| EGFR Mutations in Lung Cancer: Correlation with Clinical Response to Gefitinib Therapy JG Paez, PA Janne, JC Lee, S Tracy, H Greulich, S Gabriel, P Herman, ... Science 304 (5676), 1497-1500, 2004 | 11970 | 2004 |
| Signatures of mutational processes in human cancer LB Alexandrov, S Nik-Zainal, DC Wedge, SAJR Aparicio, S Behjati, ... Nature 500 (7463), 415-421, 2013 | 9817 | 2013 |
| Integrated genomic analysis identifies clinically relevant subtypes of glioblastoma characterized by abnormalities in PDGFRA, IDH1, EGFR, and NF1 RGW Verhaak, KA Hoadley, E Purdom, V Wang, Y Qi, MD Wilkerson, ... Cancer cell 17 (1), 98-110, 2010 | 7867 | 2010 |
| The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity J Barretina, G Caponigro, N Stransky, K Venkatesan, AA Margolin, S Kim, ... Nature 483 (7391), 603-607, 2012 | 7732 | 2012 |
| Comprehensive molecular characterization of human colon and rectal cancer Cancer Genome Atlas Network Nature 487 (7407), 330, 2012 | 7419 | 2012 |
| Comprehensive genomic characterization defines human glioblastoma genes and core pathways Cancer Genome Atlas Research Network Tissue source sites: Duke University ... Nature 455 (7216), 1061-1068, 2008 | 7346 | 2008 |
| Integrated genomic analyses of ovarian carcinoma Cancer Genome Atlas Research Network Nature 474 (7353), 609, 2011 | 6844 | 2011 |
| Mutational heterogeneity in cancer and the search for new cancer-associated genes MS Lawrence, P Stojanov, P Polak, GV Kryukov, K Cibulskis, ... Nature 499 (7457), 214-218, 2013 | 5781 | 2013 |
| Comprehensive molecular characterization of gastric adenocarcinoma Cancer Genome Atlas Research Network Nature 513 (7517), 202, 2014 | 5136 | 2014 |
| The somatic genomic landscape of glioblastoma CW Brennan, RGW Verhaak, A McKenna, B Campos, H Noushmehr, ... cell 155 (2), 462-477, 2013 | 4954 | 2013 |
| Integrated genomic characterization of endometrial carcinoma DA Levine, ... Nature 497 (7447), 67-73, 2013 | 4834 | 2013 |
| EGFR Mutation and Resistance of Non–Small-Cell Lung Cancer to Gefitinib S Kobayashi, TJ Boggon, T Dayaram, PA Jänne, O Kocher, M Meyerson, ... New England Journal of Medicine 352 (8), 786-792, 2005 | 4776 | 2005 |
| Sensitive detection of somatic point mutations in impure and heterogeneous cancer samples K Cibulskis, MS Lawrence, SL Carter, A Sivachenko, D Jaffe, C Sougnez, ... Nature biotechnology 31 (3), 213-219, 2013 | 4771 | 2013 |
| Genomic and epigenomic landscapes of adult de novo acute myeloid leukemia Cancer Genome Atlas Research Network New England Journal of Medicine 368 (22), 2059-2074, 2013 | 4641 | 2013 |
| The immune landscape of cancer V Thorsson, DL Gibbs, SD Brown, D Wolf, DS Bortone, THO Yang, ... Immunity 48 (4), 812-830. e14, 2018 | 4413 | 2018 |
| The landscape of somatic copy-number alteration across human cancers R Beroukhim, CH Mermel, D Porter, G Wei, S Raychaudhuri, J Donovan, ... Nature 463 (7283), 899-905, 2010 | 4220 | 2010 |
| Activating mutation in the tyrosine kinase JAK2 in polycythemia vera, essential thrombocythemia, and myeloid metaplasia with myelofibrosis RL Levine, M Wadleigh, J Cools, BL Ebert, G Wernig, BJP Huntly, ... Cancer cell 7 (4), 387-397, 2005 | 3830 | 2005 |
| Comprehensive molecular profiling of lung adenocarcinoma Cancer Genome Atlas Research Network Nature 511 (7511), 543, 2014 | 3825 | 2014 |
| Comprehensive genomic characterization of squamous cell lung cancers Cancer Genome Atlas Research Network Nature 489 (7417), 519, 2012 | 3659 | 2012 |
| Discovery and saturation analysis of cancer genes across 21 tumour types MS Lawrence, P Stojanov, CH Mermel, JT Robinson, LA Garraway, ... Nature 505 (7484), 495-501, 2014 | 3204 | 2014 |
