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Paul William Finn
Paul William Finn
Oxford Drug Design Limited, University of Buckingham, Affinity Drug Design
Zweryfikowany adres z oxforddrugdesign.com
Tytuł
Cytowane przez
Cytowane przez
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Determination of the class and isoform selectivity of small-molecule histone deacetylase inhibitors
N Khan, M Jeffers, S Kumar, C Hackett, F Boldog, N Khramtsov, X Qian, ...
Biochemical Journal 409 (2), 581-589, 2008
8672008
Pharmacodynamic response and inhibition of growth of human tumor xenografts by the novel histone deacetylase inhibitor PXD101
JA Plumb, PW Finn, RJ Williams, MJ Bandara, MR Romero, CJ Watkins, ...
Molecular cancer therapeutics 2 (8), 721-728, 2003
4522003
Quantitative proteomic analysis of post-translational modifications of human histones
HC Beck, EC Nielsen, R Matthiesen, LH Jensen, M Sehested, P Finn, ...
Molecular & Cellular Proteomics 5 (7), 1314-1325, 2006
2362006
Combined inhibition of DNA methylation and histone acetylation enhances gene re-expression and drug sensitivity in vivo
N Steele, P Finn, R Brown, JA Plumb
British journal of cancer 100 (5), 758-763, 2009
1902009
Pharmacophore discovery using the inductive logic programming system Progol
P Finn, S Muggleton, D Page, A Srinivasan
Machine Learning 30, 241-270, 1998
1721998
Carbamic acid compounds comprising an amide linkage as HDAC inhibitors
A Amolins, V Andrianov, RM Bokaldere, K Dikovska, JES Duffy, PW Finn, ...
US Patent 7,880,020, 2011
123*2011
ElectroShape: fast molecular similarity calculations incorporating shape, chirality and electrostatics
MS Armstrong, GM Morris, PW Finn, R Sharma, L Moretti, RI Cooper, ...
Journal of computer-aided molecular design 24, 789-801, 2010
1162010
Carbamic acid compounds comprising an amide linkage as hdac inhibitors
A Amolins, V Andrianov, RM Bokaldere, K Dikovska, JES Duffy, PW Finn, ...
US Patent App. 12/983,971, 2011
111*2011
Carbamic acid compounds comprising an amide linkage as HDAC inhibitors
A Amolins, V Andrianov, RM Bokaldere, K Dikovska, JES Duffy, PW Finn, ...
US Patent 7,569,724, 2009
110*2009
RAPID: Randomized pharmacophore identification for drug design
PW Finn, LE Kavraki, JC Latombe, M R, C Shelton, ...
Computational Geometry: Theory and Applications 4 (10), 263-272, 1998
981998
Carbamic acid compounds comprising a sulfonamide linkage as HDAC inhibitors
CJ Watkins, MR Romero-Martin, KG Moore, J Ritchie, PW Finn, I Kalvinsh, ...
US Patent 6,888,027, 2005
972005
Ultrafast shape recognition: evaluating a new ligand-based virtual screening technology
PJ Ballester, PW Finn, WG Richards
Journal of Molecular Graphics and Modelling 27 (7), 836-845, 2009
962009
The cell cycle, chromatin and cancer: mechanism-based therapeutics come of age
F McLaughlin, P Finn, NB La Thangue
Drug discovery today 8 (17), 793-802, 2003
872003
Carbamic acid compounds comprising an ether linkage as HDAC inhibitors
RM Bokaldere, JES Duffy, PW Finn, CJ Harris, I Kalvinsh, D Lolya, E Loza, ...
US Patent 6,960,685, 2005
83*2005
Computational approaches to drug design
PW Finn, LE Kavraki
Algorithmica 25, 347-371, 1999
801999
Novel sulfonamide derivatives as inhibitors of histone deacetylase
PW Finn, M Bandara, C Butcher, A Finn, R Hollinshead, N Khan, N Law, ...
Helvetica Chimica Acta 88 (7), 1630-1657, 2005
752005
Plasmodium subtilisin-like protease 1 (SUB1): insights into the active-site structure, specificity and function of a pan-malaria drug target
C Withers-Martinez, C Suarez, S Fulle, S Kher, M Penzo, JP Ebejer, ...
International journal for parasitology 42 (6), 597-612, 2012
632012
A randomized kinematics‐based approach to pharmacophore‐constrained conformational search and database screening
SM LaValle, PW Finn, LE Kavraki, JC Latombe
Journal of Computational Chemistry 21 (9), 731-747, 2000
622000
Epigenetic approaches to cancer therapy
JA Plumb, N Steele, PW Finn, R Brown
Biochemical Society Transactions 32 (6), 1095-1097, 2004
572004
Improving the accuracy of ultrafast ligand-based screening: incorporating lipophilicity into ElectroShape as an extra dimension
MS Armstrong, PW Finn, GM Morris, WG Richards
Journal of computer-aided molecular design 25, 785-790, 2011
562011
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