| The target landscape of clinical kinase drugs S Klaeger, S Heinzlmeir, M Wilhelm, H Polzer, B Vick, PA Koenig, ... Science 358 (6367), eaan4368, 2017 | 736 | 2017 |
| K+ efflux-independent NLRP3 inflammasome activation by small molecules targeting mitochondria CJ Groß, R Mishra, KS Schneider, G Médard, J Wettmarshausen, ... Immunity 45 (4), 761-773, 2016 | 420 | 2016 |
| The inflammasome drives GSDMD-independent secondary pyroptosis and IL-1 release in the absence of caspase-1 protease activity KS Schneider, CJ Groß, RF Dreier, BS Saller, R Mishra, O Gorka, R Heilig, ... Cell reports 21 (13), 3846-3859, 2017 | 248 | 2017 |
| DMSO enhances electrospray response, boosting sensitivity of proteomic experiments H Hahne, F Pachl, B Ruprecht, SK Maier, S Klaeger, D Helm, G Médard, ... Nature methods 10 (10), 989-991, 2013 | 248 | 2013 |
| Optimized chemical proteomics assay for kinase inhibitor profiling G Médard, F Pachl, B Ruprecht, S Klaeger, S Heinzlmeir, D Helm, H Qiao, ... Journal of proteome research 14 (3), 1574-1586, 2015 | 136 | 2015 |
| Comprehensive and reproducible phosphopeptide enrichment using iron immobilized metal ion affinity chromatography (Fe-IMAC) columns B Ruprecht, H Koch, G Medard, M Mundt, B Kuster, S Lemeer Molecular & Cellular Proteomics 14 (1), 205-215, 2015 | 132 | 2015 |
| Systematic identification of MCU modulators by orthogonal interspecies chemical screening DM Arduino, J Wettmarshausen, H Vais, P Navas-Navarro, Y Cheng, ... Molecular cell 67 (4), 711-723. e7, 2017 | 110 | 2017 |
| Chemical proteomics reveals ferrochelatase as a common off-target of kinase inhibitors S Klaeger, B Gohlke, J Perrin, V Gupta, S Heinzlmeir, D Helm, H Qiao, ... ACS chemical biology 11 (5), 1245-1254, 2016 | 97 | 2016 |
| N-Heterocyclic carbenes on close-packed coinage metal surfaces: bis-carbene metal adatom bonding scheme of monolayer films on Au, Ag and Cu L Jiang, B Zhang, G Médard, AP Seitsonen, F Haag, F Allegretti, ... Chemical Science 8 (12), 8301-8308, 2017 | 91 | 2017 |
| ProteomeTools: Systematic characterization of 21 post-translational protein modifications by liquid chromatography tandem mass spectrometry (LC-MS/MS) using synthetic peptides DP Zolg, M Wilhelm, T Schmidt, G Médard, J Zerweck, T Knaute, ... Molecular & Cellular Proteomics 17 (9), 1850-1863, 2018 | 81 | 2018 |
| Chemical proteomics uncovers EPHA2 as a mechanism of acquired resistance to small molecule EGFR kinase inhibition H Koch, MEDC Busto, K Kramer, G Médard, B Kuster Journal of proteome research 14 (6), 2617-2625, 2015 | 60 | 2015 |
| Label-free quantitative proteome analysis of the surface-bound salivary pellicle J Delius, S Trautmann, G Médard, B Kuster, M Hannig, T Hofmann Colloids and Surfaces B: Biointerfaces 152, 68-76, 2017 | 56 | 2017 |
| Chemical proteomics and structural biology define EPHA2 inhibition by clinical kinase drugs S Heinzlmeir, D Kudlinzki, S Sreeramulu, S Klaeger, SL Gande, V Linhard, ... ACS chemical biology 11 (12), 3400-3411, 2016 | 54 | 2016 |
| Target deconvolution of HDAC pharmacopoeia reveals MBLAC2 as common off-target S Lechner, MIP Malgapo, C Grätz, RR Steimbach, A Baron, P Rüther, ... Nature chemical biology 18 (8), 812-820, 2022 | 47 | 2022 |
| Evaluation of kinase activity profiling using chemical proteomics B Ruprecht, J Zecha, S Heinzlmeir, G Medard, S Lemeer, B Kuster ACS chemical biology 10 (12), 2743-2752, 2015 | 42 | 2015 |
| Characterization of a chemical affinity probe targeting Akt kinases F Pachl, P Plattner, B Ruprecht, G Medard, N Sewald, B Kuster Journal of Proteome Research 12 (8), 3792-3800, 2013 | 40 | 2013 |
| Targeted diazotransfer reagents enable selective modification of proteins with azides J Lohse, LJYM Swier, RC Oudshoorn, G Médard, B Kuster, DJ Slotboom, ... Bioconjugate Chemistry 28 (4), 913-917, 2017 | 36 | 2017 |
| Salivary proteome patterns affecting human salt taste sensitivity T Stolle, F Grondinger, A Dunkel, C Meng, G Médard, B Kuster, ... Journal of agricultural and food chemistry 65 (42), 9275-9286, 2017 | 29 | 2017 |
| Effect of astringent stimuli on salivary protein interactions elucidated by complementary proteomics approaches J Delius, G Médard, B Kuster, T Hofmann Journal of agricultural and food chemistry 65 (10), 2147-2154, 2017 | 29 | 2017 |
| Dynamic proteome alteration and functional modulation of human saliva induced by dietary chemosensory stimuli M Bader, A Dunkel, M Wenning, B Kohler, G Medard, E Del Castillo, ... Journal of agricultural and food chemistry 66 (22), 5621-5634, 2018 | 27 | 2018 |
Bernhard KusterProfessor for Proteomics and BioanalyticsVerified email at tum.de
