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Long Shuang Huang
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mtDNA activates cGAS signaling and suppresses the YAP-mediated endothelial cell proliferation program to promote inflammatory injury
LS Huang, Z Hong, W Wu, S Xiong, M Zhong, X Gao, J Rehman, AB Malik
Immunity 52 (3), 475-486. e5, 2020
2502020
Sphingosine-1–phosphate, FTY720, and Sphingosine-1–phosphate receptors in the pathobiology of acute lung injury
V Natarajan, SM Dudek, JR Jacobson, L Moreno-Vinasco, LS Huang, ...
American journal of respiratory cell and molecular biology 49 (1), 6-17, 2013
1542013
The sphingosine kinase 1/sphingosine-1-phosphate pathway in pulmonary arterial hypertension
J Chen, H Tang, JR Sysol, L Moreno-Vinasco, KM Shioura, T Chen, ...
American journal of respiratory and critical care medicine 190 (9), 1032-1043, 2014
1352014
IL-1β suppression of VE-cadherin transcription underlies sepsis-induced inflammatory lung injury
S Xiong, Z Hong, LS Huang, Y Tsukasaki, S Nepal, A Di, M Zhong, W Wu, ...
The Journal of clinical investigation 130 (7), 3684-3698, 2020
1322020
Targeting sphingosine kinase 1 attenuates bleomycin-induced pulmonary fibrosis
LS Huang, E Berdyshev, B Mathew, P Fu, IA Gorshkova, D He, W Ma, ...
The FASEB Journal 27 (4), 1749-1760, 2013
1002013
Lysophosphatidic acid receptor–2 deficiency confers protection against bleomycin-induced lung injury and fibrosis in mice
LS Huang, P Fu, P Patel, A Harijith, T Sun, Y Zhao, JGN Garcia, J Chun, ...
American journal of respiratory cell and molecular biology 49 (6), 912-922, 2013
922013
Sphingosine kinase 1/S1P signaling contributes to pulmonary fibrosis by activating Hippo/YAP pathway and mitochondrial reactive oxygen species in lung fibroblasts
LS Huang, T Sudhadevi, P Fu, PK Punathil-Kannan, DL Ebenezer, ...
International journal of molecular sciences 21 (6), 2064, 2020
822020
Sphingosine-1-phosphate lyase is an endogenous suppressor of pulmonary fibrosis: role of S1P signalling and autophagy
LS Huang, EV Berdyshev, JT Tran, L Xie, J Chen, DL Ebenezer, ...
Thorax 70 (12), 1138-1148, 2015
752015
Sphingolipids in pulmonary fibrosis
LS Huang, V Natarajan
Advances in biological regulation 57, 55-63, 2015
742015
The angiocrine Rspondin3 instructs interstitial macrophage transition via metabolic–epigenetic reprogramming and resolves inflammatory injury
B Zhou, L Magana, Z Hong, LS Huang, S Chakraborty, Y Tsukasaki, ...
Nature immunology 21 (11), 1430-1443, 2020
692020
Lysophosphatidylcholine Containing Docosahexaenoic Acid at the sn-1 Position is Anti-inflammatory
LS Huang, ND Hung, DE Sok, MR Kim
Lipids 45, 225-236, 2010
612010
The mitochondrial cardiolipin remodeling enzyme lysocardiolipin acyltransferase is a novel target in pulmonary fibrosis
LS Huang, B Mathew, H Li, Y Zhao, SF Ma, I Noth, SP Reddy, A Harijith, ...
American journal of respiratory and critical care medicine 189 (11), 1402-1415, 2014
572014
Protective action of honokiol, administered orally, against oxidative stress in brain of mice challenged with NMDA
HS Cui, LS Huang, DE Sok, J Shin, BM Kwon, UJ Youn, K Bae
Phytomedicine 14 (10), 696-700, 2007
572007
Sphingosine kinase 1 deficiency confers protection against hyperoxia-induced bronchopulmonary dysplasia in a murine model: role of S1P signaling and Nox proteins
A Harijith, S Pendyala, NM Reddy, T Bai, PV Usatyuk, E Berdyshev, ...
The American journal of pathology 183 (4), 1169-1182, 2013
542013
Lysocardiolipin acyltransferase regulates TGF-β mediated lung fibroblast differentiation
LS Huang, P Jiang, C Feghali-Bostwick, SP Reddy, JGN Garcia, ...
Free Radical Biology and Medicine 112, 162-173, 2017
332017
Sphingolipids in ventilator induced lung injury: role of sphingosine-1-phosphate lyase
V Suryadevara, P Fu, DL Ebenezer, E Berdyshev, IA Bronova, LS Huang, ...
International Journal of Molecular Sciences 19 (1), 114, 2018
322018
Phosphatidic acid produced by RalA-activated PLD2 stimulates caveolae-mediated endocytosis and trafficking in endothelial cells
Y Jiang, MS Sverdlov, PT Toth, LS Huang, G Du, Y Liu, V Natarajan, ...
Journal of Biological Chemistry 291 (39), 20729-20738, 2016
322016
Role of phospholipase D in bleomycin-induced mitochondrial reactive oxygen species generation, mitochondrial DNA damage, and pulmonary fibrosis
V Suryadevara, L Huang, SJ Kim, P Cheresh, M Shaaya, M Bandela, P Fu, ...
American Journal of Physiology-Lung Cellular and Molecular Physiology, 2019
312019
Linoleoyl lysophosphatidylcholine is an efficient substrate for soybean lipoxygenase-1
LS Huang, MR Kim, DE Sok
Archives of biochemistry and biophysics 455 (2), 119-126, 2006
302006
Oxygenation of arachidonoyl lysophospholipids by lipoxygenases from soybean, porcine leukocyte, or rabbit reticulocyte
LS Huang, JS Kang, MR Kim, DE Sok
Journal of agricultural and food chemistry 56 (4), 1224-1232, 2008
292008
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