Module map of stem cell genes guides creation of epithelial cancer stem cells DJ Wong, H Liu, TW Ridky, D Cassarino, E Segal, HY Chang Cell stem cell 2 (4), 333-344, 2008 | 809 | 2008 |
From keratinocyte to cancer: the pathogenesis and modeling of cutaneous squamous cell carcinoma V Ratushny, MD Gober, R Hick, TW Ridky, JT Seykora The Journal of clinical investigation 122 (2), 464-472, 2012 | 641 | 2012 |
p63 regulates proliferation and differentiation of developmentally mature keratinocytes AB Truong, M Kretz, TW Ridky, R Kimmel, PA Khavari Genes & development 20 (22), 3185-3197, 2006 | 551 | 2006 |
Selective vulnerability of cancer cells by inhibition of Ca2+ transfer from endoplasmic reticulum to mitochondria C Cárdenas, M Müller, A McNeal, A Lovy, F Jaňa, G Bustos, F Urra, ... Cell reports 14 (10), 2313-2324, 2016 | 251 | 2016 |
Invasive three-dimensional organotypic neoplasia from multiple normal human epithelia TW Ridky, JM Chow, DJ Wong, PA Khavari Nature medicine 16 (12), 1450-1455, 2010 | 232 | 2010 |
A dermal HOX transcriptional program regulates site-specific epidermal fate JL Rinn, JK Wang, N Allen, SA Brugmann, AJ Mikels, H Liu, TW Ridky, ... Genes & development 22 (3), 303-307, 2008 | 213 | 2008 |
Nonmelanoma skin cancer TW Ridky Journal of the American Academy of Dermatology 57 (3), 484-501, 2007 | 189 | 2007 |
Development of Drug Resistance to HIV-1 Protease Inhibitors∗ T Ridky, J Leis Journal of Biological Chemistry 270 (50), 29621-29623, 1995 | 160 | 1995 |
HMG protein family members stimulate human immunodeficiency virus type 1 and avian sarcoma virus concerted DNA integration in vitro P Hindmarsh, T Ridky, R Reeves, M Andrake, AM Skalka, J Leis Journal of virology 73 (4), 2994-3003, 1999 | 152 | 1999 |
MLL1 is essential for the senescence-associated secretory phenotype BC Capell, AM Drake, J Zhu, PP Shah, Z Dou, J Dorsey, DF Simola, ... Genes & development 30 (3), 321-336, 2016 | 146 | 2016 |
Sex steroids regulate skin pigmentation through nonclassical membrane-bound receptors CA Natale, EK Duperret, J Zhang, R Sadeghi, A Dahal, KT O'Brien, ... Elife 5, e15104, 2016 | 124 | 2016 |
Activation of G protein-coupled estrogen receptor signaling inhibits melanoma and improves response to immune checkpoint blockade CA Natale, J Li, J Zhang, A Dahal, T Dentchev, BZ Stanger, TW Ridky elife 7, e31770, 2018 | 120 | 2018 |
CDKN2B Loss Promotes Progression from Benign Melanocytic Nevus to Melanoma AS McNeal, K Liu, V Nakhate, CA Natale, EK Duperret, BC Capell, ... Cancer discovery 5 (10), 1072-1085, 2015 | 106 | 2015 |
Molecular properties of pyruvate formate-lyase activating enzyme KK Wong, BW Murray, SA Lewisch, MK Baxter, TW Ridky, ... Biochemistry 32 (51), 14102-14110, 1993 | 87 | 1993 |
Human Immunodeficiency Virus, Type 1 Protease Substrate Specificity Is Limited by Interactions between Substrate Amino Acids Bound in Adjacent Enzyme Subsites (∗) TW Ridky, CE Cameron, J Cameron, J Leis, T Copeland, A Wlodawer, ... Journal of Biological Chemistry 271 (9), 4709-4717, 1996 | 76 | 1996 |
Drug-resistant HIV-1 proteases identify enzyme residues important for substrate selection and catalytic rate TW Ridky, A Kikonyogo, J Leis, S Gulnik, T Copeland, J Erickson, ... Biochemistry 37 (39), 13835-13845, 1998 | 65 | 1998 |
Focal-adhesion-independent integrin-αv regulation of FAK and c-Myc is necessary for 3D skin formation and tumor invasion EK Duperret, A Dahal, TW Ridky Journal of cell science 128 (21), 3997-4013, 2015 | 61 | 2015 |
LSD1 inhibition promotes epithelial differentiation through derepression of fate-determining transcription factors S Egolf, Y Aubert, M Doepner, A Anderson, A Maldonado-Lopez, ... Cell reports 28 (8), 1981-1992. e7, 2019 | 59 | 2019 |
Lysosomes support the degradation, signaling, and mitochondrial metabolism necessary for human epidermal differentiation CL Monteleon, T Agnihotri, A Dahal, M Liu, VW Rebecca, GL Beatty, ... Journal of Investigative Dermatology 138 (9), 1945-1954, 2018 | 59 | 2018 |
Tumor necrosis factor receptor 1/c-Jun-NH2-kinase signaling promotes human neoplasia JY Zhang, AE Adams, TW Ridky, S Tao, PA Khavari Cancer research 67 (8), 3827-3834, 2007 | 59 | 2007 |