Oscillations and bistability in the stochastic model of p53 regulation K Puszyński, B Hat, T Lipniacki
Journal of theoretical biology 254 (2), 452-465, 2008
125 2008 Single TNFα trimers mediating NF-κ B activation: stochastic robustness of NF-κ B signaling T Lipniacki, K Puszynski, P Paszek, AR Brasier, M Kimmel
BMC bioinformatics 8, 1-20, 2007
97 2007 Cell cycle as an object of control A Świerniak, M Kimmel, J Smieja, K Puszynski, K Psiuk-Maksymowicz, ...
System Engineering Approach to Planning Anticancer Therapies, 9-54, 2016
94 2016 Crosstalk between p53 and nuclear factor-κB systems: pro-and anti-apoptotic functions of NF-κB K Puszynski, R Bertolusso, T Lipniacki
IET systems biology 3 (5), 356-367, 2009
58 2009 A novel mathematical model of ATM/p53/NF- κ B pathways points to the importance of the DDR switch-off mechanisms K Jonak, M Kurpas, K Szoltysek, P Janus, A Abramowicz, K Puszynski
BMC systems biology 10, 1-12, 2016
45 2016 The pharmacodynamics of the p53-Mdm2 targeting drug Nutlin: the role of gene-switching noise K Puszynski, A Gandolfi, A d'Onofrio
PLoS computational biology 10 (12), e1003991, 2014
45 2014 System engineering approach to planning anticancer therapies A Świerniak, M Kimmel, J Smieja, K Puszynski, K Psiuk-Maksymowicz
Springer International Publishing, 2016
30 2016 Exploring mechanisms of oscillations in p53 and nuclear factor-κB systems B Hat, K Puszynski, T Lipniacki
IET Systems Biology 3 (5), 342-355, 2009
29 2009 Application of bifurcation theory and siRNA-based control signal to restore the proper response of cancer cells to DNA damage E Kozłowska, K Puszynski
Journal of Theoretical Biology 408, 213-221, 2016
18 2016 Regulation of p53 by siRNA in radiation treated cells: Simulation studies K Puszyński, R Jaksik, A Świerniak
International Journal of Applied Mathematics and Computer Science 22 (4 …, 2012
17 2012 Sensitivity analysis of deterministic signaling pathways models K Puszyński, P Lachor, M Kardyńska, J Śmieja
Bulletin of the Polish Academy of Sciences. Technical Sciences 60 (3), 471-479, 2012
17 2012 Integrated system supporting research on environment related cancers W Bensz, D Borys, K Fujarewicz, K Herok, R Jaksik, M Krasucki, ...
Recent Developments in Intelligent Information and Database Systems, 399-409, 2016
9 2016 Multiple epidemic waves as the outcome of stochastic SIR epidemics with behavioral responses: a hybrid modeling approach M Ochab, P Manfredi, K Puszynski, A d’Onofrio
Nonlinear Dynamics 111 (1), 887-926, 2023
8 2023 Petri nets and ODEs as complementary methods for comprehensive analysis on an example of the ATM–p53–NF- B signaling pathways K Gutowska, D Kogut, M Kardynska, P Formanowicz, J Smieja, ...
Scientific Reports 12 (1), 1135, 2022
8 2022 Application of image processing algorithms in proteomics: automatic analysis of 2-d gel electrophoresis images from western blot assay K Jonak, K Jędrasiak, A Polański, K Puszyński
Computer Vision and Graphics: International Conference, ICCVG 2012, Warsaw …, 2012
8 2012 The role of stochastic gene switching in determining the pharmacodynamics of certain drugs: basic mechanisms K Puszynski, A Gandolfi, A d’Onofrio
Journal of pharmacokinetics and pharmacodynamics 43, 395-410, 2016
7 2016 Application of the piece-wise linear models for description of nonlinear biological systems based on p53 regulatory unit M Ochab, K Puszynski, A Swierniak
Proceedings of the XXI National Conference on Applications of Mathematics in …, 2016
7 2016 Deterministic models and stochastic simulations in multiple reaction models in systems biology P Laroch, K Puszynski, A Polanski
BioTechnologia. Journal of Biotechnology Computational Biology and …, 2011
7 2011 Variety behavior in the piece-wise linear model of the p53-regulatory module M Ochab, K Puszynski, A Swierniak, J Klamka
Bioinformatics and Biomedical Engineering: 5th International Work-Conference …, 2017
5 2017 Application of sensitivity analysis to discover potential molecular drug targets M Kardynska, J Smieja, P Paszek, K Puszynski
International Journal of Molecular Sciences 23 (12), 6604, 2022
4 2022