Mihalis Kariolis
Mihalis Kariolis
Denali Therapeutics
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Cited by
Direct regulation of GAS6/AXL signaling by HIF promotes renal metastasis through SRC and MET
EB Rankin, KC Fuh, L Castellini, K Viswanathan, EC Finger, AN Diep, ...
Proceedings of the National Academy of Sciences 111 (37), 13373-13378, 2014
Brain delivery of therapeutic proteins using an Fc fragment blood-brain barrier transport vehicle in mice and monkeys
MS Kariolis, RC Wells, JA Getz, W Kwan, CS Mahon, R Tong, DJ Kim, ...
Science translational medicine 12 (545), eaay1359, 2020
Reprogramming the immunological microenvironment through radiation and targeting Axl
TA Aguilera, M Rafat, L Castellini, H Shehade, MS Kariolis, ABY Hui, ...
Nature communications 7 (1), 13898, 2016
Carbon nanotubes increase the electrical conductivity of fibroblast-seeded collagen hydrogels
RA MacDonald, CM Voge, M Kariolis, JP Stegemann
Acta biomaterialia 4 (6), 1583-1592, 2008
An engineered Axl'decoy receptor'effectively silences the Gas6-Axl signaling axis
MS Kariolis, YR Miao, DS Jones, S Kapur, II Mathews, AJ Giaccia, ...
Nature chemical biology 10 (11), 977-983, 2014
Brain delivery and activity of a lysosomal enzyme using a blood-brain barrier transport vehicle in mice
JC Ullman, A Arguello, JA Getz, A Bhalla, CS Mahon, J Wang, T Giese, ...
Science Translational Medicine 12 (545), eaay1163, 2020
Inhibition of the GAS6/AXL pathway augments the efficacy of chemotherapies
MS Kariolis, YR Miao, A Diep, SE Nash, MM Olcina, D Jiang, DS Jones, ...
The Journal of clinical investigation 127 (1), 183-198, 2017
Rescue of a lysosomal storage disorder caused by Grn loss of function with a brain penetrant progranulin biologic
T Logan, MJ Simon, A Rana, GM Cherf, A Srivastava, SS Davis, RLY Low, ...
Cell 184 (18), 4651-4668. e25, 2021
Directional conductivity in SWNT‐collagen‐fibrin composite biomaterials through strain‐induced matrix alignment
CM Voge, M Kariolis, RA MacDonald, JP Stegemann
Journal of Biomedical Materials Research Part A: An Official Journal of The …, 2008
Beyond antibodies: using biological principles to guide the development of next-generation protein therapeutics
MS Kariolis, S Kapur, JR Cochran
Current opinion in biotechnology 24 (6), 1072-1077, 2013
Inhibition of AXL signaling in anti-metastatic therapy
AJ Giaccia, EB Rankin, JR Cochran, D Jones, M Kariolis, K Fuh, Y Miao
US Patent 8,618,254, 2013
Cystine‐knot peptides engineered with specificities for αIIbβ3 or αIIbβ3 and αvβ3 integrins are potent inhibitors of platelet aggregation
AP Silverman, MS Kariolis, JR Cochran
Journal of Molecular Recognition 24 (1), 127-135, 2011
Molecular architecture determines brain delivery of a transferrin receptor–targeted lysosomal enzyme
A Arguello, CS Mahon, MEK Calvert, D Chan, JC Dugas, ME Pizzo, ...
Journal of Experimental Medicine 219 (3), e20211057, 2022
Neutralization of PD-L2 is essential for overcoming immune checkpoint blockade resistance in ovarian cancer
YR Miao, KN Thakkar, J Qian, MS Kariolis, W Huang, S Nandagopal, ...
Clinical cancer research 27 (15), 4435-4448, 2021
Engineering high affinity protein–protein interactions using a high-throughput microcapillary array platform
S Lim, B Chen, MS Kariolis, IK Dimov, TM Baer, JR Cochran
ACS Chemical Biology 12 (2), 336-341, 2017
Engineered polypeptides
X Chen, M Kariolis, RC Wells
US Patent 10,457,717, 2019
Cystine knot peptides binding to alpha IIb beta 3 integrins and methods of use
JR Cochran, AP Silverman, MS Kariolis
US Patent 8,778,888, 2014
Induced tumor heterogeneity reveals factors informing radiation and immunotherapy combinations
TA Aguilera, EA Elghonaimy, H Shehade, M Rafat, L Castellini, D Jiang, ...
Clinical Cancer Research 26 (12), 2972-2985, 2020
31st annual meeting and associated programs of the society for immunotherapy of cancer (Sitc 2016): Part two: National harbor, md, USA. 9-13 November 2016
C Ager, M Reilley, C Nicholas, T Bartkowiak, A Jaiswal, M Curran, ...
Journal for ImmunoTherapy of Cancer 4, 107-221, 2016
Inhibition of AXL signaling in anti-metastatic therapy
AJ Giaccia, EB Rankin, JR Cochran, D Jones, M Kariolis, K Fuh, Y Miao
US Patent 9,074,192, 2015
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