| Intratumor heterogeneity in human glioblastoma reflects cancer evolutionary dynamics A Sottoriva, I Spiteri, SGM Piccirillo, A Touloumis, VP Collins, JC Marioni, ... Proceedings of the National Academy of Sciences 110 (10), 4009-4014, 2013 | 1888 | 2013 |
| Bone morphogenetic proteins inhibit the tumorigenic potential of human brain tumour-initiating cells SGM Piccirillo, BA Reynolds, N Zanetti, G Lamorte, E Binda, G Broggi, ... Nature 444 (7120), 761-765, 2006 | 1436 | 2006 |
| NOTCH pathway blockade depletes CD133-positive glioblastoma cells and inhibits growth of tumor neurospheres and xenografts X Fan, L Khaki, TS Zhu, ME Soules, CE Talsma, N Gul, C Koh, J Zhang, ... Stem cells 28 (1), 5-16, 2010 | 790 | 2010 |
| Cyclopamine-mediated hedgehog pathway inhibition depletes stem-like cancer cells in glioblastoma EE Bar, A Chaudhry, A Lin, X Fan, K Schreck, W Matsui, S Piccirillo, ... Stem cells 25 (10), 2524-2533, 2007 | 763 | 2007 |
| Acetate is a bioenergetic substrate for human glioblastoma and brain metastases T Mashimo, K Pichumani, V Vemireddy, KJ Hatanpaa, DK Singh, ... Cell 159 (7), 1603-1614, 2014 | 690 | 2014 |
| Distinct pools of cancer stem-like cells coexist within human glioblastomas and display different tumorigenicity and independent genomic evolution SGM Piccirillo, R Combi, L Cajola, A Patrizi, S Redaelli, A Bentivegna, ... Oncogene 28 (15), 1807-1811, 2009 | 223 | 2009 |
| Cisplatin-tethered gold nanospheres for multimodal chemo-radiotherapy of glioblastoma S Setua, M Ouberai, SG Piccirillo, C Watts, M Welland Nanoscale 6 (18), 10865-10873, 2014 | 137 | 2014 |
| Fluorescence-guided surgical sampling of glioblastoma identifies phenotypically distinct tumour-initiating cell populations in the tumour mass and margin SGM Piccirillo, S Dietz, B Madhu, J Griffiths, SJ Price, VP Collins, C Watts British journal of cancer 107 (3), 462-468, 2012 | 128 | 2012 |
| DNER, an Epigenetically Modulated Gene, Regulates Glioblastoma-Derived Neurosphere Cell Differentiation and Tumor Propagation P Sun, S Xia, B Lal, CG Eberhart, A Quinones-Hinojosa, J Maciaczyk, ... Stem cells 27 (7), 1473-1486, 2009 | 104 | 2009 |
| EGFRvIII mutations can emerge as late and heterogenous events in glioblastoma development and promote angiogenesis through Src activation E Eskilsson, GV Rosland, KM Talasila, S Knappskog, O Keunen, ... Neuro-oncology 18 (12), 1644-1655, 2016 | 103 | 2016 |
| Brain cancer stem cells SGM Piccirillo, E Binda, R Fiocco, AL Vescovi, K Shah Journal of molecular medicine 87, 1087-1095, 2009 | 96 | 2009 |
| Bone morphogenetic proteins regulate tumorigenicity in human glioblastoma stem cells SGM Piccirillo, AL Vescovi Cancer Stem Cells: Novel Concepts and Prospects for Tumor Therapy, 59-81, 2007 | 95 | 2007 |
| Oncogenes Activate an Autonomous Transcriptional Regulatory Circuit That Drives Glioblastoma BRM Singh DK, Kollipara RK, Vemireddy V, Yang XL, Sun Y, Regmi N, Klingler S ... Cell Reports 18 (4), 961-976, 2017 | 90 | 2017 |
| Glioblastoma cell growth is suppressed by disruption of Fibroblast Growth Factor pathway signaling W Loilome, AD Joshi, CMJ Ap Rhys, S Piccirillo, VL Angelo, GL Gallia, ... Journal of neuro-oncology 94, 359-366, 2009 | 89 | 2009 |
| Genetic and functional diversity of propagating cells in glioblastoma SGM Piccirillo, S Colman, NE Potter, FW Van Delft, S Lillis, MJ Carnicer, ... Stem cell reports 4 (1), 7-15, 2015 | 83 | 2015 |
| NG2 expression in glioblastoma identifies an actively proliferating population with an aggressive molecular signature MTF Al-Mayhani, R Grenfell, M Narita, S Piccirillo, E Kenney-Herbert, ... Neuro-oncology 13 (8), 830-845, 2011 | 78 | 2011 |
| Gliomas interact with non-glioma brain cells via extracellular vesicles X Gao, Z Zhang, T Mashimo, B Shen, J Nyagilo, H Wang, Y Wang, Z Liu, ... Cell reports 30 (8), 2489-2500. e5, 2020 | 73 | 2020 |
| Contributions to drug resistance in glioblastoma derived from malignant cells in the sub-ependymal zone SGM Piccirillo, I Spiteri, A Sottoriva, A Touloumis, S Ber, SJ Price, ... Cancer research 75 (1), 194-202, 2015 | 67 | 2015 |
| Evolutionary dynamics of residual disease in human glioblastoma I Spiteri, G Caravagna, GD Cresswell, A Vatsiou, D Nichol, A Acar, ... Annals of Oncology 30 (3), 456-463, 2019 | 65 | 2019 |
| Brain tumour stem cells: possibilities of new therapeutic strategies SGM Piccirillo, AL Vescovi Expert opinion on biological therapy 7 (8), 1129-1135, 2007 | 61 | 2007 |
