important role in managing metabolically generated methylglyoxal in Candida albicans S Hasim, NA Hussin, F Alomar, KR Bidasee, KW Nickerson, MA Wilson Journal of Biological Chemistry 289 (3), 1662-1674, 2014 | 98 | 2014 |
| Toward resolving the catalytic mechanism of dihydrofolate reductase using neutron and ultrahigh-resolution X-ray crystallography Q Wan, BC Bennett, MA Wilson, A Kovalevsky, P Langan, EE Howell, ... Proceedings of the National Academy of Sciences 111 (51), 18225-18230, 2014 | 94 | 2014 |
| Identification of functional subclasses in the DJ-1 superfamily proteins Y Wei, D Ringe, MA Wilson, MJ Ondrechen PLoS computational biology 3 (1), e15, 2007 | 91 | 2007 |
| The atomic resolution crystal structure of the YajL (ThiJ) protein from Escherichia coli: a close prokaryotic homologue of the Parkinsonism-associated protein DJ-1 MA Wilson, D Ringe, GA Petsko Journal of molecular biology 353 (3), 678-691, 2005 | 81 | 2005 |
| Mix-and-inject XFEL crystallography reveals gated conformational dynamics during enzyme catalysis M Dasgupta, D Budday, SHP de Oliveira, P Madzelan, ... Proceedings of the National Academy of Sciences of the United States of …, 2019 | 78 | 2019 |
| Structural impact of three Parkinsonism-associated missense mutations on human DJ-1 M Lakshminarasimhan, MT Maldonado, W Zhou, AL Fink, MA Wilson Biochemistry 47 (5), 1381-1392, 2008 | 74 | 2008 |
| Crystal structure of dicamba monooxygenase: a Rieske nonheme oxygenase that catalyzes oxidative demethylation R Dumitru, WZ Jiang, DP Weeks, MA Wilson Journal of molecular biology 392 (2), 498-510, 2009 | 71 | 2009 |
| A Chemical Approach for the Detection of Protein Sulfinylation M Lo Conte, J Lin, MA Wilson, KS Carroll ACS chemical biology 10 (8), 1825-1830, 2015 | 70 | 2015 |
Greg PetskoProfessor of Neurology, Harvard Medical School and Brigham & Women's HospitalVerified email at bwh.harvard.edu
