Vitaliy Sviripa
Vitaliy Sviripa
Research Assistant Professor, University of Kentucky
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Identification of unique mechanisms for triterpene biosynthesis in Botryococcus braunii
TD Niehaus, S Okada, TP Devarenne, DS Watt, V Sviripa, J Chappell
Proceedings of the National Academy of Sciences 108 (30), 12260-12265, 2011
Arylquins target vimentin to trigger Par-4 secretion for tumor cell apoptosis
R Burikhanov, VM Sviripa, N Hebbar, W Zhang, WJ Layton, A Hamza, ...
Nature chemical biology 10 (11), 924-926, 2014
Fluorinated N,N-Dialkylaminostilbenes Repress Colon Cancer by Targeting Methionine S-Adenosyltransferase 2A
W Zhang, V Sviripa, X Chen, J Shi, T Yu, A Hamza, ND Ward, LM Kril, ...
ACS chemical biology 8 (4), 796-803, 2013
Fluorinated N,N-Dialkylaminostilbenes for Wnt Pathway Inhibition and Colon Cancer Repression
W Zhang, V Sviripa, LM Kril, X Chen, T Yu, J Shi, P Rychahou, BM Evers, ...
Journal of medicinal chemistry 54 (5), 1288-1297, 2011
2′, 6′-Dihalostyrylanilines, pyridines, and pyrimidines for the inhibition of the catalytic subunit of methionine S-adenosyltransferase-2
VM Sviripa, W Zhang, AG Balia, OV Tsodikov, JR Nickell, F Gizard, T Yu, ...
Journal of medicinal Chemistry 57 (14), 6083-6091, 2014
Application of Mannich bases to the synthesis of hydroxymethylated isoflavonoids as potential antineoplastic agents
MS Frasinyuk, GP Mrug, SP Bondarenko, VM Sviripa, W Zhang, X Cai, ...
Organic & biomolecular chemistry 13 (46), 11292-11301, 2015
Original approach to new derivatives of [1, 3] oxazolo [4, 5-d] pyrimidine
VM Sviripa, AA Gakh, VS Brovarets, AV Gutov, BS Drach
Synthesis 2006 (20), 3462-3466, 2006
Antineoplastic Isoflavonoids Derived from Intermediate ortho‐Quinone Methides Generated from Mannich Bases
MS Frasinyuk, GP Mrug, SP Bondarenko, VP Khilya, VM Sviripa, ...
ChemMedChem 11 (6), 600-611, 2016
Synthesis and tautomerization of hydroxylated isoflavones bearing heterocyclic hemi-aminals
MS Frasinyuk, SP Bondarenko, VP Khilya, C Liu, DS Watt, VM Sviripa
Organic & biomolecular chemistry 13 (4), 1053-1067, 2015
Synthesis and characterization of pseudocantharidins, novel phosphatase modulators that promote the inclusion of exon 7 into the SMN (survival of motoneuron) pre-mRNA
Z Zhang, O Kelemen, MA van Santen, SM Yelton, AE Wendlandt, ...
Journal of Biological Chemistry 286 (12), 10126-10136, 2011
Developing antineoplastic agents that target peroxisomal enzymes: cytisine-linked isoflavonoids as inhibitors of hydroxysteroid 17-beta-dehydrogenase-4 (HSD17B4)
MS Frasinyuk, W Zhang, P Wyrebek, T Yu, X Xu, VM Sviripa, ...
Organic & biomolecular chemistry 15 (36), 7623-7629, 2017
Fluorinated N,N′-diarylureas as AMPK activators
V Sviripa, W Zhang, MD Conroy, ES Schmidt, AX Liu, J Truong, C Liu, ...
Bioorganic & medicinal chemistry letters 23 (6), 1600-1603, 2013
One-Pot Synthesis of B-Ring Ortho-Hydroxylated Sappanin-Type Homoisoflavonoids
GP Mrug, NV Myshko, SP Bondarenko, VM Sviripa, MS Frasinyuk
The Journal of organic chemistry 84 (11), 7138-7147, 2019
Par-4 secretion: stoichiometry of 3-arylquinoline binding to vimentin
VM Sviripa, R Burikhanov, JM Obiero, Y Yuan, JR Nickell, LP Dwoskin, ...
Organic & biomolecular chemistry 14 (1), 74-84, 2016
Semisynthetic aurones inhibit tubulin polymerization at the colchicine-binding site and repress PC-3 tumor xenografts in nude mice and myc-induced T-ALL in zebrafish
Y Xie, LM Kril, T Yu, W Zhang, MS Frasinyuk, SP Bondarenko, ...
Scientific Reports 9 (1), 6439, 2019
Induction of AMPK activation by N,N’-diarylurea FND-4b decreases growth and increases apoptosis in triple negative and estrogen-receptor positive breast cancers
J Johnson, P Rychahou, VM Sviripa, HL Weiss, C Liu, DS Watt, BM Evers
PLoS One 14 (3), e0209392, 2019
Analysis of trans-2,6-difluoro-4′-(N,N-dimethylamino)stilbene (DFS) in biological samples by liquid chromatography-tandem mass spectrometry: metabolite …
SCM Yeo, VM Sviripa, M Huang, L Kril, DS Watt, C Liu, HS Lin
Analytical and bioanalytical chemistry 407, 7319-7332, 2015
An underlying mechanism of dual Wnt inhibition and AMPK activation: mitochondrial uncouplers masquerading as Wnt inhibitors
W Zhang, VM Sviripa, LM Kril, T Yu, Y Xie, WB Hubbard, PG Sullivan, ...
Journal of medicinal chemistry 62 (24), 11348-11358, 2019
Bis (N-amidinohydrazones) and N-(amidino)-N′-aryl-bishydrazones: New classes of antibacterial/antifungal agents
SK Shrestha, LM Kril, KD Green, S Kwiatkowski, VM Sviripa, JR Nickell, ...
Bioorganic & medicinal chemistry 25 (1), 58-66, 2017
A crystal structure of coil 1B of vimentin in the filamentous form provides a model of a high‐order assembly of a vimentin filament
AH Pang, JM Obiero, AW Kulczyk, VM Sviripa, OV Tsodikov
The FEBS journal 285 (15), 2888-2899, 2018
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