| Selective VPS34 inhibitor blocks autophagy and uncovers a role for NCOA4 in ferritin degradation and iron homeostasis in vivo WE Dowdle, B Nyfeler, J Nagel, RA Elling, S Liu, E Triantafellow, ... Nature cell biology 16 (11), 1069-1079, 2014 | 701 | 2014 |
| Tension directly stabilizes reconstituted kinetochore-microtubule attachments B Akiyoshi, KK Sarangapani, AF Powers, CR Nelson, SL Reichow, ... Nature 468 (7323), 576-579, 2010 | 516 | 2010 |
| The Ndc80 kinetochore complex forms load-bearing attachments to dynamic microtubule tips via biased diffusion AF Powers, AD Franck, DR Gestaut, J Cooper, B Gracyzk, RR Wei, ... Cell 136 (5), 865-875, 2009 | 335 | 2009 |
| The Dam1 kinetochore complex harnesses microtubule dynamics to produce force and movement CL Asbury, DR Gestaut, AF Powers, AD Franck, TN Davis Proceedings of the National Academy of Sciences 103 (26), 9873-9878, 2006 | 236 | 2006 |
| Inhibition of DYRK1A and GSK3B induces human β-cell proliferation W Shen, B Taylor, Q Jin, V Nguyen-Tran, S Meeusen, YQ Zhang, ... Nature communications 6 (1), 8372, 2015 | 231 | 2015 |
| Tension applied through the Dam1 complex promotes microtubule elongation providing a direct mechanism for length control in mitosis AD Franck, AF Powers, DR Gestaut, T Gonen, TN Davis, CL Asbury Nature cell biology 9 (7), 832-837, 2007 | 197 | 2007 |
| Angiotensin II injures the arterial wall causing increased aortic stiffening in apolipoprotein E-deficient mice DM Tham, B Martin-McNulty, YX Wang, V Da Cunha, DW Wilson, ... American Journal of Physiology-Regulatory, Integrative and Comparative …, 2002 | 86 | 2002 |
| Direct physical study of kinetochore–microtubule interactions by reconstitution and interrogation with an optical force clamp AD Franck, AF Powers, DR Gestaut, TN Davis, CL Asbury Methods 51 (2), 242-250, 2010 | 56 | 2010 |
| Synergistic effect of angiotensin II and nitric oxide synthase inhibitor in increasing aortic stiffness in mice RM Fitch, JC Rutledge, YX Wang, AF Powers, JL Tseng, T Clary, ... American Journal of Physiology-Heart and Circulatory Physiology 290 (3 …, 2006 | 52 | 2006 |
| OMA1 mediates local and global stress responses against protein misfolding in CHCHD10 mitochondrial myopathy MK Shammas, X Huang, BP Wu, E Fessler, IY Song, NP Randolph, Y Li, ... The Journal of Clinical Investigation 132 (14), 2022 | 46 | 2022 |
| Prevention and regression of megamitochondria and steatosis by blocking mitochondrial fusion in the liver T Yamada, D Murata, DE Kleiner, R Anders, AZ Rosenberg, J Kaplan, ... Iscience 25 (4), 2022 | 20 | 2022 |
| A novel and translational role for autophagy in antisense oligonucleotide trafficking and activity J Ochaba, AF Powers, KA Tremble, S Greenlee, NM Post, JE Matson, ... Nucleic acids research 47 (21), 11284-11303, 2019 | 16 | 2019 |
| Apolipoprotein E3-and Nitric Oxide–Dependent Modulation of Endothelial Cell Inflammatory Responses AE Mullick, AF Powers, RS Kota, SD Tetali, JP Eiserich, JC Rutledge Arteriosclerosis, thrombosis, and vascular biology 27 (2), 339-345, 2007 | 13 | 2007 |
| Mouse genome-wide association studies and systems genetics uncover the genetic architecture associated with hepatic pharmacokinetic and pharmacodynamic properties of a … E Pirie, S Ray, C Pan, W Fu, AF Powers, D Polikoff, CM Miller, KM Kudrna, ... PLoS genetics 14 (10), e1007732, 2018 | 6 | 2018 |
| Measuring Kinetochore–Microtubule Interaction In Vitro JW Driver, AF Powers, KK Sarangapani, S Biggins, CL Asbury Methods in enzymology 540, 321-337, 2014 | 6 | 2014 |
| Hyperglycemia and loss of ovarian hormones mediate atheroma formation through endothelial layer disruption and increased permeability J Benton, A Powers, L Eiselein, R Fitch, D Wilson, AC Villablanca, ... American Journal of Physiology-Regulatory, Integrative and Comparative …, 2007 | 6 | 2007 |
| The Ndc80 kinetochore complex uses biased diffusion to couple chromosomes to dynamic microtubule tips AF Powers, AD Franck, DR Gestaut, J Cooper, B Gracyzk, RR Wei, ... Cell 136 (5), 865, 2009 | 5 | 2009 |
| Antisense oligonucleotide-mediated silencing of mitochondrial fusion and fission factors modulates mitochondrial dynamics and rescues mitochondrial dysfunction DA Garcia, AF Powers, TA Bell 3rd, S Guo, M Aghajan nucleic acid therapeutics 32 (1), 51-65, 2022 | 3 | 2022 |
| 2066-P: Dyrk1a Antisense Oligonucleotides Conjugated to GLP-1R Agonist Promote Pancreatic Beta-Cell Proliferation W Fu, R Lee, EC Pirie, T Prakash, S Murray, A Powers, AE Mullick, ... Diabetes 69 (Supplement_1), 2020 | | 2020 |
| 2143-P: GLP-1 Conjugation Enhances the Activity of Antisense Oligonucleotides Targeting Islet Amyloid Polypeptide (IAPP) or Kelch-Like ECH Associated Protein 1 (Keap1) in … W Fu, R Lee, EC Pirie, T Prakash, S Murray, AF Powers, RM Crooke Diabetes 68 (Supplement_1), 2019 | | 2019 |
Charles L AsburyUniversity of Washington, Physiology & BiophysicsZweryfikowany adres z uw.edu
