| NADPH oxidases: key modulators in aging and age-related cardiovascular diseases? S Sahoo, DN Meijles, PJ Pagano Clinical Science 130 (5), 317-335, 2016 | 166 | 2016 |
| The quest for selective nox inhibitors and therapeutics: challenges, triumphs and pitfalls E Cifuentes-Pagano, DN Meijles, PJ Pagano Antioxidants & redox signaling 20 (17), 2741-2754, 2014 | 98 | 2014 |
| Molecular insights of p47phox phosphorylation dynamics in the regulation of NADPH oxidase activation and superoxide production DN Meijles, LM Fan, BJ Howlin, JM Li Journal of Biological Chemistry 289 (33), 22759-22770, 2014 | 74 | 2014 |
| The matricellular protein TSP1 promotes human and mouse endothelial cell senescence through CD47 and Nox1 DN Meijles, S Sahoo, I Al Ghouleh, JH Amaral, R Bienes-Martinez, ... Science signaling 10 (501), eaaj1784, 2017 | 73 | 2017 |
| MEF2C-MYOCD and leiomodin1 suppression by miRNA-214 promotes smooth muscle cell phenotype switching in pulmonary arterial hypertension S Sahoo, DN Meijles, I Al Ghouleh, M Tandon, E Cifuentes-Pagano, ... PLoS One 11 (5), e0153780, 2016 | 64 | 2016 |
| Redox regulation of cardiac ASK1 (apoptosis signal-regulating kinase 1) controls p38-MAPK (mitogen-activated protein kinase) and orchestrates cardiac remodeling to hypertension DN Meijles, JJ Cull, T Markou, STE Cooper, ZHR Haines, SJ Fuller, ... Hypertension 76 (4), 1208-1218, 2020 | 59 | 2020 |
| Nox inhibitors & therapies: rational design of peptidic and small molecule inhibitors M Eugenia Cifuentes-Pagano, D N Meijles, P J Pagano Current pharmaceutical design 21 (41), 6032-6035, 2015 | 59 | 2015 |
| Nox and inflammation in the vascular adventitia DN Meijles, PJ Pagano Hypertension 67 (1), 14-19, 2016 | 57 | 2016 |
| Endothelial Nox1 oxidase assembly in human pulmonary arterial hypertension; driver of Gremlin1-mediated proliferation IA Ghouleh, S Sahoo, DN Meijles, JH Amaral, DS de Jesus, J Sembrat, ... Clinical Science 131 (15), 2019-2035, 2017 | 52 | 2017 |
| Selective inactivation of NADPH oxidase 2 causes regression of vascularization and the size and stability of atherosclerotic plaques IM Quesada, A Lucero, C Amaya, DN Meijles, ME Cifuentes, PJ Pagano, ... Atherosclerosis 242 (2), 469-475, 2015 | 52 | 2015 |
| Vascular TSP1-CD47 signaling promotes sickle cell-associated arterial vasculopathy and pulmonary hypertension in mice EM Novelli, L Little-Ihrig, HE Knupp, NM Rogers, M Yao, JJ Baust, ... American Journal of Physiology-Lung Cellular and Molecular Physiology 316 (6 …, 2019 | 45 | 2019 |
| NADPH oxidase 2 inhibitors CPP11G and CPP11H attenuate endothelial cell inflammation & vessel dysfunction and restore mouse hind-limb flow Y Li, E Cifuentes-Pagano, ER DeVallance, DS De Jesus, S Sahoo, ... Redox biology 22, 101143, 2019 | 40 | 2019 |
| Nox2-derived ROS in PPARγ signaling and cell-cycle progression of lung alveolar epithelial cells J Tickner, LM Fan, J Du, D Meijles, JM Li Free Radical Biology and Medicine 51 (3), 763-772, 2011 | 38 | 2011 |
| Binding of EBP50 to Nox organizing subunit p47phox is pivotal to cellular reactive species generation and altered vascular phenotype I Al Ghouleh, DN Meijles, S Mutchler, Q Zhang, S Sahoo, A Gorelova, ... Proceedings of the National Academy of Sciences 113 (36), E5308-E5317, 2016 | 35 | 2016 |
| CD47 and Nox1 mediate dynamic fluid-phase macropinocytosis of native LDL G Csányi, DM Feck, P Ghoshal, B Singla, H Lin, S Nagarajan, DN Meijles, ... Antioxidants & Redox Signaling 26 (16), 886-901, 2017 | 32 | 2017 |
| Divergent Effects of p47phox Phosphorylation at S303-4 or S379 on Tumor Necrosis Factor-α Signaling via TRAF4 and MAPK in Endothelial Cells L Teng, LM Fan, D Meijles, JM Li Arteriosclerosis, thrombosis, and vascular biology 32 (6), 1488-1496, 2012 | 32 | 2012 |
| Consensus in silico computational modelling of the p22phox subunit of the NADPH oxidase DN Meijles, BJ Howlin, JM Li Computational biology and chemistry 39, 6-13, 2012 | 31 | 2012 |
| The cardiomyocyte “redox rheostat”: Redox signalling via the AMPK-mTOR axis and regulation of gene and protein expression balancing survival and death DN Meijles, G Zoumpoulidou, T Markou, KA Rostron, R Patel, K Lay, ... Journal of molecular and cellular cardiology 129, 118-129, 2019 | 28 | 2019 |
| Pharmacologic targeting of renal ischemia-reperfusion injury using a normothermic machine perfusion platform AM Hameed, DB Lu, H Burns, N Byrne, YV Chew, S Julovi, K Ghimire, ... Scientific Reports 10 (1), 6930, 2020 | 24 | 2020 |
| p22phox C242T Single-Nucleotide Polymorphism Inhibits Inflammatory Oxidative Damage to Endothelial Cells and Vessels DN Meijles, LM Fan, MM Ghazaly, B Howlin, M Krönke, G Brooks, JM Li Circulation 133 (24), 2391-2403, 2016 | 20 | 2016 |
Patrick PaganoProfessor of Pharmacology & Chemical Biology, PI in the Vascular Medicine InstituteVerified email at pitt.edu
