Design, power, and interpretation of studies in the standard murine model of ALS S Scott, JE Kranz, J Cole, JM Lincecum, K Thompson, N Kelly, A Bostrom, ... Amyotrophic Lateral Sclerosis 9 (1), 4-15, 2008 | 551 | 2008 |
Guidelines for preclinical animal research in ALS/MND: A consensus meeting AC Ludolph, C Bendotti, E Blaugrund, A Chio, L Greensmith, JP Loeffler, ... Amyotrophic Lateral Sclerosis 11 (1-2), 38-45, 2010 | 330 | 2010 |
From transcriptome analysis to therapeutic anti-CD40L treatment in the SOD1 model of amyotrophic lateral sclerosis JM Lincecum, FG Vieira, MZ Wang, K Thompson, GS De Zutter, J Kidd, ... Nature genetics 42 (5), 392-399, 2010 | 130 | 2010 |
Personalizing ASR for dysarthric and accented speech with limited data J Shor, D Emanuel, O Lang, O Tuval, M Brenner, J Cattiau, F Vieira, ... arXiv preprint arXiv:1907.13511, 2019 | 107 | 2019 |
C57BL/6J congenic Prp-TDP43A315T mice develop progressive neurodegeneration in the myenteric plexus of the colon without exhibiting key features of ALS T Hatzipetros, LP Bogdanik, VR Tassinari, JD Kidd, AJ Moreno, C Davis, ... Brain research 1584, 59-72, 2014 | 107 | 2014 |
No benefit from chronic lithium dosing in a sibling-matched, gender balanced, investigator-blinded trial using a standard mouse model of familial ALS A Gill, J Kidd, F Vieira, K Thompson, S Perrin PLoS One 4 (8), e6489, 2009 | 100 | 2009 |
A quick phenotypic neurological scoring system for evaluating disease progression in the SOD1-G93A mouse model of ALS T Hatzipetros, JD Kidd, AJ Moreno, K Thompson, A Gill, FG Vieira JoVE (Journal of Visualized Experiments), e53257, 2015 | 99 | 2015 |
Degeneration of proprioceptive sensory nerve endings in mice harboring amyotrophic lateral sclerosis–causing mutations SK Vaughan, Z Kemp, T Hatzipetros, F Vieira, G Valdez Journal of Comparative Neurology 523 (17), 2477-2494, 2015 | 85 | 2015 |
Guanabenz treatment accelerates disease in a mutant SOD1 mouse model of ALS FG Vieira, Q Ping, AJ Moreno, JD Kidd, K Thompson, B Jiang, ... PloS one 10 (8), e0135570, 2015 | 79 | 2015 |
SOD1-positive aggregate accumulation in the CNS predicts slower disease progression and increased longevity in a mutant SOD1 mouse model of ALS C Gill, JP Phelan, T Hatzipetros, JD Kidd, VR Tassinari, B Levine, ... Scientific reports 9 (1), 6724, 2019 | 74 | 2019 |
A human-derived antibody targets misfolded SOD1 and ameliorates motor symptoms in mouse models of amyotrophic lateral sclerosis M Maier, T Welt, F Wirth, F Montrasio, D Preisig, J McAfoose, FG Vieira, ... Science translational medicine 10 (470), eaah3924, 2018 | 73 | 2018 |
Phase IIa trial of fingolimod for amyotrophic lateral sclerosis demonstrates acceptable acute safety and tolerability JD Berry, S Paganoni, N Atassi, EA Macklin, N Goyal, M Rivner, ... Muscle & nerve 56 (6), 1077-1084, 2017 | 47 | 2017 |
Proteomic analysis reveals differentially regulated protein acetylation in human amyotrophic lateral sclerosis spinal cord D Liu, C Liu, J Li, K Azadzoi, Y Yang, Z Fei, K Dou, NW Kowall, HP Choi, ... PLoS One 8 (12), e80779, 2013 | 41 | 2013 |
CuATSM efficacy is independently replicated in a SOD1 mouse model of ALS while unmetallated ATSM therapy fails to reveal benefits FG Vieira, T Hatzipetros, K Thompson, AJ Moreno, JD Kidd, VR Tassinari, ... IBRO reports 2, 47-53, 2017 | 34 | 2017 |
The ALS-inducing factors, TDP43A315T and SOD1G93A, directly affect and sensitize sensory neurons to stress SK Vaughan, NM Sutherland, S Zhang, T Hatzipetros, F Vieira, G Valdez Scientific Reports 8 (1), 16582, 2018 | 25 | 2018 |
Dexpramipexole is ineffective in two models of ALS related neurodegeneration FG Vieira, E LaDow, A Moreno, JD Kidd, B Levine, K Thompson, A Gill, ... PLoS One 9 (12), e91608, 2014 | 25 | 2014 |
A machine-learning based objective measure for ALS disease severity FG Vieira, S Venugopalan, AS Premasiri, M McNally, A Jansen, ... NPJ digital medicine 5 (1), 45, 2022 | 18 | 2022 |
Method for the treatment of neurodegenerative diseases S Perrin, JM Lincecum, A Gill, F Vieira US Patent 8,435,514, 2013 | 15 | 2013 |
Type I PRMT inhibition protects against C9ORF72 arginine-rich dipeptide repeat toxicity AS Premasiri, AL Gill, FG Vieira Frontiers in Pharmacology 11, 569661, 2020 | 12 | 2020 |
Primary neurons and differentiated NSC-34 cells are more susceptible to arginine-rich ALS dipeptide repeat protein-associated toxicity than non-differentiated NSC-34 and CHO cells AL Gill, MZ Wang, B Levine, A Premasiri, FG Vieira International Journal of Molecular Sciences 20 (24), 6238, 2019 | 11 | 2019 |