Community assessment to advance computational prediction of cancer drug combinations in a pharmacogenomic screen MP Menden, D Wang, MJ Mason, B Szalai, KC Bulusu, Y Guan, T Yu, ... Nature communications 10 (1), 2674, 2019 | 275 | 2019 |
KLIFS: a structural kinase-ligand interaction database AJ Kooistra, GK Kanev, OPJ van Linden, R Leurs, IJP de Esch, C de Graaf Nucleic acids research 44 (D1), D365-D371, 2016 | 152 | 2016 |
The landscape of atypical and eukaryotic protein kinases GK Kanev, C de Graaf, IJP de Esch, R Leurs, T Würdinger, BA Westerman, ... Trends in pharmacological sciences 40 (11), 818-832, 2019 | 114 | 2019 |
KLIFS: an overhaul after the first 5 years of supporting kinase research GK Kanev, C de Graaf, BA Westerman, IJP de Esch, AJ Kooistra Nucleic acids research 49 (D1), D562-D569, 2021 | 97 | 2021 |
Crowdsourced mapping of unexplored target space of kinase inhibitors A Cichońska, B Ravikumar, RJ Allaway, F Wan, S Park, O Isayev, S Li, ... Nature communications 12 (1), 3307, 2021 | 63 | 2021 |
PDEStrIAn: a phosphodiesterase structure and ligand interaction annotated database as a tool for structure-based drug design C Jansen, AJ Kooistra, GK Kanev, R Leurs, IJP de Esch, C de Graaf Journal of medicinal chemistry 59 (15), 7029-7065, 2016 | 60 | 2016 |
Predicting the target landscape of kinase inhibitors using 3D convolutional neural networks GK Kanev, Y Zhang, AJ Kooistra, A Bender, R Leurs, D Bailey, ... PLoS computational biology 19 (9), e1011301, 2023 | 3 | 2023 |
1.15 - Structural Chemogenomics Databases to Navigate Protein–Ligand Interaction Space GK Kanev, AJ Kooistra, IJP de Esch, C de Graaf Comprehensive Medicinal Chemistry III 1, 444-471, 2017 | 3 | 2017 |
To Target or Not to Target Schistosoma mansoni Cyclic Nucleotide Phosphodiesterase 4A? Y Zheng, S Schroeder, GK Kanev, SS Botros, S William, ANA Sabra, ... International journal of molecular sciences 24 (7), 6817, 2023 | 1 | 2023 |
A Real-world Toxicity Atlas Shows that Adverse Events of Combination Therapies Commonly Result in Additive Interactions A Küçükosmanoglu, S Scoarta, M Houweling, N Spinu, T Wijnands, ... Clinical Cancer Research 30 (8), 1685-1695, 2024 | | 2024 |