Model-based methods in the biopharmaceutical process lifecycle P Kroll, A Hofer, S Ulonska, J Kager, C Herwig Pharmaceutical research 34 (12), 2596-2613, 2017 | 78 | 2017 |
Impact of Glycerol as Carbon Source onto Specific Sugar and Inducer Uptake Rates and Inclusion Body Productivity in E. coli BL21(DE3) J Kopp, C Slouka, S Ulonska, J Kager, J Fricke, O Spadiut, C Herwig Bioengineering 5 (1), 1, 2017 | 71 | 2017 |
State estimation for a penicillin fed-batch process combining particle filtering methods with online and time delayed offline measurements J Kager, C Herwig, IV Stelzer Chemical Engineering Science 177, 234-244, 2018 | 38 | 2018 |
Experimental verification and comparison of model predictive, PID and model inversion control in a Penicillium chrysogenum fed-batch process J Kager, A Tuveri, S Ulonska, P Kroll, C Herwig Process biochemistry 90, 1-11, 2020 | 32 | 2020 |
Controlling the specific growth rate via biomass trend regulation in filamentous fungi bioprocesses D Ehgartner, T Hartmann, S Heinzl, M Frank, L Veiter, J Kager, C Herwig, ... Chemical Engineering Science 172, 32-41, 2017 | 27 | 2017 |
Model predictive control in comparison to elemental balance control in an E. coli fed-batch S Ulonska, D Waldschitz, J Kager, C Herwig Chemical Engineering Science 191, 459-467, 2018 | 26 | 2018 |
Noninvasive online monitoring of Corynebacterium glutamicum fed-batch bioprocesses subject to spent sulfite liquor raw material uncertainty P Sinner, M Stiegler, C Herwig, J Kager Bioresource Technology 321, 124395, 2021 | 22 | 2021 |
Probeless non-invasive near-infrared spectroscopic bioprocess monitoring using microspectrometer technology R Zimmerleiter, J Kager, R Nikzad-Langerodi, V Berezhinskiy, F Westad, ... Analytical and Bioanalytical Chemistry 412, 2103-2109, 2020 | 22 | 2020 |
Generic biomass estimation methods targeting physiologic process control in induced bacterial cultures WN Reichelt, P Thurrold, M Brillmann, J Kager, J Fricke, C Herwig Engineering in Life Sciences 16 (8), 720-730, 2016 | 21 | 2016 |
Inclusion Body Bead Size in E. coli Controlled by Physiological Feeding J Kopp, C Slouka, D Strohmer, J Kager, O Spadiut, C Herwig Microorganisms 6 (4), 116, 2018 | 20 | 2018 |
Comparison of particle filter and extended kalman filter algorithms for monitoring of bioprocesses IV Stelzer, J Kager, C Herwig Computer Aided Chemical Engineering 40, 1483-1488, 2017 | 20 | 2017 |
Advances in monitoring and control of refolding kinetics combining PAT and modeling JN Pauk, J Raju Palanisamy, J Kager, K Koczka, G Berghammer, ... Applied microbiology and biotechnology 105, 2243-2260, 2021 | 19 | 2021 |
Usage of digital twins along a typical process development cycle P Sinner, S Daume, C Herwig, J Kager Digital twins: Tools and concepts for smart biomanufacturing, 71-96, 2021 | 18 | 2021 |
Monitoring and control strategies for inclusion body production in E. coli based on glycerol consumption C Slouka, J Kopp, D Strohmer, J Kager, O Spadiut, C Herwig Journal of biotechnology 296, 75-82, 2019 | 18 | 2019 |
Establishing recombinant production of pediocin PA-1 in Corynebacterium glutamicum O Goldbeck, DN Desef, KV Ovchinnikov, F Perez-Garcia, J Christmann, ... Metabolic engineering 68, 34-45, 2021 | 16 | 2021 |
Generic workflow for the setup of mechanistic process models S Daume, S Kofler, J Kager, P Kroll, C Herwig Animal Cell Biotechnology: Methods and Protocols, 189-211, 2020 | 14 | 2020 |
Model-based analysis and optimisation of a continuous Corynebacterium glutamicum bioprocess utilizing lignocellulosic waste P Sinner, J Kager, S Daume, C Herwig IFAC-PapersOnLine 52 (26), 181-186, 2019 | 11 | 2019 |
A generic biomass soft sensor and its application in bioprocess development J Kager, J Fricke, U Becken, C Herwig, EAB Center Eppend-Appl Note 1, 2017 | 11 | 2017 |
Microbial technologies for biotherapeutics production: Key tools for advanced biopharmaceutical process development and control D Zalai, J Kopp, B Kozma, M Küchler, C Herwig, J Kager Drug Discovery Today: Technologies 38, 9-24, 2020 | 10 | 2020 |
Event driven modeling for the accurate identification of metabolic switches in fed-batch culture of S. cerevisiae MA Jouned, J Kager, C Herwig, T Barz Biochemical Engineering Journal 180, 108345, 2022 | 9 | 2022 |