Obserwuj
Andrew Kernytsky
Andrew Kernytsky
CRISPR Therapeutics
Zweryfikowany adres z crisprtx.com - Strona główna
Tytuł
Cytowane przez
Cytowane przez
Rok
The Genome Analysis Toolkit: a MapReduce framework for analyzing next-generation DNA sequencing data
A McKenna, M Hanna, E Banks, A Sivachenko, K Cibulskis, A Kernytsky, ...
Genome research 20 (9), 1297-1303, 2010
245782010
A framework for variation discovery and genotyping using next-generation DNA sequencing data
MA DePristo, E Banks, R Poplin, KV Garimella, JR Maguire, C Hartl, ...
Nature genetics 43 (5), 491-498, 2011
116212011
A map of human genome variation from population scale sequencing
1000 Genomes Project Consortium
Nature 467 (7319), 1061, 2010
87682010
CRISPR-Cas9 gene editing for sickle cell disease and β-thalassemia
H Frangoul, D Altshuler, MD Cappellini, YS Chen, J Domm, BK Eustace, ...
New England Journal of Medicine 384 (3), 252-260, 2021
12752021
An inhibitor of mutant IDH1 delays growth and promotes differentiation of glioma cells
D Rohle, J Popovici-Muller, N Palaskas, S Turcan, C Grommes, ...
Science 340 (6132), 626-630, 2013
12692013
Targeted inhibition of mutant IDH2 in leukemia cells induces cellular differentiation
F Wang, J Travins, B DeLaBarre, V Penard-Lacronique, S Schalm, ...
Science 340 (6132), 622-626, 2013
9422013
Exome sequencing, ANGPTL3 mutations, and familial combined hypolipidemia
K Musunuru, JP Pirruccello, R Do, GM Peloso, C Guiducci, C Sougnez, ...
New England Journal of Medicine 363 (23), 2220-2227, 2010
7782010
Demographic history and rare allele sharing among human populations
S Gravel, BM Henn, RN Gutenkunst, AR Indap, GT Marth, AG Clark, F Yu, ...
Proceedings of the National Academy of Sciences 108 (29), 11983-11988, 2011
7072011
Using multiple structure alignments, fast model building, and energetic analysis in fold recognition and homology modeling
D Petrey, Z Xiang, CL Tang, L Xie, M Gimpelev, T Mitros, CS Soto, ...
Proteins: Structure, Function, and Bioinformatics 53 (S6), 430-435, 2003
3952003
MTAP deletions in cancer create vulnerability to targeting of the MAT2A/PRMT5/RIOK1 axis
K Marjon, MJ Cameron, P Quang, MF Clasquin, E Mandley, K Kunii, ...
Cell reports 15 (3), 574-587, 2016
3432016
Transmembrane helix predictions revisited
CP Chen, A Kernytsky, B Rost
Protein Science 11 (12), 2774-2791, 2002
2702002
IDH2 mutation-induced histone and DNA hypermethylation is progressively reversed by small-molecule inhibition
A Kernytsky, F Wang, E Hansen, S Schalm, K Straley, C Gliser, H Yang, ...
Blood, The Journal of the American Society of Hematology 125 (2), 296-303, 2015
1812015
Membrane protein prediction methods
M Punta, LR Forrest, H Bigelow, A Kernytsky, J Liu, B Rost
Methods 41 (4), 460-474, 2007
1542007
Targeted exon sequencing by in‐solution hybrid selection
B Blumenstiel, K Cibulskis, S Fisher, M DeFelice, A Barry, T Fennell, ...
Current Protocols in Human Genetics 66 (1), 18.4. 1-18.4. 24, 2010
882010
Static benchmarking of membrane helix predictions
A Kernytsky, B Rost
Nucleic acids research 31 (13), 3642-3644, 2003
612003
Evaluation of homology-independent CRISPR-Cas9 off-target assessment methods
HG Chaudhari, J Penterman, HJ Whitton, SJ Spencer, N Flanagan, ...
The CRISPR Journal 3 (6), 440-453, 2020
432020
Using genetic algorithms to select most predictive protein features
A Kernytsky, B Rost
Proteins: Structure, Function, and Bioinformatics 75 (1), 75-88, 2009
272009
Altshuler, 695 D., Gabriel, S., Daly, M., et al.(2010). The Genome Analysis Toolkit: a MapReduce framework for analyzing 696 next-generation DNA sequencing data
A McKenna, M Hanna, E Banks, A Sivachenko, K Cibulskis, A Kernytsky, ...
Genome res 20, 1297-1303, 0
26*
CRISPR/Cas9 Genome Editing to Treat Sickle Cell Disease and B-Thalassemia: Re-Creating Genetic Variants to Upregulate Fetal Hemoglobin Appear Well-Tolerated, Effective and Durable.
MI Lin, E Paik, B Mishra, D Burkhardt, A Kernytsky, M Pettiglio, YS Chen, ...
Blood 130, 284, 2017
202017
A small molecule inhibitor of mutant IDH2 rescues cardiomyopathy in a D-2-hydroxyglutaric aciduria type II mouse model
F Wang, J Travins, Z Lin, Y Si, Y Chen, J Powe, S Murray, D Zhu, E Artin, ...
Journal of Inherited Metabolic Disease 39, 807-820, 2016
182016
Nie można teraz wykonać tej operacji. Spróbuj ponownie później.
Prace 1–20