| A Next Generation Connectivity Map: L1000 Platform and the First 1,000,000 Profiles Cell 171 (6), 1437–1452, 2017 | 2539 | 2017 |
| Flexible fitting of high-resolution x-ray structures into cryoelectron microscopy maps using biased molecular dynamics simulations M Orzechowski, F Tama Biophysical journal 95 (12), 5692-5705, 2008 | 123 | 2008 |
| Gestalt-Binding of tropomyosin on actin during thin filament activation W Lehman, M Orzechowski, XE Li, S Fischer, S Raunser Journal of muscle research and cell motility 34, 155-163, 2013 | 71 | 2013 |
| Three-dimensional organization of troponin on cardiac muscle thin filaments in the relaxed state S Yang, L Barbu-Tudoran, M Orzechowski, R Craig, J Trinick, H White, ... Biophysical journal 106 (4), 855-864, 2014 | 67 | 2014 |
| An atomic model of the tropomyosin cable on F-actin M Orzechowski, XE Li, S Fischer, W Lehman Biophysical journal 107 (3), 694-699, 2014 | 64 | 2014 |
| Energy landscapes reveal the myopathic effects of tropomyosin mutations M Orzechowski, S Fischer, JR Moore, W Lehman, GP Farman Archives of Biochemistry and Biophysics 564, 89-99, 2014 | 56 | 2014 |
| Biased coarse-grained molecular dynamics simulation approach for flexible fitting of X-ray structure into cryo electron microscopy maps I Grubisic, MN Shokhirev, M Orzechowski, O Miyashita, F Tama Journal of structural biology 169 (1), 95-105, 2010 | 54 | 2010 |
| SARS‐CoV‐2 antibody persistence in COVID‐19 convalescent plasma donors: dependency on assay format and applicability to serosurveillance C Di Germanio, G Simmons, K Kelly, R Martinelli, O Darst, M Azimpouran, ... Transfusion 61 (9), 2677-2687, 2021 | 50 | 2021 |
| Structure and flexibility of the tropomyosin overlap junction XE Li, M Orzechowski, W Lehman, S Fischer Biochemical and biophysical research communications 446 (1), 304-308, 2014 | 41 | 2014 |
| Tropomyosin movement on F-actin during muscle activation explained by energy landscapes M Orzechowski, JR Moore, S Fischer, W Lehman Archives of biochemistry and biophysics 545, 63-68, 2014 | 38 | 2014 |
| Mechanical unfolding of the beet western yellow virus− 1 frameshift signal KH White, M Orzechowski, D Fourmy, K Visscher Journal of the American Chemical Society 133 (25), 9775-9782, 2011 | 34 | 2011 |
| Electrostatic interaction map reveals a new binding position for tropomyosin on F-actin MJ Rynkiewicz, V Schott, M Orzechowski, W Lehman, S Fischer Journal of muscle research and cell motility 36, 525-533, 2015 | 32 | 2015 |
| The structural dynamics of alpha-tropomyosin on F-actin shape the overlap complex between adjacent tropomyosin molecules W Lehman, X Li, M Orzechowski, S Fischer Biophysical Journal 106 (2), 769a, 2014 | 28 | 2014 |
| Application of steered molecular dynamics (SMD) to study DNA–drug complexes and probing helical propensity of amino acids M Orzechowski, P Cieplak Journal Of Physics: Condensed Matter 17 (18), S1627, 2005 | 28 | 2005 |
| HCM and DCM cardiomyopathy-linked α-tropomyosin mutations influence off-state stability and crossbridge interaction on thin filaments GP Farman, MJ Rynkiewicz, M Orzechowski, W Lehman, JR Moore Archives of biochemistry and biophysics 647, 84-92, 2018 | 24 | 2018 |
| Large-Scale Chemical-Genetic Strategy Enables the Design of Antimicrobial Combination Chemotherapy in Mycobacteria EO Johnson, E Office, T Kawate, M Orzechowski, DT Hung ACS infectious diseases 6 (1), 56-63, 2019 | 13 | 2019 |
| Dynamics of Water Filaments in Disordered Environments M Orzechowski, M Meuwly The Journal of Physical Chemistry B 114 (38), 12203-12212, 2010 | 13 | 2010 |
| Theoretical calculation of the coiled‐coil stability in water in the context of its possible use as a molecular rack M Orzechowski, P Cieplak, L Piela Journal of computational chemistry 23 (1), 106-110, 2002 | 11 | 2002 |
| Influence of actin mutation on the energy landscape of actin-tropomyosin filaments M Orzechowski, S Fischer, W Lehman Biophysical Journal 104 (2), 480a, 2013 | 5 | 2013 |
| High-throughput neutralization and serology assays reveal correlated but highly variable humoral immune responses in a large population of individuals infected with SARS-CoV-2 … S Zhang, P Ma, M Orzechowski, A Lemmer, K Rzasa, J Bagnall, S Barkho, ... Mbio 14 (2), e03523-22, 2023 | 4 | 2023 |
Jeffrey R. MooreProfessor of Biological SciencesVerified email at uml.edu
